Results 91 to 100 of about 2,719,005 (328)

Targeting TNBC: core–shell polycationic polyurea dendrimers with inherent anticancer activity

FEBS Open Bio, EarlyView.
Core–shell polycationic PURE dendrimers were tested in TNBC‐derived tumor models. Both formulations selectively targeted TNBC and effectively reduced tumor volume. PUREG4‐OEI48 suppressed tumor growth without detectable toxicity, whereas PUREG4‐OCEI24, despite showing efficacy, induced hepatic toxicity.
Adriana Cruz, Bruna Abreu, Cindy Mendes, Catarina Freitas‐Dias, Filipe Gonçalves, Fernanda Silva, José Ramalho, Saudade André, Vasco D. B. Bonifácio, Jacinta Serpa   +9 more
wiley   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

FEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon, Angéla Békesi, Latifa Kazzazy, Jázmin Mihály, Máté Varga, Beáta G. Vértessy, Kinga Nyíri   +6 more
wiley   +1 more source

Differential Rotation in F Stars

, 2007
Differential rotation can be detected in single line profiles of stars rotating more rapidly than about $v \sin{i} = 10$ km s$^{-1}$ with the Fourier transform technique.
Barnes, Collier Cameron, Gray, Hünsch, Hünsch, Küker, Reiners, Reiners, Reiners, Reiners, Reiners, Reiners, Schrijver   +12 more
core   +1 more source

Shortcuts to adiabatic rotation of a two-ion chain [PDF]

, 2021
Ander Tobalina, J. G. Muga, I. Lizuain, M. Palmero   +3 more
openalex   +1 more source

Enzymatic degradation of biopolymers in amorphous and molten states: mechanisms and applications

FEBS Open Bio, EarlyView.
This review explains how polymer morphology and thermal state shape enzymatic degradation pathways, comparing amorphous and molten biopolymer structures. By integrating structure–reactivity principles with insights from thermodynamics and enzyme engineering, it highlights mechanisms that enable efficient polymer breakdown.
Anđela Pustak, Aleksandra Maršavelski
wiley   +1 more source

Unmanned Aerial Vehicle-Based Techniques for Monitoring and Prevention of Invasive Apple Snails (Pomacea canaliculata) in Rice Paddy Fields

Agriculture
The destructive impact of invasive apple snail (Pomacea canaliculata) on young rice seedlings has garnered global attention, particularly in warm regions where rice production occurs.
Senlin Guan, Kimiyasu Takahashi, Shunichiro Watanabe, Katsunori Tanaka   +3 more
doaj   +1 more source

Supernumerary teeth in the premaxillary region: its effects on the eruption and occlusion of the permanent incisors

Australasian Orthodontic Journal, 1990
The presence of supernumerary teeth in the premaxillary region may cause a variety of pathological effects. This study was carried out to determine the various aspects of supernumerary teeth in the premaxillary region, particularly the effects of the ...
Nik-Hussein Nik Noriah
doaj   +1 more source

Tumor‐stromal crosstalk and macrophage enrichment are associated with chemotherapy response in bladder cancer

FEBS Open Bio, EarlyView.
Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐
Sophie Leypold, Janik Riese, Lancelot Seillier, Mark Kühnel, Julia Pannhausen, Charlotte O. J. Fröhlich, Christian Martin, Peter Boor, Matthias Saar, Danny D. Jonigk, Nadine T. Gaisa, Michael Rose   +11 more
wiley   +1 more source

Gregory-Laflamme instability of a slowly rotating black string

, 2011
We study the Gregory-Laflamme instability of a 5-dimensional slowly rotating black string in which the 4-dimensional section is described by the Kerr black hole.
Bhattacharyya S., Caldarelli M. M., Camps J., CHUL-MOON YOO, Dias O. J., Emparan R., Emparan R., Kleihaus B., MISAO SASAKI, SUGURE TANZAWA, Thorne E.   +10 more
core   +1 more source