Results 31 to 40 of about 696,003 (270)

Genotype Diversity before and after the Introduction of a Rotavirus Vaccine into the National Immunisation Program in Fiji

open access: yesPathogens, 2021
The introduction of the rotavirus vaccine, Rotarix, into the Fiji National Immunisation Program in 2012 has reduced the burden of rotavirus disease and hospitalisations in children less than 5 years of age.
Sarah Thomas   +11 more
doaj   +1 more source

Epidemiology of rotavirus diarrhea among children less than 5 years hospitalized with acute gastroenteritis prior to rotavirus vaccine introduction in India

open access: yesVaccine, 2020
Background Rotavirus is an important cause of severe diarrhea requiring hospitalization, accounting for approximately 78,000 deaths annually in Indian children below 5 years of age.
C. G. Girish Kumar   +15 more
semanticscholar   +1 more source

The Challenges and Opportunities of Next-Generation Rotavirus Vaccines: Summary of an Expert Meeting with Vaccine Developers

open access: yesViruses, 2022
The 2nd Next Generation Rotavirus Vaccine Developers Meeting, sponsored by PATH and the Bill and Melinda Gates Foundation, was held in London, UK (7–8 June 2022), and attended by vaccine developers and researchers to discuss advancements in the ...
Jessie Y.C. Chen   +6 more
semanticscholar   +1 more source

Temporal decline in diarrhea episodes and mortality in Kiribati children two years following rotavirus vaccine introduction, despite high malnutrition rates: a retrospective review

open access: yesBMC Infectious Diseases, 2020
Background Kiribati introduced rotavirus vaccine in 2015. To estimate the impact of rotavirus vaccine on acute gastroenteritis (AGE) and severe acute malnutrition (SAM) among children under 5 in Kiribati, a retrospective review of inpatient and ...
Jana Lai   +16 more
doaj   +1 more source

Efficacy, immunogenicity and safety of a trivalent live human-lamb reassortant rotavirus vaccine (LLR3) in healthy Chinese infants: A randomized, double-blind, placebo-controlled trial.

open access: yesVaccine, 2020
BACKGROUND A randomized, double-blind, placebo-controlled multicenter trial was conducted in healthy Chinese infants to assess the efficacy, immunogenicity and safety of a novel trivalent live human-lamb reassortant rotavirus vaccine (LLR3) against ...
Shengli Xia   +13 more
semanticscholar   +1 more source

Incidence and clinical characteristics of group A rotavirus infections among children admitted to hospital in Kilifi, Kenya [PDF]

open access: yes, 2008
Background Rotavirus, predominantly of group A, is a major cause of severe diarrhoea worldwide, with the greatest burden falling on young children living in less-developed countries.
Peenze, Ina   +39 more
core   +1 more source

Effects of rotavirus NSP4 protein on the immune response and protection of the SR69A-VP8* nanoparticle rotavirus vaccine

open access: yesVaccine, 2020
Rotavirus causes severe diarrhea and dehydration in young children. Even with the implementation of the current live vaccines, rotavirus infections still cause significant mortality and morbidity, indicating a need for new rotavirus vaccines with ...
Cunbao Liu   +6 more
semanticscholar   +1 more source

Household Transmission of Rotavirus in a Community with Rotavirus Vaccination in Quininde, Ecuador [PDF]

open access: yes, 2013
Background: We studied the transmission of rotavirus infection in households in peri-urban Ecuador in the vaccination era. Methods: Stool samples were collected from household contacts of child rotavirus cases, diarrhea controls and healthy controls ...
Martha Chico   +67 more
core   +1 more source

Rotaviruses and rotavirus vaccines [PDF]

open access: yesBritish Medical Bulletin, 2009
Rotaviruses (RVs) are an important cause of acute gastroenteritis in infants and young children worldwide, resulting in more than 600 000 deaths per annum, mainly in developing countries. Since the 1980s, there has been intensive research on the development of RV vaccine candidates, and since 2006 two vaccines have been licensed in many countries.The ...
Desselberger, Ulrich   +5 more
openaire   +2 more sources

Rotavirus vaccine effectiveness and impact in Uzbekistan, the first country to introduce in central Asia

open access: yesHuman Vaccines & Immunotherapeutics, 2021
Uzbekistan, the most populous country in central Asia, was the first in the region to introduce rotavirus vaccine into its national immunization program.
Umid Eraliev   +21 more
doaj   +1 more source

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