Results 21 to 30 of about 40,310 (216)

Rotavirus gastroenteritis in children hospitalized in northeastern Poland in 2006–2020: Severity, seasonal trends, and impact of immunization

International Journal of Infectious Diseases, 2021
Objectives: The introduction of the rotavirus vaccine in 2006 significantly reduced childhood incidence of acute gastroenteritis (AGE) worldwide. The rotavirus vaccine was included in Poland’s national immunization program in 2021.
Kacper Toczylowski, Katarzyna Jackowska, Dawid Lewandowski, Sandra Kurylonek, Marlena Waszkiewicz-Stojda, Artur Sulik   +5 more
doaj   +1 more source

Maternal and Infant Histo-Blood Group Antigen (HBGA) Profiles and Their Influence on Oral Rotavirus Vaccine (Rotarix^TM) Immunogenicity among Infants in Zambia

Vaccines, 2023
Live-attenuated, oral rotavirus vaccines have significantly reduced rotavirus-associated diarrhoea morbidity and infant mortality. However, vaccine immunogenicity is diminished in low-income countries.
Adriace Chauwa, Samuel Bosomprah, Natasha Makabilo Laban, Bernard Phiri, Mwelwa Chibuye, Obvious Nchimunya Chilyabanyama, Sody Munsaka, Michelo Simuyandi, Innocent Mwape, Cynthia Mubanga, Masuzyo Chirwa Chobe, Caroline Chisenga, Roma Chilengi   +12 more
doaj   +1 more source

Rotavirus Vaccines

Indian Journal of Medical Microbiology, 2006
Rotavirus, the most common cause of severe diarrhea and a leading cause of mortality in children, has been a priority target for vaccine development for the past several years. The first rotavirus vaccine licensed in the United States was withdrawn because of an association of the vaccine with intussusception.
openaire   +3 more sources

Rotavirus vaccine and health-care utilization for rotavirus gastroenteritis in Tsu City, Japan

Western Pacific Surveillance and Response, 2016
Background: Rotavirus vaccines were introduced in Japan in November 2011. We evaluated the subsequent reduction of the health-care burden of rotavirus gastroenteritis.
Kazutoyo Asada, Hajime Kamiya, Shigeru Suga, Mizuho Nagao, Ryoji Ichimi, Takao Fujisawa, Masakazu Umemoto, Takaaki Tanaka, Hiroaki Ito, Shigeki Tanaka, Masaru Ido, Koki Taniguchi, Toshiaki Ihara, Takashi Nakano   +13 more
doaj   +1 more source

Bivalent rotavirus VP4∗ stimulates protective antibodies against common genotypes of human rotaviruses

iScience, 2022
Summary: Non-replicating rotavirus vaccines are an alternative strategy to improve the efficacy and safety of rotavirus vaccines. The spike protein VP4, which could be enzymatically cleaved into VP8∗ and VP5∗, is an ideal target for the development of ...
Guoxing Luo, Yuanjun Zeng, Han Yang, Yijian Li, Lianwei Yang, Cao Li, Feibo Song, Shiyin Zhang, Tingdong Li, Shengxiang Ge, Jun Zhang, Ningshao Xia   +11 more
doaj   +1 more source

A decade of experience with rotavirus vaccination in the United States – vaccine uptake, effectiveness, and impact

Expert Review of Vaccines, 2018
Introduction: Prior to 2006, nearly every U.S. child was infected with rotavirus by 5 years of age, and rotavirus was the leading cause of severe childhood gastroenteritis.
Talia Pindyck, Jacqueline E Tate, Umesh D Parashar   +2 more
doaj   +1 more source

Plant-produced viral bovine vaccines: What happened during the last ten years? [PDF]

, 2015
Vaccination has proved to be an efficient strategy to deal with viral infections in both human and animal species. However, protection of cattle against viral infections is still a major concern in veterinary science.
Dus Santos, María José, Mozgovoj, Marina Valeria, Ruiz, Vanesa, Wigdorovitz, Andrés   +3 more
core   +1 more source

Effectiveness of rotavirus vaccine in the prevention of diarrhoeal diseases among children under age five years in Kavango East and West Regions, Namibia

Journal of Public Health in Africa, 2021
Background: Diarrheal diseases due to rotavirus infection contribute greatly to morbidity and mortality rates of babies and young children in many developing countries.
Emmanuel Magesa, Marian Sankombo, Fillipine Nakakuwa   +2 more
doaj   +1 more source

Recombinant monovalent llama-derived antibody fragments (VHH) to rotavirus VP6 protect neonatal gnotobiotic piglets against human rotavirus-induced diarrhea [PDF]

, 2013
Group A Rotavirus (RVA) is the leading cause of severe diarrhea in children. The aims of the present study were to determine the neutralizing activity of VP6-specific llama-derived single domain nanoantibodies (VHH nanoAbs) against different RVA strains ...
Alvarado, Carmen, Bok, Karin, Bok, Marina, Chattha, Kuldeep S., Escribano, José M., Fernández, Fernando, Garaicoechea, Lorena Laura, Gómez Sebastián, Silvia, Lasa, Rodrigo, Nuñez, Carmen, Parreño, Gladys Viviana, Saif, Linda J., Vega, Celina Guadalupe, Vlasova, Anastasia N., Wigdorovitz, Andrés   +14 more
core   +3 more sources

Rotavirus vaccine and diarrhea mortality: quantifying regional variation in effect size

BMC Public Health, 2011
Background Diarrhea mortality remains a leading cause of child death and rotavirus vaccine an effective tool for preventing severe rotavirus diarrhea. New data suggest vaccine efficacy may vary by region.
Black Robert E, Fischer Walker Christa L
doaj   +1 more source