Results 41 to 50 of about 696,003 (270)

Rotavirus genetic diversity, disease association, and temporal change in hospitalized rural Kenyan children [PDF]

, 2010
Background. The effectiveness of rotavirus vaccines will be dependent on the immunity conferred against prevalent and emergent variants causing severe diarrheal disease.
Peenze, Ina, Williams, Thomas N., Peenze, I, Netshifhefhe, Lufuno, Seheri, Mapaseka, De Beer, MC, Nokes, D. James, Nokes, DJ, Seheri, M, Steele, D, De Beer, Mariet C., Williams, TN, Netshifhefhe, L, Williams, Thomas, Page, N, De Beer, De, Abwao, J, Abwao, John, Page, Nicola, Steele, Duncan   +19 more
core   +1 more source

Sensitive detection systems for infectious agents in xenotransplantation*

Xenotransplantation, EarlyView., 2020
Abstract Xenotransplantation of pig cells, tissues, or organs may be associated with transmission of porcine microorganisms, first of all of viruses, to the transplant recipient, potentially inducing a disease (zoonosis). I would like to define detection systems as the complex of sample generation, sample preparation, sample origin, time of sampling ...
Joachim Denner
wiley   +1 more source

Development of a bivalent conjugate vaccine candidate against rotaviral diarrhea and tuberculosis using polysaccharide from Mycobacterium tuberculosis conjugated to ΔVP8* protein from rotavirus

, 2021
Conjugation of carbohydrate antigens with a carrier protein is a clinically proven strategy to overcome the poor immunogenicity of bacterial polysaccharide.
조상래
core   +1 more source

Rotavirus specific maternal antibodies and immune response to RV3-BB neonatal rotavirus vaccine in New Zealand

Human Vaccines & Immunotherapeutics, 2017
Background: Maternal antibodies, acquired passively via placenta and/or breast milk, may contribute to the reduced efficacy of oral rotavirus vaccines observed in children in developing countries.
Mee-Yew Chen, Carl D. Kirkwood, Julie Bines, Daniel Cowley, Daniel Pavlic, Katherine J. Lee, Francesca Orsini, Emma Watts, Graeme Barnes, Margaret Danchin   +9 more
doaj   +1 more source

Awareness and acceptability of rotavirus vaccine among mothers of under-five children attending children outpatient clinic of ekiti state university teaching hospital

Nigerian Journal of Medicine, 2020
Background: Diarrhoea diseases remain a major contributor to infant and under-five morbidity and mortality, particularly in developing countries. Administration of the rotavirus vaccine is one of the effective measures to prevent acute and severe forms ...
A O Babatola, T O Ojo, E O Ogundare, A B Ajite, I O Oluwayemi, I Wuraola, J O Fadare, O S Olatunya   +7 more
doaj   +1 more source

Rotavirus gastroenteritis in children hospitalized in northeastern Poland in 2006–2020: Severity, seasonal trends, and impact of immunization

International Journal of Infectious Diseases, 2021
Objectives: The introduction of the rotavirus vaccine in 2006 significantly reduced childhood incidence of acute gastroenteritis (AGE) worldwide. The rotavirus vaccine was included in Poland’s national immunization program in 2021.
Kacper Toczylowski, Katarzyna Jackowska, Dawid Lewandowski, Sandra Kurylonek, Marlena Waszkiewicz-Stojda, Artur Sulik   +5 more
doaj   +1 more source

Bivalent rotavirus VP4∗ stimulates protective antibodies against common genotypes of human rotaviruses

iScience, 2022
Summary: Non-replicating rotavirus vaccines are an alternative strategy to improve the efficacy and safety of rotavirus vaccines. The spike protein VP4, which could be enzymatically cleaved into VP8∗ and VP5∗, is an ideal target for the development of ...
Guoxing Luo, Yuanjun Zeng, Han Yang, Yijian Li, Lianwei Yang, Cao Li, Feibo Song, Shiyin Zhang, Tingdong Li, Shengxiang Ge, Jun Zhang, Ningshao Xia   +11 more
doaj   +1 more source

Update on rotavirus vaccine underperformance in low- to middle-income countries and next-generation vaccines

Human Vaccines & Immunotherapeutics, 2020
In the decade since oral rotavirus vaccines (ORV) were recommended by the World Health Organization for universal inclusion in all national immunization programs, significant yet incomplete progress has been made toward reducing the burden of rotavirus ...
Benjamin Lee
semanticscholar   +1 more source

Rotavirus vaccine and health-care utilization for rotavirus gastroenteritis in Tsu City, Japan

Western Pacific Surveillance and Response, 2016
Background: Rotavirus vaccines were introduced in Japan in November 2011. We evaluated the subsequent reduction of the health-care burden of rotavirus gastroenteritis.
Kazutoyo Asada, Hajime Kamiya, Shigeru Suga, Mizuho Nagao, Ryoji Ichimi, Takao Fujisawa, Masakazu Umemoto, Takaaki Tanaka, Hiroaki Ito, Shigeki Tanaka, Masaru Ido, Koki Taniguchi, Toshiaki Ihara, Takashi Nakano   +13 more
doaj   +1 more source

Effectiveness of rotavirus vaccine in the prevention of diarrhoeal diseases among children under age five years in Kavango East and West Regions, Namibia

Journal of Public Health in Africa, 2021
Background: Diarrheal diseases due to rotavirus infection contribute greatly to morbidity and mortality rates of babies and young children in many developing countries.
Emmanuel Magesa, Marian Sankombo, Fillipine Nakakuwa   +2 more
doaj   +1 more source