Results 141 to 150 of about 531,079 (302)

Root canal conicity of primary maxillary molars and its relationship with different rotational systems

Aim: To determine the root canal taper of primary maxillary molars and the degree of compatibility of various rsotary systems concerning root anatomy. Materials and methods: This in vitro study collected donated first and second primary molars (1 M and ...
Diéguez Pérez, Montserrat, Gallardo López, Nuria Esther, Ticona Flores, Jesús Miguel   +2 more
core   +1 more source

Transcriptome and Co-Expression Network Analysis Reveals the Molecular Mechanism of Rice Root Systems in Response to Low-Nitrogen Conditions. [PDF]

Int J Mol Sci, 2023
Wang W, Xin W, Chen N, Yang F, Li J, Qu G, Jiang X, Xu L, Zhao S, Liu H, Yang L, Zheng H, Zou D, Wang J.   +13 more
europepmc   +1 more source

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

Molecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute, Madeleine Birgersson, Paolo Ceriani, Margareta Wilhelm, Ourania N Kostopoulou   +4 more
wiley   +1 more source

Installation and imaging of thousands of minirhizotrons to phenotype root systems of field-grown plants. [PDF]

Plant Methods, 2022
Rajurkar AB, McCoy SM, Ruhter J, Mulcrone J, Freyfogle L, Leakey ADB.   +5 more
europepmc   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

A toolkit to rapidly modify root systems through single plant selection. [PDF]

Plant Methods, 2022
Rambla C, Van Der Meer S, Voss-Fels KP, Makhoul M, Obermeier C, Snowdon R, Ober ES, Watt M, Alahmad S, Hickey LT.   +9 more
europepmc   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

Molecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera, Laura Vela‐Martín, Pablo Fernández‐Navarro, José Luis López‐Lorenzo, Javier Cornago, Pilar Llamas, Eduardo Pérez‐Gómez, José Luis Marín‐Rubio, Manuel Fresno, Javier Santos, José Fernández‐Piqueras, María Villa‐Morales   +11 more
wiley   +1 more source

Autonomous fault detection in self-healing systems using Restricted Boltzmann Machines

, 2015
Funding for this research was provided by the Scottish Informatics and Computer Science Alliance (SICSA).Autonomously detecting and recovering from faults is one approach for reducing the operational complexity and costs associated with managing ...
Barker, Adam David, Schneider, Christopher, Dobson, Simon Andrew, Adam Barker, Chris Schneider, Simon Dobson   +5 more
core  

Parsimonious root systems and better root distribution can improve biomass production and yield of soybean. [PDF]

PLoS One, 2022
Noh E, Fallen B, Payero J, Narayanan S.
europepmc   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source