Results 61 to 70 of about 271,704 (308)

Comparison of instrumentation time and cleaning efficacy of manual instrumentation, rotary systems and reciprocating systems in primary teeth: An in vitro study

Journal of Indian Society of Pedodontics and Preventive Dentistry, 2014
Background: Paediatric Endodontics is an important clinical procedure commonly used to manage pulpally involved or non-vital teeth in children. One of the important steps in root canal preparation in deciduous teeth is the removal of organic debris. Aim:
Farhin Katge, Devendra Patil, Manohar Poojari, Jitesh Pimpale, Abhinav Shitoot, Bhavesh Rusawat   +5 more
doaj   +1 more source

Randomized double-blind, placebo-controlled study of topical diclofenac in the prevention of hand-foot syndrome in patients receiving capecitabine (the D-TORCH study)

Trials, 2022
Introduction Hand-foot syndrome (HFS) is a common cutaneous side effect of capecitabine therapy. Apart from oral cyclooxygenase-2 (COX-2) inhibitor (celecoxib), there are no proven strategies for the prevention of HFS.
Akhil Santhosh, Akash Kumar, Raja Pramanik, Ajay Gogia, Chandra Prakash Prasad, Ishaan Gupta, Nishkarsh Gupta, Winson Y. Cheung, Ravindra Mohan Pandey, Atul Sharma, Atul Batra   +10 more
doaj   +1 more source

Microfluidic Rotary Pump [PDF]

, 2014
Rotary micropump is a type of micropump which consists of a rotary element used for moving fluids. Based on different design concepts, rotary micropumps make use of either viscous forces or pressure forces to carry out the pumping action.
Li, D., Çetin, Barbaros, Salemmilani, Reza   +2 more
openaire   +2 more sources

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

Clinicopathologic Characteristics and Treatment Outcomes of Patients With Up-Front Metastatic Breast Cancer: Single-Center Experience in India

Journal of Global Oncology, 2019
PURPOSE: Approximately 5% to 10% of patients with breast cancer present with up-front metastasis and carry a poor prognosis (5-year survival rates of approximately 20%).
Ajay Gogia, Suryanarayana Vishnu S. Deo, Dayanand Sharma, Sanjay Thulkar, Rakesh Kumar, Prabhat S. Malik, Sandeep Mathur   +6 more
doaj   +1 more source

In vitro expansion of fetal liver hematopoietic stem cells

Scientific Reports, 2021
Fetal liver hematopoietic stem and progenitor cells (HSPCs) have been considered appropriate for the management of aplastic anemia owing to their proliferative potential. Bone marrow recovery was possible in some cases; the engraftment potential of these
Rashmi Bhardwaj, Lalit Kumar, Deepika Chhabra, N. K. Mehra, Atul sharma, Sujata Mohanty, Vinod Kochupillai   +6 more
doaj   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

Compliance to Therapy—Elderly Head and Neck Carcinoma Patients

Canadian Geriatrics Journal, 2014
Background Treatment compliance of elderly patients to intensive multimodality cancer therapy can be challenging and has not been adequately addressed in developing countries.
Aman Sharma, Renu Madan, Rajeev Kumar, Prem Sagar, Vineet K. Kamal, Alok Thakar, Atul Sharma, Bidhu K. Mohanti   +7 more
doaj   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source