Results 21 to 30 of about 15,372 (163)

Controlled Release of Ropivacaine from Single-Armed (1-PCL) and Four-Armed PCL (4-PCL) Microspheres

International Journal of Polymer Science, 2019
Sustained release of anesthesia has shown great promise in the treatment of chronic pain in patients. In this research, we used neutralized ropivacaine as an anesthesia and poly(ε-caprolactone) (PCL) with different architectures to systematically study ...
Wei Xiong, Yue-kun Shen, Peng Dong, Ying Xiao, Xiong-qing Huang, Wen-qi Huang, Lu Yang, Xia Feng   +7 more
doaj   +1 more source

Ropivacaine alleviates LPS-induced apoptosis of ulcerative colitis cell line NCM-460 [PDF]

Jichu yixue yu linchuang
Objective To investigate the impact of ropivacaine on apoptosis of lippolysaccharide(LPS) -induced ulcerative colitis cell line NCM-460 and on activity of nucleotide oligomerization domain (NOD)-like receptor protein-3 (NLRP3) inflammatome.Methods ...

doaj   +1 more source

Effect of ropivacaine combined with sufentanil epidural anesthesia in abdominal surgery

Pakistan Journal of Pharmaceutical Sciences, 2023
To explore and analyze the effect of ropivacaine plus sufentanil for epidural anesthesia during abdominal surgery, a total of 120 patients who underwent abdominal surgery at our institution between May 2019 and November 2020 were recruited and randomly ...
Songfeng Li, Yong Zhan, Shaojin Bu, Yalin Tian, Chunyan Xiong, Jintao Shen, Ke Liu   +6 more
doaj   +1 more source

The Median Effective Analgesic Concentration of Ropivacaine in Sciatic Nerve Block Guided by Ultrasound After Arthroscopic Anterior Cruciate Ligament Reconstruction: A Double-Blind Up-Down Concentration-Finding Study

Frontiers in Medicine, 2022
BackgroundThe median effective analgesic concentration (MEAC; EC50 = effective concentration in 50% patients) of ropivacaine in sciatic nerve block guided by ultrasound (US) required for effective postoperative analgesia following arthroscopic anterior ...
Cheng Xu, Fei Gu, Chengyu Wang, Yang Liu, Rui Chen, Quanhong Zhou, Jie Lu   +6 more
doaj   +1 more source

Comparison of clinical efficacy of intrathecal ropivacaine versus ropivacaine with dexmedetomidine in patient posted for infraumbilical surgeries under spinal anesthesia

Asian Journal of Medical Sciences, 2022
Background: Data related to clinical efficacy of intrathecal dexmedetomidine as an adjuvant to isobaric ropivacaine in spinal anesthesia were found to be inadequate, but the efficacy of newer molecules as an adjuvant is investigated constantly ...
Isha Yadav , Ankita Aggarwal, Mahima lakhanpal , Himanshu Nirvan   +3 more
doaj   +1 more source

Impact of temperature on EC50 of ropivacaine in axillary brachial plexus blocks: based on Dixon’s up-and-down method

Frontiers in Medicine
ObjectiveThe efficacy of local anesthetics like ropivacaine in axillary brachial plexus blocks may be influenced by temperature, though its impact on the median effective concentration (EC50) remains unclear.
Alin Wang, Yunhao Shao, Yuling Zheng, Xiaoling Li, Bixin Huang, Ying Mai, Zhongqi Zhang   +6 more
doaj   +1 more source

Ropivacaine promotes apoptosis of hepatocellular carcinoma cells through damaging mitochondria and activating caspase-3 activity

Biological Research, 2019
Background Recent evidences indicated that some local anaesthetic agents played a role in inhibiting the proliferation of cancer cells; Whether ropivacaine is able to promote apoptosis of hepatocellular carcinoma (HCC) cells is still unclear.
Wenting Wang, Mingyue Zhu, Zhixin Xu, Wei Li, Xu Dong, Yi Chen, Bo Lin, Mengsen Li   +7 more
doaj   +1 more source

Nail Surgery in Children: Specific Challenges and Practical Considerations

JEADV Clinical Practice, EarlyView.
ABSTRACT Nail surgery in children represents a specific field within dermatologic surgery. Although the procedures themselves are largely similar to those performed in adults, the indications, technical constraints, and perioperative management differ substantially. Pediatric nail disorders are often clinically recognizable, which frequently limits the
F. Lamoline, B. Richert
wiley   +1 more source

Ultrasound‐Guided Thoracic Paravertebral Block With Liposomal Versus Standard Bupivacaine for Older Patients After Thoracoscopic Surgery

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT The study aimed to investigate the effect of thoracic paravertebral block (TPVB) with liposomal bupivacaine (LB) before anesthesia induction on postoperative pain, quality of recovery (QoR), and opioid consumption in older patients after video‐assisted thoracoscopic surgery (VATS).
Wen‐Cheng Shi, Ying‐Jie Tang, Yao Wang, Zhong Zheng, Jing He   +4 more
wiley   +1 more source

Serum Concentration of Ropivacaine After Repeated Administration to Several Parts of the Head During Awake Craniotomy: A Prospective Cohort Study

Frontiers in Medicine, 2022
IntroductionDuring awake craniotomy, effective use of local anesthetics, such as ropivacaine, is critical. Blood concentrations of ropivacaine after repeated administration over a short period during awake craniotomy have not been studied.Materials and ...
Takehito Sato, Takahiro Ando, Ichiko Asano, Atsushi Mori, Kazuya Motomura, Kimitoshi Nishiwaki   +5 more
doaj   +1 more source