Results 21 to 30 of about 40,091 (215)
International Journal of Infectious Diseases, 2021 Objectives: The introduction of the rotavirus vaccine in 2006 significantly reduced childhood incidence of acute gastroenteritis (AGE) worldwide. The rotavirus vaccine was included in Poland’s national immunization program in 2021.
Kacper Toczylowski +5 more
doaj +1 more source
iScience, 2022 Summary: Non-replicating rotavirus vaccines are an alternative strategy to improve the efficacy and safety of rotavirus vaccines. The spike protein VP4, which could be enzymatically cleaved into VP8∗ and VP5∗, is an ideal target for the development of ...
Guoxing Luo +11 more
doaj +1 more source
Indian Journal of Medical Microbiology, 2006 Rotavirus, the most common cause of severe diarrhea and a leading cause of mortality in children, has been a priority target for vaccine development for the past several years. The first rotavirus vaccine licensed in the United States was withdrawn because of an association of the vaccine with intussusception.
openaire +3 more sources
Rotavirus vaccine and health-care utilization for rotavirus gastroenteritis in Tsu City, Japan
Western Pacific Surveillance and Response, 2016 Background: Rotavirus vaccines were introduced in Japan in November 2011. We evaluated the subsequent reduction of the health-care burden of rotavirus gastroenteritis.
Kazutoyo Asada +13 more
doaj +1 more source
Vaccines, 2023 Live-attenuated, oral rotavirus vaccines have significantly reduced rotavirus-associated diarrhoea morbidity and infant mortality. However, vaccine immunogenicity is diminished in low-income countries.
Adriace Chauwa +12 more
doaj +1 more source
Recombinant monovalent llama-derived antibody fragments (VHH) to rotavirus VP6 protect neonatal gnotobiotic piglets against human rotavirus-induced diarrhea [PDF]
, 2013 Group A Rotavirus (RVA) is the leading cause of severe diarrhea in children. The aims of the present study were to determine the neutralizing activity of VP6-specific llama-derived single domain nanoantibodies (VHH nanoAbs) against different RVA strains ...
Alvarado, Carmen +14 more
core +3 more sources
Expert Review of Vaccines, 2018 Introduction: Prior to 2006, nearly every U.S. child was infected with rotavirus by 5 years of age, and rotavirus was the leading cause of severe childhood gastroenteritis.
Talia Pindyck +2 more
doaj +1 more source
Journal of Public Health in Africa, 2021 Background: Diarrheal diseases due to rotavirus infection contribute greatly to morbidity and mortality rates of babies and young children in many developing countries.
Emmanuel Magesa +2 more
doaj +1 more source
Rotavirus vaccine and diarrhea mortality: quantifying regional variation in effect size
BMC Public Health, 2011 Background Diarrhea mortality remains a leading cause of child death and rotavirus vaccine an effective tool for preventing severe rotavirus diarrhea. New data suggest vaccine efficacy may vary by region.
Black Robert E, Fischer Walker Christa L
doaj +1 more source
The laboratory test procedure to confirm rotavirus vaccine infection in severe complex immunodeficiency patients [PDF]
Osong Public Health and Research Perspectives, 2021 The rotavirus vaccine is a live vaccine, and there is a possibility of infection by the virus strain used in the vaccine. We investigated the process of determining whether an infection was caused by the vaccine strain in a severe complex ...
Su-Jin Chae +4 more
doaj +1 more source