Results 91 to 100 of about 989,542 (371)

The solution supramolecular structure of α2 → 8 polysialic acid suggests a structural cause for its low immunogenicity

open access: yesFEBS Letters, EarlyView.
α2 → 8 polysialic acid elicits poor immunogenicity. Small‐angle scattering shows a supramolecular structure with parallel‐chain binding, although in different forms at μm and mm calcium. The major histocompatibility complex requires molecular weights around 2000 Da to produce antibodies, and 2000 Da polysialic oligomers will bind in these structures ...
Kenneth A. Rubinson
wiley   +1 more source

Complex Roots of Quaternion Polynomials [PDF]

open access: yesarXiv, 2015
The polynomials with quaternion coefficients have two kind of roots: isolated and spherical. A spherical root generates a class of roots which contains only one complex number $z$ and its conjugate $\bar{z}$, and this class can be determined by $z$. In this paper, we deal with the complex roots of quaternion polynomials.
arxiv  

The Roots of Gender Inequality in Developing Countries

open access: yes, 2014
Is the high degree of gender inequality in developing countries—in education, personal autonomy, and more—explained by underdevelopment itself? Or do the societies that are poor today hold certain cultural views that lead to gender inequality?
S. Jayachandran
semanticscholar   +1 more source

Refining the NaV1.7 pharmacophore of a class of venom‐derived peptide inhibitors via a combination of in silico screening and rational engineering

open access: yesFEBS Letters, EarlyView.
Venom peptides have shown promise in treating pain. Our study uses computer screening to identify a peptide that targets a sodium channel (NaV1.7) linked to chronic pain. We produced the peptide in the laboratory and refined its design, advancing the search for innovative pain therapies.
Gagan Sharma   +8 more
wiley   +1 more source

Trinets encode orchard phylogenetic networks [PDF]

open access: yesarXiv, 2020
Rooted triples, rooted binary phylogenetic trees on three leaves, are sufficient to encode rooted binary phylogenetic trees. That is, if $\mathcal T$ and $\mathcal T'$ are rooted binary phylogenetic $X$-trees that infers the same set of rooted triples, then $\mathcal T$ and $\mathcal T'$ are isomorphic.
arxiv  

The power of microRNA regulation—insights into immunity and metabolism

open access: yesFEBS Letters, EarlyView.
MicroRNAs are emerging as crucial regulators at the intersection of metabolism and immunity. This review examines how miRNAs coordinate glucose and lipid metabolism while simultaneously modulating T‐cell development and immune responses. Moreover, it highlights how cutting‐edge artificial intelligence applications can identify miRNA biomarkers ...
Stefania Oliveto   +2 more
wiley   +1 more source

On Generalized m-th Root Finsler Metrics [PDF]

open access: yesarXiv, 2013
In this paper, we characterize locally dually flat generalized m-th root Finsler metrics. Then we find a condition under which a generalized m-th root metric is projectively related to a m-th root metric. Finally, we prove that if a generalized m-th root metric is conformal to a m-th root metric, then both of them reduce to Riemannian metrics.
arxiv  

Geomorphodynamics, evolution, and ecology of vertical roots [PDF]

open access: yesFrontiers in Plant Science 14 (2023): 1102491
The roots of some coastal and wetland trees grow peculiar vertical protrusions, the function of which remains unclear. Here, using computational simulations based on first-principles fluid and sedimentation dynamics, we argue that the protrusions work together to create an elevated patch of sediment downstream of the tree, thereby creating its own ...
arxiv   +1 more source

The Roots of Bioinformatics

open access: yesPLoS Computational Biology, 2010
Every new scientific discipline or methodology reaches a point in its maturation where it is fruitful for it to turn its gaze inward, as well as backward. Such introspection helps to clarify the essential structure of a field of study, facilitating communication, pedagogy, standardization, and the like, while retrospection aids this process by ...
openaire   +5 more sources

Understanding deep roots and their functions in ecosystems: an advocacy for more unconventional research.

open access: yesAnnals of Botany, 2016
BACKGROUND Deep roots are a common trait among a wide range of plant species and biomes, and are pivotal to the very existence of ecosystem services such as pedogenesis, groundwater and streamflow regulation, soil carbon sequestration and moisture ...
A. Pierret   +5 more
semanticscholar   +1 more source

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