Results 101 to 110 of about 859,090 (292)
Frontiers in Bioscience-LandmarkBackground: The mechanisms underlying the effects of pharmacological mitochondrial ATP-sensitive K+ channel (mKATP) channel openers on the functional effects of the mKATP channels opening remain disputable.
Olga V. Akopova, Anton Smirnov
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Jolkinolide B induces reactive oxygen species accumulation and endoplasmic reticulum stress and inhibits MAPK and AKT signaling activation in renal cancer cells [PDF]
Journal of Men's HealthTo investigate the impact of Jolkinolide B (JB) on renal cell carcinoma (RCC), we treated RCC cell lines with various concentrations of JB (0, 5, 25, 50 and 100 μM) for 24 hours and assessed cell viability using the cell counting kit-8 (CCK-8 ...
Xuan Wu +6 more
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Recent insights into the molecular mechanism of ubiquinol oxidation by cytochrome bc1
FEBS Open Bio, EarlyView.The review reflects on the mechanism of the catalytic reaction in cytochrome bc1: the electron bifurcation that involves the separation of two electrons derived from the quinol oxidation to opposite sides of the enzyme across the membrane. This review summarizes the long‐standing effort to understand the mechanism of quinol oxidation catalyzed by ...
Anna Wójcik‐Augustyn +2 more
wiley +1 more source
Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level
Aging and Cancer, EarlyView.This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
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Social Media and Its Impact on Children’s Behavioral Development
International Journal of Child Development and Mental HealthSocial media has become an integral part of children’s lives, influencing how they communicate, learn, and perceive the world. This paper explores the impact of social media on children’s behavioral development, highlighting both positive and negative ...
Siraluck Puttapratimonk
doaj
Aging and Cancer, EarlyView.Cancer treatment is associated with measurable acceleration of biological aging across epigenetic, telomere, senescence, and immune biomarkers. However, biomarker validation and interventional strategies remain limited, especially in hematologic malignancies, underscoring the need for standardized multi‐omic aging assessments and adequately powered ...
Moataz Ellithi +3 more
wiley +1 more source
Adolescent Mental Health: Importance and Contributing Factors
International Journal of Child Development and Mental HealthAdolescent mental health plays a crucial role in their overall development, affecting emotional stability, academic performance, and social adaptation.
Siraluck Puttapratimonk
doaj
Toward learning the rules that predict siRNA efficacy
Molecular Therapy: Nucleic Acids, 2023 Xavier Bofill-De Ros
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Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To assess the association and discriminative performance of serum biomarkers with clinical disease progression and survival in patients with amyotrophic lateral sclerosis (ALS). Methods This retrospective study, conducted at Houston Methodist Hospital, Houston, TX, used longitudinal serum samples collected between January 2018 and ...
David R. Beers +7 more
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ROS - in der industriellen Anwendung
, 2022 In der Forschung und Vorentwicklung ist das Open Source »Robot Operating System« (ROS) bereits etabliert. Aber ROS beinhaltet auch viele hochentwickelte Softwarekomponenten, die für industrielle Anwendungen vielversprechende Einsatzmöglichkeiten bieten ...
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