Results 81 to 90 of about 1,093,749 (248)

Bridging the gap: a genetically validated avian chorioallantoic membrane platform for investigation of spontaneous circulating tumor cells

Molecular Oncology, EarlyView.
We established the avian chorioallantoic membrane (CAM) assay as a scalable in vivo model for studying circulating tumor cells (CTCs). Human gastrointestinal tumors spontaneously released genetically validated CTCs that were detected across multiple platforms, demonstrating that the CAM model provides an accessible tool for investigating early cancer ...
Dennis Roth, Rui P. L. Neves, Julia Geheb, Christian Ballmeyer, Nathalie Gaßmann, Kiki C. Andree, Monica Sudarsanam, Christiane Driemel, Celine Örencik, Andrè Franken, Eslam Elmaghraby, Sven H. Loosen, Roderburg Christoph, Sebastian Schoelch, Hans Neubauer, Wolfram T. Knoefel, Nikolas H. Stoecklein, Georg Fluegen   +17 more
wiley   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

FEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

Analysis of the beneficial effects of prior soybean cultivation to the field on corn yield and soil nitrogen content

Frontiers in Plant Science
Corn-soybean rotation is a cropping pattern to optimize crop structure and improve resource use efficiency, and nitrogen (N) fertilizer application is an indispensable tool to increase corn yields.
Chao Yan, Yi Yang, Junming Song, Fuxin Shan, Xiaochen Lyu, Shuangshuang Yan, Chang Wang, Qiulai Song, Chunmei Ma   +8 more
doaj   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source

Mandatory audit firm rotation in Spain: a policy that was never applied [PDF]

In recent international debates on auditing regulation, Spain has assumed a real prominence as a claimed practical example of where a policy of mandatory audit firm rotation did not work and was duly abolished.
NIEVES CARRERA
core  

Refinement of amino‐acid conformation vs. difference density maps in time‐resolved serial femtosecond crystallography data analysis

FEBS Open Bio, EarlyView.
The dFoCC pipeline starts with observed DED and resting‐state coordinates, which are then used to generate a library of triggered states. Correlation analysis of the calculated DED features of each candidate vs observed DED permits quantitative evaluation of candidate structural quality.
Meng Iao Fong, Yuhei Hosokawa, Lars Oliver Essen, Manuel Maestre‐Reyna   +3 more
wiley   +1 more source

Modelling the Adoption of Crop Rotation Practices in Organic Mixed Farms [PDF]

Taylor et al. (2001) noted that well designed rotations are fundamental to organic farming systems. Rotations help organic systems achieve a balance between crops which deplete fertility, in particular nitrogen, and soil organic matter, and crops which ...
Revoredo-Giha, Cesar, Renwick, Alan W., Topp, Kairsty   +2 more
core  

A multi-degree-of-freedom spherical rotor piezoelectric actuator with flexible stator supports and adjustable preloading

Advances in Mechanical Engineering
Multi-degree-of-freedom spherical rotor piezoelectric actuators require multiple stators to maintain stable contact with a curved rotor, making their performance sensitive to nonuniform preload.
Jintao Wu, Chuanhu Niu, Qichong Ma, Jiyang Zhang, Song Pan   +4 more
doaj   +1 more source

Longitudinal Evaluation Of Soft Palate And Nasopharyngeal Airway Relations İn Different Rotation Types

Turkish Journal of Orthodontics, 2000
Purpose:The aim of this study was to evaluate the relationships between soft palate and nasopharyngeal airway dimensions in different mandibular rotation types.Materials and Method:A total of 72 lateral cephalograms which were obtained three periods ...
M. Okan Akçam, T. Ufuk Toygar
doaj   +1 more source