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Rotavirus is the most common cause of diarrhoeal disease among infants and young children. It is a genus of double-stranded RNA viruses in the family Reoviridae. Nearly every child in the world is infected with rotavirus at least once by the age of five.
Graham Beards
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Clinical Profile and Serotyping of Rotavirus Diarrhoea in the Postvaccination Period: A Single-centre Cross-sectional Study [PDF]
Introduction: Rotavirus is the leading cause of severe, life threatening gastroenteritis in infants and young children. As rotavirus strains vary between geographic areas, region specific genotyping information is highly vital to study rotavirus ...
Gunasekaran Sabharritha+2 more
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Background G12 rotaviruses were first observed in sub-Saharan Africa in 2004 and since then have continued to emerge and spread across the continent and are reported as a significant human rotavirus genotype in several African countries, both prior to ...
Kebareng G. Rakau+6 more
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Genetic Diversity of Rotaviruses Circulating in Pediatric Patients and Domestic Animals in Thailand
Rotavirus A is a highly contagious virus that causes acute gastroenteritis in humans and a wide variety of animals. In this review, we summarized the information on rotavirus described in the studies in the last decade (2008 to 2021) in Thailand ...
Nutthawadee Jampanil+3 more
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Rotavirus, the most common diarrheal pathogen in children worldwide, causes approximately one third of diarrhea-associated hospitalizations and 800,000 deaths per year. Because natural infection reduces the incidence and severity of subsequent episodes, rotavirus diarrhea might be controlled through vaccination.
Umesh D. Parashar+3 more
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Rotavirus Vaccine Impact since Its Introduction in the National Immunization Program of Argentina
Introduction Rotavirus (RV) is the most common cause of childhood diarrhea. Argentina introduced RV vaccination in the National Immunization Program in January 2015.
Sebastian Garcia Marti+6 more
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Estimating the global impact of rotavirus vaccines on child mortality
Objectives: We estimated the global impact of rotavirus vaccines on deaths among children under five years old by year. Methods: We used a proportionate outcomes model with a finely disaggregated age structure to estimate rotavirus deaths prevented by ...
Andrew Clark+10 more
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Background: Rotavirus vaccination was introduced into the Australian National Immunisation Program in mid-2007. We aimed to assess the impact of the rotavirus vaccination program on the burden of hospitalizations associated with all-cause acute ...
Parveen Fathima+5 more
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Rotavirus and autoimmunity [PDF]
Rotavirus, a major etiological agent of acute diarrhea in children worldwide, has historically been linked to autoimmunity. In the last few years, several physiopathological approaches have been proposed to explain the leading mechanism triggering autoimmunity, from the old concept of molecular mimicry to the emerging theory of bystander activation and
Antonio Salas+3 more
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Background. The cumulative annual statistics of rotavirus-associated gastroenteritis are about 25 million outpatient visits, 2 million hospitalizations, and 180,000–450,000 deaths in children under 5 years of age.
А.А. Kleshchuk, Т.R. Kolotylo
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