Results 131 to 140 of about 157,596 (247)

β3‐adrenoceptor agonism exerts lung protection in a rat model of bronchopulmonary dysplasia

British Journal of Pharmacology, EarlyView.
The β3‐adrenoceptors agonist BRL37344 promotes lung maturation, preventing the progression of experimental bronchopulmonary dysplasia. Absract Background and Purpose Bronchopulmonary dysplasia (BPD) affects premature newborns, particularly those receiving supplemental oxygen therapy.
Alessandro Pini, Patrizia Nardini, Virginia Zizi, Marta Molino, Maura Calvani, Francesco Carrozzo, Rachele Amato, Daniele Guasti, Denise Biagini, Fabio di Francesco, Ludovico Silvestri, Alessandra Franceschini, Daniele Bani, Elisa Imbimbo, Luca Filippi   +14 more
wiley   +1 more source

Stage‐Associated Microglial Subpopulations and Dynamics in Vascular Pathogenesis of Oxygen‐Induced Retinopathy

Cell Proliferation, EarlyView.
In the oxygen‐induced retinopathy (OIR) mouse model, two distinct microglial subpopulations play opposing roles: highly glycolytic microglia (HGM) promote neovascular formation via Pkm2, while Mrc1/CD206‐positive phagocytosis‐associated microglia (PAM) facilitate its regression.
Yuan Ma, Ziye Chen, Baoyi Liu, Wen Ding, Runping Duan, Kangjie Kong, Zhuojun Xu, Jizhu Li, Jiali Ru, Dianlei Guo, Xiaoyue Wei, Yaping Liu, Zhuangling Lin, Yang Meng, Yuan Liu, Lan Jiang, Zitong Chen, Rebiya Tuxun, Chinling Tsai, Chunqiao Liu, Tao Li   +20 more
wiley   +1 more source

Ophthalmological outcomes, visual perception, fine motor precision, and visual‐motor integration in children born very preterm

Developmental Medicine &Child Neurology, EarlyView.
Children born very preterm with poorer ophthalmological function at 2 years 6 months, 6 years 6 months, and 12 years showed poorer visuo‐perceptual, visual‐motor, and fine motor skills at 12 years, emphasizing the role of visual input in visual‐motor development.
Martin Johansson, Eva Larsson, Gerd Holmström, Olga Kochukhova, Lena Hellström‐Westas, Ylva F. Kaul   +5 more
wiley   +1 more source

Blood Immunopathology of Tuberculosis Patients Disrupts Monocyte‐Dependent T‐Cell Activation and Cytokine Expression

Immunology, EarlyView.
TB serum selectively disrupts monocyte‐dependent PHA T cell activation and cytokines associated with proliferation while preserving SEB T cell and Pam3/PHA monocyte cytokine responses. ABSTRACT Pulmonary tuberculosis in humans is characterised by features of immunopathology, which influence both antimycobacterial therapy and the long‐term prognosis. In
Joseph F. Arthur, Hubert S. Ahor, Monika M. Vivekanandan, Difery Minadzi, Augustine Yeboah, Millicent Lamptey, Victoria A. Ofori, Albert D. Kegya, Rejoice Arthur, Linda A. Amoakoa, Ernest Adankwah, Dorcas O. Owusu, Mohammed K. Abass, Fredrick Gyamfi Apraku, Nana K. Ayisi‐Boateng, Seth Adane, Salisu Zakaria, Ertan Mayatepek, Julia Seyfarth, Richard O. Phillips, Marc Jacobsen   +20 more
wiley   +1 more source

Population-Based Cohort Study for Development of National Retinopathy of Prematurity Screening Criteria. [PDF]

Acta Paediatr
ABSTRACT Aim Screening criteria for retinopathy of prematurity (ROP) vary among countries. Early detection of ROP and minimising the burden of screening are important. Methods We analysed data from very preterm infants born in Switzerland between 2006 and 2022.
Gerull R, Sanchez C, Atkinson A, Schuler-Barazzoni M, Adams M, Barcos Munoz F, Gerth-Kahlert C, Schulzke SM, Swiss Neonatal Network.   +8 more
europepmc   +2 more sources

Bridging the implementation gap in MCABC inventory management: from a taxonomy to practical archetypes

