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Rotavirus infections are a leading cause of severe, dehydrating gastroenteritis in children 200,000 deaths annually, mostly in low-income countries. Rotavirus primarily infects enterocytes and induces diarrhoea through the destruction of absorptive enterocytes (leading to malabsorption), intestinal secretion stimulated by rotavirus non-structural ...
S. Crawford+11 more
semanticscholar +4 more sources
Histo-Blood Group Antigens in Children with Symptomatic Rotavirus Infection
Group A rotaviruses are a major cause of acute gastroenteritis in children. The diversity and unequal geographical prevalence of rotavirus genotypes have been linked to histo-blood group antigens (HBGAs) in different human populations.
Raúl Pérez-Ortín+5 more
doaj +2 more sources
Candidate New Rotavirus Species in Sheltered Dogs, Hungary
We identified unusual rotavirus strains in fecal specimens from sheltered dogs in Hungary by viral metagenomics. The novel rotavirus species displayed limited genome sequence homology to representatives of the 8 rotavirus species, A–H, and qualifies as a
Eszter Mihalov-Kovács+8 more
doaj +2 more sources
Introduction: Prior to 2006, nearly every U.S. child was infected with rotavirus by 5 years of age, and rotavirus was the leading cause of severe childhood gastroenteritis.
Talia Pindyck+2 more
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Rotavirus is the most common cause of diarrhoeal disease among infants and young children. It is a genus of double-stranded RNA viruses in the family Reoviridae. Nearly every child in the world is infected with rotavirus at least once by the age of five.
Graham Beards
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Introduction: Numerous studies have shown that the oral rotavirus vaccines are less effective in infants born in low income countries compared to those born in developed countries.
Daniel E. Velasquez+2 more
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Background Rotavirus is the leading global pathogen of diarrhea-associated mortality and poses a great threat to public health in all age groups. This study aimed to explore the global burden and 30-year change patterns of rotavirus infection-associated ...
Yuxia Du+11 more
semanticscholar +1 more source
Understanding Rotavirus Vaccine Efficacy and Effectiveness in Countries with High Child Mortality
Rotavirus claims thousands of lives of children globally every year with a disproportionately high burden in low- and lower-middle income countries where access to health care is limited.
Tintu Varghese, G. Kang, A. Steele
semanticscholar +1 more source
Rotavirus, the most common diarrheal pathogen in children worldwide, causes approximately one third of diarrhea-associated hospitalizations and 800,000 deaths per year. Because natural infection reduces the incidence and severity of subsequent episodes, rotavirus diarrhea might be controlled through vaccination.
Umesh D. Parashar+3 more
openaire +3 more sources
Rotavirus in Calves and Its Zoonotic Importance
Rotavirus is a major pathogen responsible for diarrheal disease in calves, resulting in loss of productivity and economy of farmers. However, various facets of diarrheal disease caused by rotavirus in calves in the world are inadequately understood ...
Umer Seid Geletu+2 more
semanticscholar +1 more source