Results 71 to 80 of about 1,125,981 (241)

Polynucleotide HPTTM-Based Hydrogels Exhibit Scavenging Activity Against Reactive Oxygen Species

This study investigates the scavenger activity of Polynucleotide High Purification Technology (PN HPTTM), alone or in combination with hyaluronic acid (PN HPTTM + HA) against oxidative stress induced by hydrogen peroxide (H2O2). Since oxidative stress is
Maria Teresa Colangelo, Stefano Guizzardi, Silvana Belletti, Carlo Galli   +3 more
core   +1 more source

Crosstalks of GB biosynthesis, ROS-scavenging system and proline accumulation under stressful conditions.

, 2012
The overexpression of SoBADH directly causes a higher accumulation of GB, in addition to the native GB production, and alters redox homeostasis, leading to more NAD(P)H production, which facilitates proline accumulation and ROS scavenging.
Hongxia Zhang (164388), Peng Zhang (2071), Weijuan Fan (164383), Min Zhang (111999)   +3 more
core   +1 more source

Searching speeds and the energetic feasibility of an obligate whale-scavenging fish [PDF]

, 2005
Two recently published models reach opposite conclusions on the energetic feasibility of a scavenging fish that specialises oil whale carcasses. We argue that the key difference between these models lies in their estimate of the likely searching speed of
Ruxton, Graeme D., Bailey, David M
core   +1 more source

Engineering Approaches to Modify Immunomodulatory Functions of Mesenchymal Stromal Cells (MSCs): Tissue Regeneration and Clinical Application

Advanced Science, EarlyView.
Mesenchymal stromal cells (MSCs) show promise for treating immune‐related disorders through immunomodulation and tissue regeneration. This review gives a brief overview of current clinical approval of MSC therapies. It also discussed how bioengineering, including genetic modification, biomaterial delivery, extracellular vesicles, and iPSC‐derived MSCs,
Sichen Yang, Kejia Li, Ning Wang, Zhen Li, Zhiyong Zhang, Rocky S. Tuan, Yangzi Jiang   +6 more
wiley   +1 more source

ROS-Industrial in Europe

, 2014
18 FolienThe ROS-Industrial consortium was founded to accelerate the adoption of ROS for industrial applications. This talk focuses on the ROS-Industrial Consortium in Europe and highlights the consortium structure and membership levels as well as the ...
Weisshardt, Florian
core   +1 more source

ROS Self‐Supply Nanoplatform Based on Fenton Catalyst for Chemodynamic and Immunotherapy: Reprogramming Cold Tumor Into Hot Tumor in Cancer Treatment

Advanced Science, EarlyView.
A multifunctional HA‐conjugated nanoplatform (HA‐PGMC) integrates CuO2, glucose oxidase, and mil‐100 to enable cascade catalytic ROS generation in tumor microenvironments. This self‐supplying ROS strategy induces immunogenic cell death, reprograms “cold” tumors into “hot” ones, and synergizes with PD‐L1 blockade, achieving potent chemodynamic ...
Man Lung Lee, Jack Chun Hin Chen, Wai Wing Cheng, Kwan Yee Lau, Hiu Yee Kwan, Ngar‐Yun Ellen Poon, Hung‐Wing Li   +6 more
wiley   +1 more source

NIR‐II‐Trackable LYTACs Phyto‐Nanotheranostics for Source‐Microenvironment Dual‐Track ROS Regulation in Acute Gouty Arthritis

Advanced Science
The acute gouty arthritis (GA) is critically driven by the NOX2‐mediated reactive oxygen species (ROS) explosion in macrophages, while current clinical drugs lack precise regulatory capability.
Jian Zhang, Yingying Wang, Lujie Yu, Chunmei Jiang, Haoyu Liu, Yaohua Chen, Shutong Wu, Qin Liu, Lingling Wei, Xiaochun Zheng, Huifang Hao, Mengting Gao, Weiwei Kang, Rong Dai, Ziliang Zheng, Ruiping Zhang   +15 more
doaj   +1 more source

Selenium Nanoparticles Selectively Target KRAS G13D to Inhibit Colorectal Cancer

Advanced Science, EarlyView.
The mechanisms of SeNPs therapy in cancer treatment, encompass three parallel actions: (1) seleno‐amino acids, key metabolites, upregulate GPX2 expression, thereby inhibiting tumor metastasis via the GPX2‐HIF1α‐VEGF signaling pathway; (2) selenite (SeO32−), an inorganic metabolite, forms hydrogen bonds with amino acid residues 13–17 of the KRAS G13D ...
Xiaoting Liu, Chong Wu, Shiyao Song, Li Ma, Shaoqing Huang, Yuting He, Qinghai Li, Yanzhou Chang, Dan Jiang, Yong Mei, Junchao Cai, Zhenshuang Du, Tianfeng Chen, Weiling He   +13 more
wiley   +1 more source

ROS-Targeted Depression Therapy via BSA-Incubated Ceria Nanoclusters

, 2022
Depression is one of the most fatal mental diseases, and there is currently a lack of efficient drugs for the treatment of depression. Emerging evidence has indicated oxidative stress as a key pathological feature of depression.
Xiaohuan Xia (2579809), Xiangyu Li (1475548), Bingbo Zhang (1543171), Yi Wang (32470), Weitao Yang (838638), Jialin C. Zheng (6893591), Huili Chen (1887574), Shu Zhao (435198), Qingyuan Cai (12562345), Xiaonan Xu (844921), Shengyang Fu (12562342), Pu Ai (9628305), Jie Zhu (126574)   +12 more
core   +1 more source

Ultrasound‐Activatable Piezoelectric Hydrogel Reprograms Mitochondrial Epigenetics for Osteoarthritis Therapy via the mTOR/GATD3A Axis

Advanced Science, EarlyView.
An ultrasound‐activatable piezoelectric hydrogel reprograms chondrocyte mitochondrial epigenetics via the mTOR/GATD3A axis, clearing damaged mitochondria and alleviating osteoarthritis progression in both mouse models and human cartilage explants. ABSTRACT The avascular nature of cartilage hinders drug delivery for osteoarthritis (OA) therapy.
Hui Zheng, Pengfei Yan, Peng Liu, Chang Yan, Mengqi Zhao, Zuyong Wang, Chao Ma, Rongkai Zhang, Xi Cui, Swee Hin Teoh   +9 more
wiley   +1 more source