Results 71 to 80 of about 896,865 (267)

Heterotropic regulation and negative homotropic cooperativity

open access: yesFEBS Open Bio, EarlyView.
We identified a structural module common to some proteins that couple negative cooperativity with heterotropic regulation, two features that rarely coexist. These proteins are ring‐like and present an ordered asymmetry whereby noncontacting subunits are symmetric, and their tertiary structure differs from that of contacting subunits.
Veronica Morea   +5 more
wiley   +1 more source

Rotation-induced macromolecular spooling of DNA [PDF]

open access: yes, 2017
Genetic information is stored in a linear sequence of base pairs; however, thermal fluctuations and complex DNA conformations such as folds and loops make it challenging to order genomic material for in vitro analysis.
Gary W. Slater (1991002)   +7 more
core  

Rotation invariant matching of partial shoeprints [PDF]

open access: yes, 2009
In this paper, we propose a solution for the problem of rotated partial shoeprint retrieval, based on the combined use of local points of interest and SIFT descriptor. Once the generated features are encoded using SIFT descriptor, matching is carried out
Bouridane, A.   +11 more
core   +1 more source

Epilepsy‐Associated Variants of a Single SCN1A Codon Exhibit Divergent Functional Properties

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Pathogenic variants in SCN1A, which encodes the voltage‐gated sodium channel NaV1.1, are associated with multiple epilepsy syndromes exhibiting a range of clinical severity. SCN1A variants are reported in different syndromes, including Dravet syndrome, which is associated with loss‐of‐function, whereas neonatal/infantile‐onset ...
Lanie N. Liebovitz   +3 more
wiley   +1 more source

Rotation-Activity-Age Relations for Solar-Type and Cooler Stars [PDF]

open access: yes, 2016
The fact that stellar rotation and chromospheric emission are correlated with age was explicitly noted by Wilson (1963) and reinforced by Kraft (1967). Wilson knew that Ca II emission was correlated with surface magnetic field in the Sun. Skumanich (1972)
Basri, Gibor, Basri, Gibor (5201506)
core   +1 more source

Effectiveness of rTMS on Working Memory and Inhibitory Impairments in Patients With Post‐Stroke Executive Deficits

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Considerable efforts have been dedicated to developing effective treatments for post‐stroke executive impairment (PSEI), among which repetitive transcranial magnetic stimulation (rTMS) has shown great potential. This study aimed to investigate the therapeutic effects of high‐frequency rTMS on working memory (WM) and response ...
Mengting Lao   +6 more
wiley   +1 more source

Endogenous Bid Rotation in Repeated Auctions [PDF]

open access: yes
I study collusion between two bidders in a general symmetric IPV repeated auction, without communication, side transfers, or public randomization. I construct a collusive scheme, endogenous bid rotation, that generates a payoff larger than the bid ...
Rachmilevitch, Shiran
core  

Neurochemical Endpoints to Inform Early‐Stage Trials of Spinocerebellar Ataxia 2 and 3 in a Multisite Setting

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Neurochemical levels measured by brain MR spectroscopy (MRS) have been proposed as endpoints for clinical trials in early‐stage spinocerebellar ataxia (SCA) trials. We tested their trial‐readiness by quantifying neurochemicals in three affected brain regions in early‐stage cohorts of SCA2 and SCA3, examining their reproducibility in ...
James M. Joers   +19 more
wiley   +1 more source

Spatial geometry of charged rotating and non-rotating rings in rotating and non-rotating frames

open access: yes, 2016
Spatial geometry of charged thin rotating and non-rotating rings in a rotating frame is investigated. It is shown, on an example of interaction between a charged probe and two positive charged non-rotating and negative charged rotating rings that the spatial geometry of the rotating ring in the rotating frame has to be different to the spatial geometry
openaire   +2 more sources

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