Results 141 to 150 of about 27,657 (222)

Effect of rosiglitazone on 3T3-L1 adipocyte formation

, 2002
Rosiglitazone is a current Type 2 diabetes drug. Two theories about rosiglitazone's therapeutic mechanism are: new insulin responsive adipocytes form, or that pre-existing insulin-resistant adipocytes improve.
Burkart, Alison Marie
core  

Rosiglitazone RECORD study: Glucose control outcomes at 18 months

Aims: To compare glucose control over 18 months between rosiglitazone oral combination therapy and combination metformin and sulphonylurea in people with Type 2 diabetes.
Gomis R, Jones NP, Pocock SJ, Hanefeld M, Curtis P, Home PD, Beck-Nielsen H, Komajda M   +7 more
core  

Rosiglitazone improves stallion sperm motility, ATP content, and mitochondrial function

Media used for equine sperm storage often contain relatively high concentrations of glucose, even though stallion spermatozoa preferentially utilize oxidative phosphorylation (OXPHOS) over glycolysis to generate ATP and support motility. Rosiglitazone is
Zamira Gibb (21133859), Robert Aitken (21136145), Aleona Swegen (21139979), Sarah Lambourne (21134399)   +3 more
core  

The rosiglitazone decision process at FDA and EMA. What should we learn?

, 2013
The rosiglitazone decision process at FDA and EMA. What should we learn? In September 2010 the EMA decided to suspend the market authorisation of rosiglitazone while the FDA decided to restrict its use.
Pouwels, Koen, Van Grootheest, Kees
core  

Transient SUMOylation inhibition in human pre-adipocytes stably imprints a transcriptional beiging fate. [PDF]

Nucleic Acids Res
Nothnagel PMC, Meslin PA, Wik JA, Dufour D, Strøm YE, Bjørås M, Enserink JM, Skålhegg BS, Briand N, Mathelier A, Chymkowitch P.   +10 more
europepmc   +1 more source

Bayesian Random-Effects Meta-Analysis of Aggregate Data on Clinical Events. [PDF]

Stat Med
Röver C, Wu Q, Loos A, Friede T.
europepmc   +1 more source

Discovery of novel quinazoline-sulfonamide derivatives with promising antidiabetic activity. [PDF]

Front Chem
Zayed MF, Muhammad Y, Alqurain AA, Banafa MAA, Omar AM.   +4 more
europepmc   +1 more source

PPARγ contributes to cardioprotection against heat stroke through ABCC5-dependent lipid metabolism. [PDF]

Redox Biol
Shen M, Zhao A, Hao G, Lei W, Li N, Deng C, Wang X, Chen Y, Zhang Z, Dong Y, Yang Y.   +10 more
europepmc   +1 more source

Integrated In Silico Prioritization of Antidiabetic Phytochemicals from <i>Uvaria chamae</i> P. Beauv. Based on Docking, Induced-Fit Docking, QSAR, and ADMET Analyses. [PDF]

Molecules
Sovegnon T, Fagla SM, Legba BB, Lorent J, Quetin-Leclercq J, Ganfon H, Klotoe JR, Gbaguidi F, Dougnon V.   +8 more
europepmc   +1 more source

METTL14 inhibits atherogenesis by epigenetically activating PPAR-α/γ transcription and fatty acid oxidation in VSMCs. [PDF]

Cardiovasc Res
Cui L, Ho CK, Liang P, Gao W, Liu J, Tian XY, Wong R, Zhou B, Lui KO.   +8 more
europepmc   +1 more source