Results 81 to 90 of about 58,009 (170)

Human Brain Stem Structures Respond Differentially to Noxious Heat

Frontiers in Human Neuroscience, 2013
Concerning the physiological correlates of pain, the brain stem is considered to be one core region that is activated by noxious input. In animal studies, different slopes of skin heating (SSH) with noxious heat led to activation in different columns of
Alexander eRitter, Marcel eFranz, Caroline eDietrich, Wolfgang H. R. Miltner, Thomas eWeiss   +4 more
doaj   +1 more source

Molecular identification of bulbospinal ON neurons by GPER, which drives pain and morphine tolerance

The Journal of Clinical Investigation, 2023
The rostral ventromedial medulla (RVM) exerts bidirectional descending modulation of pain attributable to the activity of electrophysiologically identified pronociceptive ON and antinociceptive OFF neurons.
Yingfu Jiao, Po Gao, Li Dong, Xiaowei Ding, Youqiang Meng, Jiahong Qian, Ting Gao, Ruoxi Wang, Tao Jiang, Yunchun Zhang, Dexu Kong, Yi Wu, Sihan Chen, Saihong Xu, Dan Tang, Ping Luo, Meimei Wu, Li Meng, Daxiang Wen, Changhao Wu, Guohua Zhang, Xueyin Shi, Weifeng Yu, Weifang Rong   +23 more
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Medial lemniscus, rostral medulla

, 1997
Medial lemniscus, rostral medulla. Transverse plane.

core  

The distribution patterns of neurons in the ventromedial medulla that were retrogradely labeled from the lumbar dorsal or ventral horn.

, 2013
Drawings illustrating representative single brainstem sections of the rostral part of ventromedial medulla (RVM) and the caudal part of ventromedial medulla (CVM).
Somesh K. Kohli (324278), Mehdi Hossaini (324275), Jan C. Holstege (324281), Jacqueline A. C. Goos (324276)   +3 more
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Descending inhibitory rostral ventromedial medulla neurons cause widespread antinociception and contribute to the pain-inhibits-pain phenomenon

Nature Communications
Acute painful stimuli applied to one body site reduce pain at other sites. The circuit basis of this “pain-inhibits-pain” phenomenon, also known as diffuse noxious inhibitory control (DNIC) in animals or conditioned pain modulation (CPM) in humans, is ...
Robert P. Ganley, Marília Sousa, Guangchen Ji, Matteo Ranucci, Camilla Beccarini, Kira Werder, Francesca Pietrafesa, Simon d’Aquin, Tugce Akyüz, Michèle Hubli, Petra Schweinhardt, Volker Neugebauer, Mark A. Hoon, Hendrik Wildner, Hanns Ulrich Zeilhofer   +14 more
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Altered Brainstem Pain-Modulation Circuitry Connectivity During Spontaneous Pain Intensity Fluctuations

Journal of Pain Research, 2020
Emily P Mills,1 Zeynab Alshelh,1 Danny Kosanovic,1 Flavia Di Pietro,1 E Russell Vickers,1 Paul M Macey,2 Luke A Henderson1 1Department of Anatomy and Histology, University of Sydney, Sydney, NSW 2006, Australia; 2School of Nursing and Brain Research ...
Mills EP, Alshelh Z, Kosanovic D, Di Pietro F, Vickers ER, Macey PM, Henderson LA   +6 more
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A GABAergic Projection from the Zona Incerta to the Rostral Ventromedial Medulla Modulates Descending Control of Neuropathic Pain

Brain Sciences
Background: The rostral ventromedial medulla (RVM) is a central hub of the descending pain modulatory system, yet the inhibitory circuits that regulate its activity during neuropathic pain remain poorly defined.
Lijing Zou, Hao Ding, Yujiao Hu, Zhuo Wen, Lina Yu, Min Yan   +5 more
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Release of ATP in the ventral medulla during hypoxia in rats: role in hypoxic ventilatory response [PDF]

, 2005
P2X2 receptor subunits of the ATP-gated ion channels are expressed by physiologically identified respiratory neurons in the ventral respiratory column, implicating ATP in the control of respiratory activity.
Spyer, K. Michael, Llaudet, E, Gourine, Alexander V., Spyer, KM, Dale, Nicholas, Llaudet, Enrique, Dale, N, Gourine, AV   +7 more
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Noninvasive vagus nerve stimulation alters neural response and physiological autonomic tone to noxious thermal challenge.

PLoS ONE, 2019
The mechanisms by which noninvasive vagal nerve stimulation (nVNS) affect central and peripheral neural circuits that subserve pain and autonomic physiology are not clear, and thus remain an area of intense investigation.
Imanuel Lerman, Bryan Davis, Mingxiong Huang, Charles Huang, Linda Sorkin, James Proudfoot, Edward Zhong, Donald Kimball, Ramesh Rao, Bruce Simon, Andrea Spadoni, Irina Strigo, Dewleen G Baker, Alan N Simmons   +13 more
doaj   +1 more source

Periaqueductal gray neurons project to spinally projecting GABAergic neurons in the rostral ventromedial medulla

, 2008
The analgesic effects of morphine are mediated, in part, by periaqueductal gray (PAG) neurons that project to the rostral ventromedial medulla (RVM). Although much of the neural circuitry within the RVM has been described, the relationship between RVM ...
Whittier, Kelsey L, Aicher, Sue A, Hegarty, Deborah M, Morgan, Michael M   +3 more
core   +1 more source