Results 191 to 200 of about 1,125,981 (241)

A CD14‐Targeting In Situ Hydrogel Directs Macrophage Reprogramming to Minimize Scar Formation

Advanced Science, EarlyView.
A CD14‐targeting in situ hydrogel formed from a microbial polysaccharide rapidly remodels the immune microenvironment by reprogramming macrophage polarization, suppressing excessive inflammation, and coordinating tissue regeneration. This multifunctional hydrogel promotes scar‐reduced wound repair through enhanced angiogenesis, collagen remodeling, and
Rui Fang, Simeng Chen, Qiaozhen Liu, Wenwen Ni, Xi Xu, Jianfa Zhang   +5 more
wiley   +1 more source

Membrane-camouflaged metal-phenolic nanomedicines for the treatment of ischemic stroke via relieving oxidative stress and neuroinflammation. [PDF]

Mater Today Bio
Liu B, Chen X, Tu L, Yin L, Huang H, Wu Y, Cai H, Li Y, Hong S.   +8 more
europepmc   +1 more source

Supramolecular Zinc–Polyphenol Coordination Assemblies Mitigate Colonic Inflammation by Regulating Mucosal Barrier and Microbiome

Advanced Science, EarlyView.
A carrier‐free zinc‐coordinated polyphenol nanoplatform (ZnCA NPs) is designed as an “all‐in‐one” therapeutic strategy for intestinal inflammation. The ZnCA NPs exhibit enhanced colonic accumulation and broad‐spectrum reactive oxygen and nitrogen species scavenging.
Qiwen Xie, Mai Ye, Xuexia Liu, Jing Wang, Ying Chen, Lu Tan, Jinheng Fu, Xiaochang Huang   +7 more
wiley   +1 more source

Biomedical Hydrogel Bio-Adhesive Based on Lactobionic Acid Conjugated Polyethylenimine and Oxidized Dextran with Antioxidant Activity and Cytocompatibility. [PDF]

Pharmaceutics
Nie L, Hu X, Cheng S, Liang Y, Wang L, Guo W.   +5 more
europepmc   +1 more source

Sequential Regulation of Neurovascular Bone Regeneration in Large Bone Defects Using Black Phosphorus‐Europium Nanosheet Integrated TPMS Biomimetic Scaffold with Photo‐Controlled Ion Release

Advanced Science, EarlyView.
TPBE scaffolds, in conjunction with mild photothermal effects, effectively activate the PI3K/Akt signaling cascade, thereby promoting early neuronal differentiation and neurite growth. Short‐term (12 W) in vivo implantation studies revealed no significant pathological damage to major organs, providing preliminary evidence of the material's excellent ...
Bingqian Wang, Yuping Zhang, Xiaoning Su, Ning Liu, Hui Zeng, Bo Yang, Yang Xue, Fang Guo, Changkui Liu   +8 more
wiley   +1 more source

Bioinspired BG/PPDO-CNP/Pluronic F-127 hydrogel fibrous dura mater with temporally programmed degradation and adhesion prevention inspired by the hierarchical architecture of dragonfly wings. [PDF]

Regen Biomater
Mao J, Zheng H, Zeng Q, Zhang W, Liu Q, Shen T, Zhang X, Tang Y, Tang W, Lv G.   +9 more
europepmc   +1 more source

Multifunctional Zinc Glycyrrhizinate‐Integrated Gel for Enhanced Probiotic Delivery and Alleviation of Acute and Spontaneous Colitis

Advanced Science, EarlyView.
Multifunctional oral delivery system—L. reuteri@ZGM—act as both a carrier and therapeutic adjuvant, providing ROS scavenging, and mucin‐interactive properties tailored to the IBD microenvironment. This bioactive gel safeguards L. reuteri from gastric degradation, enhances mucosal adhesion, and promotes long‐term retention at inflamed sites, thereby ...
Mengyun Peng, Xiaochun Chen, Wei Li, Shu Tang, Jun Zhou, Xia Wu, Dan Yuan, Zhongyan Shan, Junfeng Shi   +8 more
wiley   +1 more source

Photo-responsive nanozymes: from photocatalytic mechanisms to precision therapy. [PDF]

Front Chem
Linghu T, Gu X, Chang G, Sun X, Zhang R.
europepmc   +1 more source

A dual-pronged strategy: multi-bioactive nanoplatform synergizes ROS antidote and iron stabilization to protect against liver ischemia-reperfusion injury. [PDF]

J Nanobiotechnology
Dong J, Zhu P, Gao C, Wang Q, Zhang J, Han Y, Feng R, Chen T, Sun J, Zhang R.   +9 more
europepmc   +1 more source