Results 101 to 110 of about 1,619,067 (258)
Glucose deprivation activates a metabolic and signaling amplification loop leading to cell death. [PDF]
, 2012 The altered metabolism of cancer can render cells dependent on the availability of metabolic substrates for viability. Investigating the signaling mechanisms underlying cell death in cells dependent upon glucose for survival, we demonstrate that glucose ...
Graeber, Thomas G +12 more
core
Social Media and Its Impact on Children’s Behavioral Development
International Journal of Child Development and Mental HealthSocial media has become an integral part of children’s lives, influencing how they communicate, learn, and perceive the world. This paper explores the impact of social media on children’s behavioral development, highlighting both positive and negative ...
Siraluck Puttapratimonk
doaj
PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines
FEBS Open Bio, EarlyView.Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart +7 more
wiley +1 more source
Hypobranching Induced by Both Environmental Antioxidants and ROS Metabolism Gene Knockouts in Neurospora Crassa [PDF]
, 2015 Previous work suggested a role of reactive oxygen species (ROS) metabolism on branch density, the statistical distribution of physical distances between branch points along a growing hypha in Neurospora. Here we report the results of experiments designed
Abduljabar, Hamzah +3 more
core +2 more sources
Adolescent Mental Health: Importance and Contributing Factors
International Journal of Child Development and Mental HealthAdolescent mental health plays a crucial role in their overall development, affecting emotional stability, academic performance, and social adaptation.
Siraluck Puttapratimonk
doaj
ارتباط واریانت ژنتیکی rs4252499 در ژن TRPV5با بیماری سنگ کلیه [PDF]
Majallah-i Dānishkadah-i Pizishkī-i Dānishgāh-i ̒ Ulūm-i Pizishkī-i Mashhad.مقدمه: بیماری سنگ کلیه نوعی اختلال بالینی است که نشان میدهد، کاهش یون کلسیم و افزایش ROS منجر به آسیب بافت کلیه میشود. پروتئینTRPV5 به عنوان تنظیم کننده ROS در سلول عمل میکند.
زهره مدرس +1 more
doaj +1 more source
FEBS Open Bio, EarlyView.14‐day casting‐induced immobilization reduced gastrocnemius muscle mass and increased non‐heme iron and ferritin heavy chain levels. Despite iron accumulation, transferrin receptor 1 and iron regulatory protein 2 were paradoxically upregulated. Lipid peroxidation was elevated without compensatory antioxidant responses.
Haruka Yokogawa +2 more
wiley +1 more source
Integrins engage mitochondrial function for signal transduction by a mechanism dependent on Rho GTPases. [PDF]
, 2002 We show here the transient activation of the small GTPase Rac, followed by a rise in reactive oxygen species (ROS), as necessary early steps in a signal transduction cascade that lead to NFkappaB activation and collagenase-1 (CL-1)/matrix ...
Werb, Zena, Werner, Erica
core
Baire reductions and good Borel reducibilities
, 2010 In reference [8] we have considered a wide class of "well-behaved" reducibilities for sets of reals. In this paper we continue with the study of Borel reducibilities by proving a dichotomy theorem for the degree-structures induced by good Borel ...
Ros, Luca Motto
core +1 more source
FEBS Open Bio, EarlyView.5‐Aminolevulinic acid combined with ferric ammonium citrate (5‐ALA/FAC) stimulates dermal papilla cell activity and promotes hair follicle growth. The treatment enhances ERK and AKT signaling, increases hair‐inductive gene expression, and restores dermal papilla function suppressed by dihydrotestosterone and oxidative stress, resulting in enhanced hair
Han‐Wook Ryu, Eok‐Soo Oh, Sewoon Kim
wiley +1 more source