Results 111 to 120 of about 9,703,974 (249)
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Scion and rootstock genotypes drive root system dynamics in modern apple orchards
Root systems are critical to orchard productivity and resilience, yet their size and structure remain poorly characterized in modern high-density apple (Malus × domestica) plantings.
Jean Sabety +4 more
doaj +1 more source
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
Natural roots systems exhibit various tortuous morphologies, which significantly impact the root-soil interaction characteristics. Previous studies often treated root systems as straight, neglecting the deformation characteristics and failure modes of ...
Yu DING +4 more
doaj +1 more source
Translophagy—A potential link between autophagy impairment and translational errors
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
Unit-Root, Cointegration and Granger Causality Test Results for Export and Growth in OECD Countries [PDF]
This article is a supplement to Kónya (2004) which investigates the possibility of the export-led growth and growth-driven export hypotheses by testing for Granger causality between the logarithms of real exports and real GDP in twenty-five OECD ...
Konya, Laszlo
core
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source
Women's Hospital, Madurai, India
Photograph of the woman's hospital in Madurai, India which Mary Pauline Root fought to open while on her mission in India from 1885-1893. Root graduated from the Woman's Medical College of Pennsylvania in 1883.
core
Since the seminal paper by Dickey and Fuller in 1979, unit-root tests have conditioned the standard approaches to analyse time series with strong serial dependence, the focus being placed in the detection of eventual unit roots in an autorregresive model
García, Ana +2 more
core +1 more source
Structural and biochemical analysis of a B12 superbinder
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source

