Thiazolidinedione Use and Cardiovascular Outcomes in Patients With Type 2 Diabetes Who Underwent Carotid Artery Revascularization [PDF]
Journal of the American Heart Association: Cardiovascular and Cerebrovascular DiseaseBackground Thiazolidinediones are oral antidiabetic agents known for their wide‐ranging pleiotropic effects, potentially offering cardiovascular protection.
Jun Hwee Kim +6 more
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The Efficacy of Treatment Intensification by Quadruple Oral Therapy Compared to GLP-1RA Therapy in Poorly Controlled Type 2 Diabetes Mellitus Patients: A Real-world Data Study [PDF]
Diabetes & Metabolism Journal, 2023 We compared the glycemic efficacy of treatment intensification between quadruple oral antidiabetic drug therapy and once-weekly glucagon-like peptide-1 receptor agonist (GLP-1RA)-based triple therapy in patients with poorly controlled type 2 diabetes ...
Minyoung Kim +7 more
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Comparative Effects of Sodium-Glucose Cotransporter 2 Inhibitor and Thiazolidinedione Treatment on Risk of Stroke among Patients with Type 2 Diabetes Mellitus [PDF]
Diabetes & Metabolism Journal, 2022 Background Although cardiovascular outcome trials using sodium-glucose cotransporter-2 inhibitors (SGLT-2i) showed a reduction in risk of 3-point major adverse cardiovascular events (MACE), they did not demonstrate beneficial effects on stroke risk ...
Seung Eun Lee +5 more
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Treatments in Endocrinology, 2006 Our knowledge and understanding of the role played by peroxisome proliferator-activated gamma receptors in physiology and pathophysiology has expanded dramatically over the past 5 years. Originally described as having important functions in adipogenesis and glucose homeostasis, their pharmacologic agonists, the thiazolidinediones, were introduced as ...
Kathryn, Reynolds, Ronald B, Goldberg
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The Potential Roles of Post-Translational Modifications of PPARγ in Treating Diabetes
Biomolecules, 2022 The number of patients with type 2 diabetes mellitus (T2DM), which is mainly characterized by insulin resistance and insulin secretion deficiency, has been soaring in recent years.
Xiaohui Ji +6 more
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Reproductive Health, 2021 Plain English summary This study aimed to compare the effects of oral insulin sensitizers on endocrine and metabolic profiles in women with polycystic ovary syndrome (PCOS). A random-effects network meta-analysis including 22 trials was conducted.
Han Zhao +3 more
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Combination of pioglitazone and dendritic cell to optimize efficacy of immune cell therapy in CT26 tumor models [PDF]
BioImpacts, 2023 Introduction: The maturation faith of dendritic cells is restrained by the inflammatory environment and cytokines, such as interleukin-6 and its downstream component. Therefore, introducing the suitable antigen to dendritic cells is crucial.
Samaneh Tokhanbigli +4 more
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Effects of Thiazolidinedione and New Antidiabetic Agents on Stroke [PDF]
Journal of Stroke, 2019 Patients with hyperglycemia are at a high risk of cardio- and cerebrovascular diseases. Diabetes patients also have poor outcomes after cerebrovascular disease development.
Chang Ho Ahn, Soo Lim
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Metals, 2022 In the present work, we represent two thiazolidinediones, namely (Z)-5-(4-methoxybenzylidene) thiazolidine-2,4-dione (MeOTZD) and (Z)-5-(4-methylbenzylidene) thiazolidine-2,4-dione (MeTZD), as corrosion inhibitors for carbon steel (CS) in 1.0 M HCl ...
Abdelkarim Chaouiki +9 more
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Comparison of the Effects of Various Antidiabetic Medication on Bone Mineral Density in Patients with Type 2 Diabetes Mellitus [PDF]
Endocrinology and Metabolism, 2021 Background Prospective comparative studies on the effects of various antidiabetic agents on bone metabolism are limited. This study aimed to assess changes in bone mass and biochemical bone markers in postmenopausal patients with type 2 diabetes mellitus
Jeonghoon Ha +8 more
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