Results 21 to 30 of about 15,258 (169)

Anesthetic efficacy and safety of ropivacaine 0.75% versus bupivacaine 0.5% for spinal anesthesia in patients undergoing lower limb orthopedic surgery

Asian Journal of Medical Sciences, 2023
Background: Ropivacaine, a new amino-amide local anesthetic agent, is similar in chemical structure to bupivacaine. The low solubility of ropivacaine leads to greater sensory-motor differentiation by blocking sensory nerve fiber more readily than motor ...
Pratiti J Gohil , Pankti Panchal , Gauri M. Panjabi , Jinal J. Gohil , Ushma H. Thakar , Raghav R. Rathi   +5 more
doaj   +1 more source

Comparative study of intrathecal hyperbaric versus isobaric ropivacaine: A randomized control trial

Saudi Journal of Anaesthesia, 2013
Background: Hyperbaric ropivacaine produce more reliable sensory and motor block, with faster onset, better quality of muscles relaxation than isobaric ropivacaine.
Rajni Gupta, Jaishri Bogra, Prithvi Kumar Singh, Sulekha Saxena, Girish Chandra, Jitendra Kumar Kushwaha   +5 more
doaj   +1 more source

Comparison of clinical efficacy of intrathecal ropivacaine versus ropivacaine with dexmedetomidine in patient posted for infraumbilical surgeries under spinal anesthesia

Asian Journal of Medical Sciences, 2022
Background: Data related to clinical efficacy of intrathecal dexmedetomidine as an adjuvant to isobaric ropivacaine in spinal anesthesia were found to be inadequate, but the efficacy of newer molecules as an adjuvant is investigated constantly ...
Isha Yadav , Ankita Aggarwal, Mahima lakhanpal , Himanshu Nirvan   +3 more
doaj   +1 more source

Ropivacaine withdrawal syndrome: a case report [PDF]

Revista Brasileira de Anestesiologia, 2020
Introduction and objectives: Ropivacaine is a long-acting local anesthetic that causes prolonged anesthesia and is beneficial for a wide variety of surgeries.
Dmitriy Viderman, Ivan Portnyagin, Philip la Fleur, Federico Bilotta   +3 more
doaj   +3 more sources

Impact of temperature on EC50 of ropivacaine in axillary brachial plexus blocks: based on Dixon’s up-and-down method

Frontiers in Medicine
ObjectiveThe efficacy of local anesthetics like ropivacaine in axillary brachial plexus blocks may be influenced by temperature, though its impact on the median effective concentration (EC50) remains unclear.
Alin Wang, Yunhao Shao, Yuling Zheng, Xiaoling Li, Bixin Huang, Ying Mai, Zhongqi Zhang   +6 more
doaj   +1 more source

Serum Concentration of Ropivacaine After Repeated Administration to Several Parts of the Head During Awake Craniotomy: A Prospective Cohort Study

Frontiers in Medicine, 2022
IntroductionDuring awake craniotomy, effective use of local anesthetics, such as ropivacaine, is critical. Blood concentrations of ropivacaine after repeated administration over a short period during awake craniotomy have not been studied.Materials and ...
Takehito Sato, Takahiro Ando, Ichiko Asano, Atsushi Mori, Kazuya Motomura, Kimitoshi Nishiwaki   +5 more
doaj   +1 more source

Comparison of caudal analgesia between ropivacaine and ropivacaine with clonidine in children: A randomized controlled trial

Saudi Journal of Anaesthesia, 2012
Background: Addition of clonidine to ropivacaine (0.2%) can potentially enhance analgesia without producing prolonged motor blockade. The aim of the present study was to compare the post-operative pain relieving quality of ropivacaine 0.2% and clonidine ...
Arpita Laha, Sarmila Ghosh, Haripada Das
doaj   +1 more source

The Median Effective Analgesic Concentration of Ropivacaine in Sciatic Nerve Block Guided by Ultrasound After Arthroscopic Anterior Cruciate Ligament Reconstruction: A Double-Blind Up-Down Concentration-Finding Study

Frontiers in Medicine, 2022
BackgroundThe median effective analgesic concentration (MEAC; EC50 = effective concentration in 50% patients) of ropivacaine in sciatic nerve block guided by ultrasound (US) required for effective postoperative analgesia following arthroscopic anterior ...
Cheng Xu, Fei Gu, Chengyu Wang, Yang Liu, Rui Chen, Quanhong Zhou, Jie Lu   +6 more
doaj   +1 more source

Controlled Release of Ropivacaine from Single-Armed (1-PCL) and Four-Armed PCL (4-PCL) Microspheres

International Journal of Polymer Science, 2019
Sustained release of anesthesia has shown great promise in the treatment of chronic pain in patients. In this research, we used neutralized ropivacaine as an anesthesia and poly(ε-caprolactone) (PCL) with different architectures to systematically study ...
Wei Xiong, Yue-kun Shen, Peng Dong, Ying Xiao, Xiong-qing Huang, Wen-qi Huang, Lu Yang, Xia Feng   +7 more
doaj   +1 more source

Quantitative prediction of intravenous drug interactions caused by cytochromes P450 inhibitors and inducers

British Journal of Clinical Pharmacology, EarlyView.
Background Aims Pharmacokinetic interaction studies typically focus on oral administration, but intravenous (IV) administration bypasses intestinal degradation and hepatic first‐pass metabolism, leading to distinct drug–drug interaction (DDI) magnitude. This study aimed to develop a predictive model for DDIs involving IV‐administered drugs.
Vianney Tuloup, Michel Tod, Laurent Bourguignon   +2 more
wiley   +1 more source