International Transactions in Operational Research, EarlyView.
Abstract Despite increasing demands for resilient and sustainable supply chains, inventory management often relies on outdated single‐criterion analyses. While multi‐criteria ABC (MCABC) analyses provide a theoretically mature assessment of resilience‐sustainability‐benefit trade‐offs in inventory, their adoption remains limited due to fragmented ...
Lukas Grützner, Michael H. Breitner
wiley   +1 more source

Hidden lineages in the African Sky Islands: A taxonomic reevaluation of Afrocarduus (Compositae)

Journal of Systematics and Evolution, EarlyView.
Species delimitation is crucial for biodiversity studies. Using Hyb‐Seq and phylogenomics, we reassessed Afrocarduus, endemic to Afromontane and Afroalpine regions, uncovering 16 evolutionary lineages (2.3 Mya). Morphological data support their distinctiveness, with acaulescence evolving independently twice. The traditionally broad A.
Lucía D. Moreyra, Juan Antonio Calleja, Cristina Roquet, Siri Birkeland, Carme Blanco‐Gavaldà, Mercè Galbany‐Casals, Abel Gizaw, Frederik Leliaert, Christian Brochmann, Alfonso Susanna   +9 more
wiley   +1 more source

Development and production of allogeneic cord blood‐derived red blood cell concentrates for transfusion to extremely preterm neonates, the All‐Cord study

Transfusion, EarlyView.
Abstract Background Extremely preterm neonates often require red blood cell (RBC) transfusions derived from adult donors. These transfusions introduce adult hemoglobin into a neonatal hematopoietic system dominated by fetal hemoglobin (HbF), shifting the oxygen‐dissociation curve and increasing oxygen delivery to immature tissues.
Jip H. van Daelen, Joyce Bestebroer, Herbert Korsten, Christie Vermeulen, Irwin K. M. Reiss, Enrico Lopriore, Pauline M. Snijder, Elise J. Huisman, Thomas R. L. Klei   +8 more
wiley   +1 more source

Association of red blood cell transfusions with periventricular leukomalacia in very preterm infants

Vox Sanguinis, EarlyView.
Abstract Background and Objectives Red blood cell (RBC) transfusions have been associated with retinopathy of prematurity (ROP) and adverse long‐term neurodevelopmental outcomes in very preterm infants. Although lower transfusion thresholds reduce the incidence of ROP, they have not improved neurological outcome. Periventricular leukomalacia (PVL) is a
Thomas Brune, Christian Weise, Siegfried Kropf   +2 more
wiley   +1 more source

ROP-ET

Interferon-based therapies, such as ropeginterferon alfa-2b have emerged as promising disease-modifying agents for myeloproliferative neoplasms (MPNs), including essential thrombocythemia (ET). Current ET treatments aim to normalize hematological parameters and reduce the thrombotic risk, but they do not modify the natural history of the disease and ...
Kiladjian, Jean-Jacques||, Ferrer Marin, Francisca, Al-Ali, Haifa Kathrin||, Álvarez Larrán, Alberto||, Beggiato, Eloise, Bieniaszewska, Maria, Breccia, Massimo||, Buxhofer-Ausch, Veronika||, Cerna, Olga, Crisan, Ana Manuela, Danaila, Catalin Doru, De Stefano, Valerio||, Döhner, Konstanze||, Empson, Victoria, Gora-Tybor, Joanna||, Griesshammer, Martin, Grosicki, Sebastian||, Guglielmelli, Paola||, García-Gutierrez, Valentín, Heidel, Florian H.||, Illés, Arpád, Tomuleasa, Ciprian, James, Chloe, Koschmieder, Steffen||, Krauth, Maria-Theresa, Krejcy, Kurt, Lazaroiu, Mihaela-Cornelia, Mayer, Jiri, Nagy, Zsolt György, Nicolini, Franck-Emmanuel, Palandri, Francesca||, Pappa, Vassiliki, Reiter, Andreas Johannes, Sacha, Tomasz||, Schlager, Stefanie, Schmidt, Stefan, Terpos, Evangelos, Unger, Martin, Wölfler, Albert, Xicoy, Blanca||, Klade, Christoph   +40 more
openaire   +1 more source