ABSTRACT Favipiravir is a selective RNA polymerase inhibitor and a broad‐spectrum antiviral drug. Favipiravir reduces cell proliferation by inhibiting RNA transcription, particularly in rapidly proliferating cells such as spermatogonia. The aim of this study was to investigate the effects and mechanism of action of favipiravir (T‐705) on sperm quality ...
Ali Doğan Ömür+6 more
wiley +1 more source
Rotavirus symptomatic infection among unvaccinated and vaccinated children in Valencia, Spain
Background Human group A rotavirus is the leading cause of severe acute gastroenteritis in young children worldwide. Immunization programs have reduced the disease burden in many countries. Vaccination coverage in the Autonomous Region of Valencia, Spain,
Raúl Pérez-Ortín+5 more
doaj +1 more source
BACKGROUND Botswana introduced monovalent G1P rotavirus vaccine (RV1) in July 2012, providing one of the first opportunities to assess the effectiveness of routine RV1 vaccination in a high-burden setting in Africa.
Paul A. Gastañaduy+11 more
semanticscholar +1 more source
Advances in enteric disease vaccines: from innovation to implementation [PDF]
The Seventh International Conference on Vaccines for Enteric Diseases Bangkok, Thailand, 6–8 November 2013 Hosting 222 participants from more than 25 countries, the Seventh International Conference on Vaccines for Enteric Diseases (VED 2013) displayed ...
Parker, EPK
core +1 more source
Incidence of biliary atresia in the United States before and during the COVID‐19 pandemic
Abstract Objectives The etiology of biliary atresia (BA) is unclear and potentially involves viral triggers. We aimed to compare the incidence of BA in the United States before and during the coronavirus disease 2019 (COVID‐19) pandemic, focusing on potential associations with viral circulation disruptions caused by nonpharmaceutical interventions ...
Yasmeen Z. Qwaider+6 more
wiley +1 more source
Acute gastroenteritis associated with Rotavirus A among children less than 5 years of age in Nepal
Background Rotavirus gastroenteritis is a major public health problem in Nepal. This study was conducted to obtain information associated with Rotavirus gastroenteritis and to perform genotyping of Rotavirus A.
Sony Shrestha+5 more
doaj +1 more source
Physicochemical analysis of rotavirus segment 11 supports a 'modified panhandle' structure and not the predicted alternative tRNA-like structure (TRLS) [PDF]
.Rotaviruses are a major cause of acute gastroenteritis, which is often fatal in infants. The viral genome consists of 11 double-stranded RNA segments, but little is known about their cis-acting sequences and structural elements.
A Heerschap+47 more
core +1 more source
Infectious Diseases Surveillance System in Nigeria: Lesson From COVID‐19 Pandemic
ABSTRACT Nigeria has experienced outbreaks of multiple infectious diseases, a major public health concern, in the last 10 years, including the Ebola virus in 2014, monkeypox in 2017, COVID‐19 in 2020, Lassa fever in 2022, measles in 2023, diphtheria in 2023, and the cholera outbreak in 2024.
Tolulope Joseph Ogunniyi+3 more
wiley +1 more source
Economic Cost of Campylobacter, Norovirus and Rotavirus Disease in the United Kingdom
Objectives To estimate the annual cost to patients, the health service and society of infectious intestinal disease (IID) from Campylobacter, norovirus and rotavirus. Design Secondary data analysis. Setting The United Kingdom population, 2008–9.
C. Tam, S. O'Brien
semanticscholar +1 more source
Identification of Gastroenteric Viruses by Electron Microscopy Using Higher Order Spectral Features [PDF]
Background: Many paediatric illnesses are caused by viral agents, for example, acute gastroenteritis. Electron microscopy can provide images of viral particles and can be used to identify the agents.
Chandran, Vinod, Ong, Chien
core +2 more sources