Results 11 to 20 of about 47,181 (147)
Nature Reviews Disease Primers, 2017 Rotavirus infections are a leading cause of severe, dehydrating gastroenteritis in children 200,000 deaths annually, mostly in low-income countries. Rotavirus primarily infects enterocytes and induces diarrhoea through the destruction of absorptive enterocytes (leading to malabsorption), intestinal secretion stimulated by rotavirus non-structural ...
S. Crawford +11 more
semanticscholar +4 more sources
Virology Journal, 2022 Background Rotavirus is the leading global pathogen of diarrhea-associated mortality and poses a great threat to public health in all age groups. This study aimed to explore the global burden and 30-year change patterns of rotavirus infection-associated ...
Yuxia Du +11 more
semanticscholar +1 more source
Understanding Rotavirus Vaccine Efficacy and Effectiveness in Countries with High Child Mortality
Vaccines, 2022 Rotavirus claims thousands of lives of children globally every year with a disproportionately high burden in low- and lower-middle income countries where access to health care is limited.
Tintu Varghese, G. Kang, A. Steele
semanticscholar +1 more source
Emerging Infectious Diseases, 1998 Rotavirus, the most common diarrheal pathogen in children worldwide, causes approximately one third of diarrhea-associated hospitalizations and 800,000 deaths per year. Because natural infection reduces the incidence and severity of subsequent episodes, rotavirus diarrhea might be controlled through vaccination.
Umesh D. Parashar +3 more
openaire +3 more sources
Rotavirus in Calves and Its Zoonotic Importance
Veterinary Medicine International, 2021 Rotavirus is a major pathogen responsible for diarrheal disease in calves, resulting in loss of productivity and economy of farmers. However, various facets of diarrheal disease caused by rotavirus in calves in the world are inadequately understood ...
Umer Seid Geletu +2 more
semanticscholar +1 more source
Journal of Infectious Diseases, 2020 Since 2006, more than 100 countries have introduced rotavirus vaccine into their immunization programs. We reviewed published data on relative reductions of rotavirus hospitalizations, acute gastroenteritis (AGE) hospitalizations, and AGE deaths among ...
Eleanor M. Burnett, U. Parashar, J. Tate
semanticscholar +1 more source
JAMA pediatrics, 2018 Importance Rotavirus infection is the global leading cause of diarrhea-associated morbidity and mortality among children younger than 5 years. Objectives To examine the extent of rotavirus infection among children younger than 5 years by country and the ...
C. Troeger +25 more
semanticscholar +1 more source
Microbiology Spectrum, 2013 ABSTRACTRotaviruses (RV) are ubiquitous, highly infectious, segmented double-stranded RNA genome viruses of importance in public health because of the severe acute gastroenteritis they cause in young children and many animal species. They are very well adapted to their host, with symptomatic and asymptomatic reinfections being virtually universal ...
Franco, Manuel A., Greenberg, Harry B.
openaire +3 more sources
Rotavirus and autoimmunity [PDF]
Journal of Infection, 2020 Rotavirus, a major etiological agent of acute diarrhea in children worldwide, has historically been linked to autoimmunity. In the last few years, several physiopathological approaches have been proposed to explain the leading mechanism triggering autoimmunity, from the old concept of molecular mimicry to the emerging theory of bystander activation and
Antonio Salas +3 more
openaire +3 more sources
Intracellular neutralisation of rotavirus by VP6-specific IgG
PLoS Pathogens, 2020 Rotavirus is a major cause of gastroenteritis in children, with infection typically inducing high levels of protective antibodies. Antibodies targeting the middle capsid protein VP6 are particularly abundant, and as VP6 is only exposed inside cells ...
S. Caddy +10 more
semanticscholar +1 more source