Results 71 to 80 of about 135,736 (315)

Impact of Interleukin‐1 Blockade on the Development of Macrophage Activation Syndrome in Still's Disease: Incidence and Diagnostic Validity of the EULAR/ACR/PRINTO 2016 MAS Classification Criteria

Arthritis &Rheumatology, Accepted Article.
Objective To evaluate the applicability of the 2016 EULAR/ACR/PRINTO macrophage activation syndrome (MAS) classification criteria in patients with Still's disease (sJIA‐SD) treated with IL‐1‐targeted therapy and to assess the incidence of MAS in this context.
Remco G.A. Erkens, Greta Rogani, Laura Huber, Anouk Verwoerd, Dieneke Schonenberg‐Meinema, J. Merlijn van den Berg, Wineke Armbrust, G. Elizabeth Legger, Sylvia Kamphuis, Ellen J.H. Schatorjé, Esther P.A.H. Hoppenreijs, Joost F. Swart, Marc H.A. Jansen, Jorg van Loosdregt, Sebastiaan J. Vastert   +14 more
wiley   +1 more source

Transformative Approaches in Transitioning to a Circular Sanitation Bioeconomy in South Africa: A Scoping Review

Business Strategy and the Environment, EarlyView.
ABSTRACT Transitioning from linear flow resource management practices to a circular sanitation bioeconomy needs a transformative approach. In South Africa, the management of human excreta through resource recovery and reuse (RRR) has been widely researched and piloted.
William Musazura, Alfred Oduor Odindo, Stephen O. Ojwach   +2 more
wiley   +1 more source

Deployment of Rotavirus Vaccine in Western Kenya Coincides with a Reduction in All-Cause Child Mortality: A Retrospective Cohort Study

Vaccines, 2023
Rotavirus is an important cause of fatal pediatric diarrhea worldwide. Many national immunization programs began adding rotavirus vaccine following a 2009 World Health Organization recommendation.
Peter Sifuna, Andrea V. Shaw, Tina Lucas, Bernards Ogutu, Walter Otieno, David A. Larsen   +5 more
doaj   +1 more source

Improving rotavirus vaccine coverage: Can newer-generation and locally produced vaccines help?

Human Vaccines & Immunotherapeutics, 2018
There are two internationally available WHO-prequalified oral rotavirus vaccines (Rotarix and RotaTeq), two rotavirus vaccines licensed in India (Rotavac and Rotasiil), one in China (Lanzhou lamb rotavirus vaccine) and one in Vietnam (Rotavin-M1), and ...
Jacqueline Deen, Anna Lena Lopez, Suman Kanungo, Xuan-Yi Wang, Dang Duc Anh, Milagritos Tapia, Rebecca F. Grais   +6 more
doaj   +1 more source

Rotavirus antigenemia in children is associated with viremia.

PLoS Medicine, 2007
BackgroundAntigenemia is commonly detected in rotavirus-infected children. Although rotavirus RNA has been detected in serum, definitive proof of rotavirus viremia has not been shown.
Sarah E Blutt, David O Matson, Sue E Crawford, Mary Allen Staat, Parvin Azimi, Berkeley L Bennett, Pedro A Piedra, Margaret E Conner   +7 more
doaj   +1 more source

Study the Distribution of Rotavirus Genotypes in Vaccinated and non Vaccinated Children in Babylon Province

Iraqi Journal of Pharmaceutical Sciences, 2021
Rotaviruses, a major cause of gastroenteritis in children worldwide accounts for around half a million deaths annually. Vaccine against the virus has been recommended by the WHO to be involved in the national immunization program.To evaluate the genetic ...
Qassim Mahdi Mutlak, Manal Khalid Abdulridha, Laith M Abbas Al-Huseini   +2 more
doaj   +1 more source

A gut microbiota‐bile acid axis inhibits the infection of an emerging coronavirus by targeting its cellular receptor aminopeptidase N

iMeta, EarlyView.
Bacteroides fragilis employs bile salt hydrolase to reprogram host bile acid metabolism, generating lithocholic acid that directly blocks porcine deltacoronavirus infection by disrupting spike protein‐aminopeptidase N binding, defining a microbiota‐bile acid antiviral axis with therapeutic potential against coronaviruses.
Ya‐Qing Zhang, Bin Wang, Yong‐Le Yang, Jin‐Xin Meng, Meng‐Di Zhang, Yi‐Ke Li, Bo Dong, Yanan Zhang, Bo‐Wen Liu, Dong Yang, Chun‐Miao Ji, Yao‐Wei Huang, Shu Jeffrey Zhu   +12 more
wiley   +1 more source

Preclinical and clinical development of preventive rotavirus vaccines: special considerations

Биопрепараты: Профилактика, диагностика, лечение
INTRODUCTION. Vaccination is recognised as the only effective method for preventing rotavirus disease. Rotavirus remains a leading cause of death in young children, mainly, in developing countries.
A. S. Korovkin, D. V. Gorenkov, A. A. Soldatov, V. A. Merkulov   +3 more
doaj   +1 more source

Exopolysaccharide from Lactobacillus plantarum LRCC5310 offers protection against rotavirus-induced diarrhea and regulates inflammatory response.

Journal of Dairy Science, 2018
We aimed to determine the effects of Lactobacillus strains against rotaviral infections. Rotaviruses are the major causative agent of acute gastroenteritis in infants and children worldwide. However, to date, no specific antiviral drugs for the treatment
Kiyoung Kim, Gye-Nam Lee, Hien Dang Thanh, Jong-Hwa Kim, Maytiya Konkit, Seokmin Yoon, Mi-ri Park, Siyoung Yang, E. Park, Wonyong Kim   +9 more
semanticscholar   +1 more source

Rotavirus Vaccines

Indian Journal of Medical Microbiology, 2006
Rotavirus, the most common cause of severe diarrhea and a leading cause of mortality in children, has been a priority target for vaccine development for the past several years. The first rotavirus vaccine licensed in the United States was withdrawn because of an association of the vaccine with intussusception.
openaire   +2 more sources