Results 21 to 30 of about 49,675 (180)
Glycosylation and the global virome
Molecular Ecology, Volume 32, Issue 1, Page 37-44, January 2023., 2023 Abstract The sugars that coat the outsides of viruses and host cells are key to successful disease transmission, but they remain understudied compared to other molecular features. Understanding the comparative zoology of glycosylation ‐ and harnessing it for predictive science ‐ could help close the molecular gap in zoonotic risk assessment.
Cassandra L. Pegg +4 more
wiley +1 more source
Clinical Infectious Diseases, 2016 BACKGROUND Rotavirus vaccine is recommended for routine use in all countries globally. To facilitate decision making on rotavirus vaccine adoption by countries, help donors prioritize investments in health interventions, and monitor vaccine impact, we ...
J. Tate +3 more
semanticscholar +1 more source
Медична наука України, 2023 Background. The cumulative annual statistics of rotavirus-associated gastroenteritis are about 25 million outpatient visits, 2 million hospitalizations, and 180,000–450,000 deaths in children under 5 years of age.
А.А. Kleshchuk, Т.R. Kolotylo
doaj +1 more source
Intracellular neutralisation of rotavirus by VP6-specific IgG
PLoS Pathogens, 2020 Rotavirus is a major cause of gastroenteritis in children, with infection typically inducing high levels of protective antibodies. Antibodies targeting the middle capsid protein VP6 are particularly abundant, and as VP6 is only exposed inside cells ...
S. Caddy +10 more
semanticscholar +1 more source
mBio, 2015 NF-κB plays a critical role in the induction and maintenance of innate and adaptive immune transcriptional programs. An associated inhibitor of κB protein (IκB) regulates NF-κB activation and contains a degron motif (DSGΦxS) that undergoes ...
Marco Morelli +2 more
doaj +1 more source
Human Vaccines & Immunotherapeutics, 2017 Background: Maternal antibodies, acquired passively via placenta and/or breast milk, may contribute to the reduced efficacy of oral rotavirus vaccines observed in children in developing countries.
Mee-Yew Chen +9 more
doaj +1 more source
Virology Journal, 2018 Background Rotavirus infection is the most common cause of severe gastroenteritis in children under five years of age in both developed and developing countries.
Catherine Boni-cisse +6 more
doaj +1 more source
Global Illness and Deaths Caused by Rotavirus Disease in Children
Emerging Infectious Diseases, 2003 To estimate the global illness and deaths caused by rotavirus disease, we reviewed studies published from 1986 to 2000 on deaths caused by diarrhea and on rotavirus infections in children.
U. Parashar +4 more
semanticscholar +1 more source
Safety and efficacy of a pentavalent human-bovine (WC3) reassortant rotavirus vaccine.
New England Journal of Medicine, 2006 BACKGROUND Rotavirus is a leading cause of childhood gastroenteritis and death worldwide. METHODS We studied healthy infants approximately 6 to 12 weeks old who were randomly assigned to receive three oral doses of live pentavalent human-bovine (WC3 ...
T. Vesikari +27 more
semanticscholar +1 more source
Zoonoses, 2023 Acute gastroenteritis (AGE) induced by rotavirus has been a major disease burden in Egypt since 1981 when rotavirus was first reported in humans and calves.
Ahmed H. Ghonaim +5 more
doaj +1 more source