Results 181 to 190 of about 2,237,927 (278)

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

Molecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic, Anne Nørremølle, Lilian Bomme Ousager, Lars van Brakel Andersen, Marie Louise Mølgaard Binderup, Mads Thomassen   +5 more
wiley   +1 more source

7 Root systems and root lattices [PDF]

, 2020
  +4 more sources

Detection of plant cadmium toxicity by monitoring dielectric response of intact root systems on a fine timescale. [PDF]

Environ Sci Pollut Res Int
Cseresnyés I, Takács T, Füzy A.
europepmc   +1 more source

Phenotypic variability in bread wheat root systems at the early vegetative stage. [PDF]

BMC Plant Biol, 2020
Chen Y, Palta J, Prasad PVV, Siddique KHM.   +3 more
europepmc   +1 more source

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

Molecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute, Madeleine Birgersson, Paolo Ceriani, Margareta Wilhelm, Ourania N Kostopoulou   +4 more
wiley   +1 more source

Response of Sorghum bicolor genotypes for yield and yield components and organic carbon storage in the shoot and root systems. [PDF]

Sci Rep
Ngidi A, Shimelis H, Abady S, Figlan S, Chaplot V.   +4 more
europepmc   +1 more source

Phenotyping Root Systems in a Set of Japonica Rice Accessions: Can Structural Traits Predict the Response to Drought? [PDF]

Rice (N Y), 2020
Guimarães PHR, de Lima IP, de Castro AP, Lanna AC, Guimarães Santos Melo P, de Raïssac M.   +5 more
europepmc   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

Integrated Transcriptomic and Metabolomic Analysis of Exogenous NAA Effects on Maize Seedling Root Systems under Potassium Deficiency. [PDF]

Int J Mol Sci
Zhou D, Zhang Y, Dong Q, Wang K, Zhang H, Du Q, Wang J, Wang X, Yu H, Zhao X.   +9 more
europepmc   +1 more source

Do agricultural grasses bred for improved root systems provide resilience to machinery-derived soil compaction? [PDF]

Food Energy Secur, 2020
Muhandiram NPK, Humphreys MW, Fychan R, Davies JW, Sanderson R, Marley CL.   +5 more
europepmc   +1 more source