Results 41 to 50 of about 4,024,921 (250)
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Wilmington Rotary Club Centennial Anniversary 2015 Commemorative Plate
, 2015 Presented to the Wilmington Rotary Club by the Rotary Club of Georgetown, Guyana. The painting is of Kaieteur Falls, a national park in Guyana.
core +2 more sources
Scientific Reports, 2018 A correction to this article has been published and is linked from the HTML and PDF versions of this paper. The error has been fixed in the paper.
Yoshiaki Kinosita +2 more
doaj +1 more source
A Novel Robotic Exoskeleton for Finger Rehabilitation: Kinematics Analysis
Applied Bionics and Biomechanics, 2022 A novel robotic exoskeleton for fingers rehabilitation is developed, which is driven by linear motors through Bowden cables. For each finger, in addition to three links acting as phalanxes, two more links acting as knuckles are also implemented.
Yong Dai +3 more
doaj +1 more source
FEBS Letters, EarlyView.Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source
, 2012 A memo sent to the Toledo Rotary Club asking about the history of the Toledo Rotary ...
Toledo Rotary Club, Rotary International
core +1 more source
Advances in Electrical and Electronic Engineering, 2008 The mathematical model of cylindrical linear induction motor (C-LIM) fed via frequency converter is presented in the paper. The model was developed in order to analyze numerically the transient states.
Andrzej Rusek, Andrzej Popenda
doaj
Journal of EngineeringThe paper presented a new type of double helical-winding tubular induction motor (DHWTIM). The proposed motor consists of double- layer helical windings primary arranged on the same circumference with a common secondary.
J.H. Alwash, Saad Mahdi
doaj +1 more source
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source