Results 51 to 60 of about 49,675 (180)

Estimating the global impact of rotavirus vaccines on child mortality

International Journal of Infectious Diseases, 2023
Objectives: We estimated the global impact of rotavirus vaccines on deaths among children under five years old by year. Methods: We used a proportionate outcomes model with a finely disaggregated age structure to estimate rotavirus deaths prevented by ...
Andrew Clark, Sarwat Mahmud, Frederic Debellut, Clint Pecenka, Mark Jit, Jamie Perin, Jacqueline Tate, Heidi M. Soeters, Robert E. Black, Mathuram Santosham, Colin Sanderson   +10 more
doaj  

Rotavirus genotypes in children under five years hospitalized with diarrhea in low and middle-income countries: Results from the WHO-coordinated Global Rotavirus Surveillance Network.

PLOS Global Public Health, 2023
Rotavirus is the most common pathogen causing pediatric diarrhea and an important cause of morbidity and mortality in low- and middle-income countries.
Sebastien Antoni, Tomoka Nakamura, Adam L Cohen, Jason M Mwenda, Goitom Weldegebriel, Joseph N M Biey, Keith Shaba, Gloria Rey-Benito, Lucia Helena de Oliveira, Maria Tereza da Costa Oliveira, Claudia Ortiz, Amany Ghoniem, Kamal Fahmy, Hossam A Ashmony, Dovile Videbaek, Danni Daniels, Roberta Pastore, Simarjit Singh, Emmanuel Tondo, Jayantha B L Liyanage, Mohammed Sharifuzzaman, Varja Grabovac, Nyambat Batmunkh, Josephine Logronio, George Armah, Francis E Dennis, Mapaseka Seheri, Nonkululeko Magagula, Jeffrey Mphahlele, Jose Paulo G Leite, Irene T Araujo, Tulio M Fumian, Hanan El Mohammady, Galina Semeiko, Elena Samoilovich, Sidhartha Giri, Gagandeep Kang, Sarah Thomas, Julie Bines, Carl D Kirkwood, Na Liu, Deog-Yong Lee, Mirren Iturriza-Gomara, Nicola Anne Page, Mathew D Esona, M Leanne Ward, Courtnee N Wright, Slavica Mijatovic-Rustempasic, Jacqueline E Tate, Umesh D Parashar, Jon Gentsch, Michael D Bowen, Fatima Serhan   +52 more
doaj   +1 more source

Process intensification of the baculovirus expression vector system using a perfusion process with a low multiplicity of infection at high cell concentrations

Biotechnology Progress, EarlyView.
Abstract The emergence of new viruses and the spread of existing pathogens necessitate efficient vaccine production methods. The baculovirus expression vector system (BEVS) is an efficient and scalable system for subunit and virus‐like particle vaccine production and gene therapy vectors.
Jort J. Altenburg, Brenda E. Juarez‐Garza, Jelle van Keimpema, Linda van Oosten, Gorben P. Pijlman, Monique M. van Oers, René H. Wijffels, Dirk E. Martens   +7 more
wiley   +1 more source

Staphylococcus Aureus AgrA Modulators from South African Antimicrobial Plants.

Chemistry &Biodiversity, Accepted Article.
South African plants are an underutilized metabolites source for novel antimicrobials targeting key quorum sensing (QS) systems like the Staphylococcus aureus AgrA. AgrA modulating metabolites constitute a new approach to reducing resistance development.
Christiana Eleojo Aruwa, Saheed Sabiu
wiley   +1 more source

Efficacy of a Low‐Cost, Heat‐Stable Oral Rotavirus Vaccine in Niger

New England Journal of Medicine, 2017
BACKGROUND Each year, rotavirus gastroenteritis is responsible for about 37% of deaths from diarrhea among children younger than 5 years of age worldwide, with a disproportionate effect in sub‐Saharan Africa.
Sheila Isanaka, O. Guindo, C. Langendorf, A. M. Seck, B. Plikaytis, Nathan Sayinzoga-Makombe, M. McNeal, N. Meyer, E. Adehossi, A. Djibo, B. Jochum, R. Grais   +11 more
semanticscholar   +1 more source

Deployment of Rotavirus Vaccine in Western Kenya Coincides with a Reduction in All-Cause Child Mortality: A Retrospective Cohort Study

Vaccines, 2023
Rotavirus is an important cause of fatal pediatric diarrhea worldwide. Many national immunization programs began adding rotavirus vaccine following a 2009 World Health Organization recommendation.
Peter Sifuna, Andrea V. Shaw, Tina Lucas, Bernards Ogutu, Walter Otieno, David A. Larsen   +5 more
doaj   +1 more source

A novel genotyping system based on site polymorphism on spike gene reveals the evolutionary pathway of porcine epidemic diarrhea virus

iMetaOmics, EarlyView.
This study focuses on porcine epidemic diarrhea virus (PEDV), a highly virulent and rapidly evolving coronavirus threatening global swine production. We established a novel genotype system of PEDV targeting site‐specific polymorphisms in the spike (S) protein.
Mingkai Lei, Huimin Li, Xiaoyu Chen, Xiaozhen Li, Xuexiang Yu, Shengnan Ruan, Hao Wu, Ahmed H. Ghonaim, Ziyang Yan, Wentao Li, Qigai He   +10 more
wiley   +1 more source

Study the Distribution of Rotavirus Genotypes in Vaccinated and non Vaccinated Children in Babylon Province

Iraqi Journal of Pharmaceutical Sciences, 2021
Rotaviruses, a major cause of gastroenteritis in children worldwide accounts for around half a million deaths annually. Vaccine against the virus has been recommended by the WHO to be involved in the national immunization program.To evaluate the genetic ...
Qassim Mahdi Mutlak, Manal Khalid Abdulridha, Laith M Abbas Al-Huseini   +2 more
doaj   +1 more source

A marginal moment matching approach for fitting endemic-epidemic models to underreported disease surveillance counts [PDF]

arXiv, 2020
Count data are often subject to underreporting, especially in infectious disease surveillance. We propose an approximate maximum likelihood method to fit count time series models from the endemic-epidemic class to underreported data. The approach is based on marginal moment matching where underreported processes are approximated through completely ...
arxiv  

Incidence of biliary atresia in the United States before and during the COVID‐19 pandemic

Journal of Pediatric Gastroenterology and Nutrition, EarlyView.
Abstract Objectives The etiology of biliary atresia (BA) is unclear and potentially involves viral triggers. We aimed to compare the incidence of BA in the United States before and during the coronavirus disease 2019 (COVID‐19) pandemic, focusing on potential associations with viral circulation disruptions caused by nonpharmaceutical interventions ...
Yasmeen Z. Qwaider, Justin Z. Amarin, Andrew J. Spieker, Haya Hayek, James D. Chappell, Natasha B. Halasa, Harold N. Lovvorn 3rd   +6 more
wiley   +1 more source