Results 1 to 10 of about 34,796 (225)

Impact of temperature on EC₅₀ of ropivacaine in axillary brachial plexus blocks: based on Dixon's up-and-down method. [PDF]

Front Med (Lausanne)
ObjectiveThe efficacy of local anesthetics like ropivacaine in axillary brachial plexus blocks may be influenced by temperature, though its impact on the median effective concentration (EC50) remains unclear.
Wang A, Shao Y, Zheng Y, Li X, Huang B, Mai Y, Zhang Z.   +6 more
europepmc   +2 more sources

Ropivacaine as a novel AKT1 specific inhibitor regulates the stemness of breast cancer [PDF]

Journal of Experimental & Clinical Cancer Research
Background Ropivacaine, a local anesthetic, exhibits anti-tumor effects in various cancer types. However, its specific functions and the molecular mechanisms involved in breast cancer cell stemness remain elusive.
Lin Ding, Hui Jiang, Qiangwei Li, Qiushuang Li, Tian-Tian Zhang, Limeng Shang, Bin Xie, Yaling Zhu, Keshuo Ding, Xuanming Shi, Tao Zhu, Yong Zhu   +11 more
doaj   +2 more sources

Comparative Study of Ropivacaine Alone Versus Combination of Ropivacaine with Either Dexmedetomidine or Dexamethasone for Ultrasound Guided Supraclavicular Brachial Plexus Block

Journal of Karnali Academy of Health Sciences
Background: Ropivacaine is a common choice for supraclavicular brachial plexus block. Dexmedetomidine and Dexamethasone are frequently added to local anesthetics for improved effects.
Kumud Pyakurel, Kanak Khanal, Sonia Dahal   +2 more
doaj   +5 more sources

Labor Analgesia Initiation with Dural Puncture Epidural versus Standard Epidural Techniques: A Prospective Randomized Dose Allocation Study of Ropivacaine. [PDF]

Drug Des Devel Ther
Xiao F, Drzymalski DM, Dong YF, Huang JY, Gao Y, Yan HY, Hu HJ.   +6 more
europepmc   +3 more sources

Local anesthetic ropivacaine inhibits non-small cell lung cancer progression by modulating the hsa_circ_0001320/miR-518a-5p axis. [PDF]

Hereditas
Objective This study investigated the possible mechanisms by which ropivacaine influences the progression of non-small cell lung cancer (NSCLC). Methods Plasmid vectors or oligonucleotides interfering with circ_0001320 or miR-518a-5p were transfected ...
Cheng L, Shen R, Ma Z, Guo Y, Peng Y.
europepmc   +2 more sources

Ropivacaine inhibits the malignant behavior of lung cancer cells by regulating retinoblastoma-binding protein 4 [PDF]

PeerJ, 2023
Background Ropivacaine is a local anesthetic commonly used in regional nerve blocks to manage perioperative pain during lung cancer surgery. Recently, the antitumor potential of ropivacaine has received considerable attention.
Weiai Jia, Junmei Shen, Sisi Wei, Chao Li, Jingpu Shi, Lianmei Zhao, Huiqun Jia   +6 more
doaj   +2 more sources

Subfascial infiltration of 0.5% ropivacaine, but not 0.25% ropivacaine, exacerbates damage and inflammation in surgically incised abdominal muscles of rats

Scientific Reports, 2022
Ropivacaine-induced myotoxicity in surgically incised muscles has not been fully investigated. We evaluated the effects of infiltration anesthesia with ropivacaine on damage, inflammation and regeneration in the incised muscles of rats undergoing ...
Dandan Shen, Yuki Sugiyama, Kumiko Ishida, Satoshi Fuseya, Takashi Ishida, Mikito Kawamata, Satoshi Tanaka   +6 more
doaj   +1 more source

Ropivacaine as the drug of choice for regional anesthesia: why so?

Медицина болю, 2021
While writing the article, we analyzed all the studies related to ropivacaine for the first half of 2021, which were published in PubMed. Previous review articles on ropivacaine were also analyzed.
Dmytro Dmytriiev, Yevhen Lisak
doaj   +1 more source

Methylprednisolone as an Adjunct to Local Infiltration on Laminoplasty or Laminectomy before Wound Closure: A Randomized Controlled Trial

Pain Research and Management, 2022
TrialDesign. Patients undergoing laminoplasty and laminectomy often experience severe postoperative pain. Local infiltration analgesia during spine surgery significantly reduces postoperative pain, which only upholds for a short time.
Niti Shrestha, Bo Han, Xiying Wang, Wenqing Jia, Fang Luo   +4 more
doaj   +1 more source

Comparison of anaesthetic efficacy of ropivacaine (0.75% & 0.5%) with 2% lignocaine with adrenaline (1:200000) in surgical extraction of bilateral mandibular 3rd molars using IANB:a prospective, randomized, single blind study

Journal of Oral Biology and Craniofacial Research, 2021
Aim: To evaluate and compare the anaesthetic efficacy of 0.75% ropivacaine and 0.5% ropivacaine with 2% lignocaine with 1:200000 Adrenaline (LWA) for surgical extraction of bilateral mandibular 3rd molars using Direct inferior alveolar nerve block (IANB).
Kamil N. Rajpari, Neelam N. Andrade, Trupti Nikalje   +2 more
doaj   +1 more source