Results 1 to 10 of about 22,668 (206)

Ropivacaine inhibits wound healing by suppressing the proliferation and migration of keratinocytes via the PI3K/AKT/mTOR Pathway [PDF]

BMC Anesthesiology, 2022
Background After surgery, millions of people suffer from delayed healing or wound dehiscence with subsequent severe complications, even death. Previous studies have reported that ropivacaine exhibits anti-proliferative and anti-migratory activities on ...
Xiaoyang Wu, Quanyu Sun, Simeng He, Ya Wu, Shihan Du, Lirong Gong, Jianbo Yu, Haifeng Guo   +7 more
doaj   +2 more sources

Analgesic effect of ropivacaine with fentanyl in comparison with ropivacaine alone for continuous femoral nerve block after knee replacement arthroplasty: a prospective, randomized, double-blinded study [PDF]

Anesthesia and Pain Medicine, 2020
Background The analgesic effect of perineural opioid in clinical practice are still controversial. This randomized controlled trial compared analgesic effect of ropivacaine with fentanyl or ropivacaine alone for continuous femoral nerve block following ...
Gunn Hee Kim, Joon Woo Lee, Go Eun Kim, Seong Su Lee, Shill Lee Son, Byung Uk Kim, Ha Na Cho, Mi Young Kwon, Min Seok Koo, Ji Eun Kim, Mi Jung Yun   +10 more
doaj   +3 more sources

Ropivacaine inhibits the malignant behavior of lung cancer cells by regulating retinoblastoma-binding protein 4 [PDF]

PeerJ, 2023
Background Ropivacaine is a local anesthetic commonly used in regional nerve blocks to manage perioperative pain during lung cancer surgery. Recently, the antitumor potential of ropivacaine has received considerable attention.
Weiai Jia, Junmei Shen, Sisi Wei, Chao Li, Jingpu Shi, Lianmei Zhao, Huiqun Jia   +6 more
doaj   +2 more sources

Subfascial infiltration of 0.5% ropivacaine, but not 0.25% ropivacaine, exacerbates damage and inflammation in surgically incised abdominal muscles of rats

Scientific Reports, 2022
Ropivacaine-induced myotoxicity in surgically incised muscles has not been fully investigated. We evaluated the effects of infiltration anesthesia with ropivacaine on damage, inflammation and regeneration in the incised muscles of rats undergoing ...
Dandan Shen, Yuki Sugiyama, Kumiko Ishida, Satoshi Fuseya, Takashi Ishida, Mikito Kawamata, Satoshi Tanaka   +6 more
doaj   +1 more source

Ropivacaine as the drug of choice for regional anesthesia: why so?

Медицина болю, 2021
While writing the article, we analyzed all the studies related to ropivacaine for the first half of 2021, which were published in PubMed. Previous review articles on ropivacaine were also analyzed.
Dmytro Dmytriiev, Yevhen Lisak
doaj   +1 more source

Methylprednisolone as an Adjunct to Local Infiltration on Laminoplasty or Laminectomy before Wound Closure: A Randomized Controlled Trial

Pain Research and Management, 2022
TrialDesign. Patients undergoing laminoplasty and laminectomy often experience severe postoperative pain. Local infiltration analgesia during spine surgery significantly reduces postoperative pain, which only upholds for a short time.
Niti Shrestha, Bo Han, Xiying Wang, Wenqing Jia, Fang Luo   +4 more
doaj   +1 more source

Comparison of anaesthetic efficacy of ropivacaine (0.75% & 0.5%) with 2% lignocaine with adrenaline (1:200000) in surgical extraction of bilateral mandibular 3rd molars using IANB:a prospective, randomized, single blind study

Journal of Oral Biology and Craniofacial Research, 2021
Aim: To evaluate and compare the anaesthetic efficacy of 0.75% ropivacaine and 0.5% ropivacaine with 2% lignocaine with 1:200000 Adrenaline (LWA) for surgical extraction of bilateral mandibular 3rd molars using Direct inferior alveolar nerve block (IANB).
Kamil N. Rajpari, Neelam N. Andrade, Trupti Nikalje   +2 more
doaj   +1 more source

Encapsulation of ropivacaine in a combined (donor-acceptor, ionic-gradient) liposomal system promotes extended anesthesia time. [PDF]

PLoS ONE, 2017
Ropivacaine is a local anesthetic with similar potency but lower systemic toxicity than bupivacaine, the most commonly used spinal anesthetic. The present study concerns the development of a combined drug delivery system for ropivacaine, comprised of two
Camila Morais Gonçalves da Silva, Michelle Franz-Montan, Cíntia Elisabeth Gomez Limia, Lígia Nunes de Morais Ribeiro, Mário Antônio Braga, Viviane Aparecida Guilherme, Camila Batista da Silva, Bruna Renata Casadei, Cíntia Maria Saia Cereda, Eneida de Paula   +9 more
doaj   +1 more source

The role of DRP1 in ropivacaine-induced mitochondrial dysfunction and neurotoxicity

Artificial Cells, Nanomedicine, and Biotechnology, 2019
Ropivacaine is a commonly used local anaesthetic, but its side effects remain largely unknown. In the present study, we investigated the side effects of ropivacaine in human neuronal SH-5Y5Y cells. We show that 0.5% and 1% ropivacaine could cause fission-
Yan Chen, Lili Yan, Yan Zhang, Xianhui Yang   +3 more
doaj   +1 more source

Effect of ropivacaine combined with pancuronium on neuromuscular transmission and effectiveness of neostigmine and 4-aminopyridine for blockade reversal: experimental study

Revista Brasileira de Anestesiologia, 2015
BACKGROUND AND OBJECTIVES: The local anesthetic effects on neuromuscular junction and its influence on blockade produced by nondepolarizing neuromuscular blockers are still under-investigated; however, this interaction has been described in experimental ...
Angélica de Fátima Braga, Vanessa Henriques Carvalho, Franklin Sarmento Braga, Gloria Maria Braga Potério, Filipe Nadir Caparica Santos   +4 more
doaj   +1 more source