Results 21 to 30 of about 47,181 (147)

Histo-Blood Group Antigens in Children with Symptomatic Rotavirus Infection

Viruses, 2019
Group A rotaviruses are a major cause of acute gastroenteritis in children. The diversity and unequal geographical prevalence of rotavirus genotypes have been linked to histo-blood group antigens (HBGAs) in different human populations.
Raúl Pérez-Ortín, Susana Vila-Vicent, N. Carmona-Vicente, Cristina Santiso-Bellón, J. Rodríguez-Díaz, J. Buesa   +5 more
semanticscholar   +1 more source

A decade of experience with rotavirus vaccination in the United States – vaccine uptake, effectiveness, and impact

Expert Review of Vaccines, 2018
Introduction: Prior to 2006, nearly every U.S. child was infected with rotavirus by 5 years of age, and rotavirus was the leading cause of severe childhood gastroenteritis.
T. Pindyck, J. Tate, U. Parashar
semanticscholar   +1 more source

Rotavirus Vaccines

Indian Journal of Medical Microbiology, 2006
Rotavirus, the most common cause of severe diarrhea and a leading cause of mortality in children, has been a priority target for vaccine development for the past several years. The first rotavirus vaccine licensed in the United States was withdrawn because of an association of the vaccine with intussusception.
openaire   +2 more sources

Exopolysaccharide from Lactobacillus plantarum LRCC5310 offers protection against rotavirus-induced diarrhea and regulates inflammatory response.

Journal of Dairy Science, 2018
We aimed to determine the effects of Lactobacillus strains against rotaviral infections. Rotaviruses are the major causative agent of acute gastroenteritis in infants and children worldwide. However, to date, no specific antiviral drugs for the treatment
Kiyoung Kim, Gye-Nam Lee, Hien Dang Thanh, Jong-Hwa Kim, Maytiya Konkit, Seokmin Yoon, Mi-ri Park, Siyoung Yang, E. Park, Wonyong Kim   +9 more
semanticscholar   +1 more source

Differences of Rotavirus Vaccine Effectiveness by Country: Likely Causes and Contributing Factors

Pathogens, 2017
Rotaviruses are a major cause of acute gastroenteritis in infants and young children worldwide and in many other mammalian and avian host species. Since 2006, two live-attenuated rotavirus vaccines, Rotarix® and RotaTeq®, have been licensed in >100 ...
U. Desselberger
semanticscholar   +1 more source

Rotavirus genotypes in Malaysia and Universal rotavirus vaccination [PDF]

Human Vaccines & Immunotherapeutics, 2012
Group A rotavirus (RV-A) genotypes isolated in Malaysia was studied to estimate the effectiveness of a universal RV-A vaccination in Malaysia. A simple mathematical model was used, with input from a two-year, two-center, prospective study on hospitalization of RV-A gastroenteritis (RVGE) in young children, published data on RV-A hospitalizations and ...
Lee, Way Seah, Lim, B.T.Y., Chai, P.F., Kirkwood, C.D., Lee, J.K.F.   +4 more
openaire   +3 more sources

Rotavirus infection and the current status of rotavirus vaccines

Journal of the Formosan Medical Association, 2012
Among children, rotaviruses are the most common cause of severe gastroenteritis worldwide and of diarrheal deaths in developing countries. Current vaccines (e.g., Rotarix, GlaxoSmithKline Biologicals; RotaTeq, Merck and Company) effectively reduce rotaviral gastroenteritis, emergency department visits, and hospitalizations.
Lia-Beng Tan, Li-Min Huang, Shou-Chien Chen, Kow-Tong Chen   +3 more
openaire   +4 more sources

Etiology of Severe Acute Watery Diarrhea in Children in the Global Rotavirus Surveillance Network Using Quantitative Polymerase Chain Reaction

Journal of Infectious Diseases, 2017
Summary We calculated pathogen-specific attributable fractions of acute watery diarrhea in children from 16 countries using quantitative polymerase chain reaction testing for a broad range of enteropathogens.
D. Operario, J. Platts-Mills, S. Nadan, N. Page, M. Seheri, J. Mphahlele, Ira Praharaj, G. Kang, I. T. Araújo, J. Leite, D. Cowley, Sarah R. Thomas, C. Kirkwood, F. Dennis, G. Armah, J. Mwenda, P. Wijesinghe, G. Rey, Varja Grabovac, C. Berejena, Chibumbya J Simwaka, J. Uwimana, J. Sherchand, H. M. Thu, G. Galagoda, I. Bonkoungou, Sheriffo Jagne, E. Tsolenyanu, A. Diop, C. Enweronu-Laryea, Sam-Aliyah Borbor, Jieng-Lung Liu, T. McMurry, B. Lopman, U. Parashar, J. Gentsch, A. Steele, A. Cohen, F. Serhan, E. Houpt   +39 more
semanticscholar   +1 more source

Estimating global, regional and national rotavirus deaths in children aged <5 years: Current approaches, new analyses and proposed improvements

PLoS ONE, 2017
Background Rotavirus is a leading cause of diarrhoeal mortality in children but there is considerable disagreement about how many deaths occur each year.
A. Clark, R. Black, J. Tate, Anna Roose, K. Kotloff, Diana Lam, W. Blackwelder, U. Parashar, C. Lanata, G. Kang, C. Troeger, J. Platts-Mills, A. Mokdad, C. Sanderson, L. Lamberti, M. Levine, M. Santosham, D. Steele   +17 more
semanticscholar   +1 more source

Population Impact and Effectiveness of Monovalent Rotavirus Vaccination in Urban Malawian Children 3 Years After Vaccine Introduction: Ecological and Case-Control Analyses

Clinical Infectious Diseases, 2016
Background. Rotavirus vaccines have been introduced in many low-income African countries including Malawi in 2012. Despite early evidence of vaccine impact, determining persistence of protection beyond infancy, the utility of the vaccine against specific
N. Bar-Zeev, K. Jere, A. Bennett, L. Pollock, J. Tate, O. Nakagomi, M. Iturriza-Gómara, A. Costello, C. Mwansambo, U. Parashar, R. Heyderman, N. French, N. Cunliffe   +12 more
semanticscholar   +1 more source