Results 51 to 60 of about 696,195 (244)

Preclinical and clinical development of preventive rotavirus vaccines: special considerations

Биопрепараты: Профилактика, диагностика, лечение
INTRODUCTION. Vaccination is recognised as the only effective method for preventing rotavirus disease. Rotavirus remains a leading cause of death in young children, mainly, in developing countries.
A. S. Korovkin, D. V. Gorenkov, A. A. Soldatov, V. A. Merkulov   +3 more
doaj   +1 more source

The importance of recent infection with Mycobacterium tuberculosis in an area with high HIV prevalence: a long-term molecular epidemiological study in Northern Malawi.

, 2005
BACKGROUND: The proportion of cases of tuberculosis due to recent infection can be estimated in long-term population-based studies using molecular techniques.
Crampin, Amelia C, Drobniewski, Francis, Fine, Paul EM, Glynn, Judith R, Mwaungulu, Frank D, Ndlovu, Richard, Ngwira, Bagrey M, Traore, Hamidou, Yates, Malcolm D   +8 more
core   +1 more source

Mucosal delivery of tuberculosis vaccines: a review of current approaches and challenges. [PDF]

, 2019
Introduction: Tuberculosis (TB) remains a major health threat and it is now clear that the current vaccine, BCG, is unable to arrest the global TB epidemic. A new vaccine is needed to either replace or boost BCG so that a better level of protection could
Barclay WR, Elena Stylianou, Helen McShane, Matthew J. Paul, Rajko Reljic, Resende Co T, Rodriguez A, Uranga S, Wong EA   +8 more
core   +1 more source

ROTAVIRUS VACCINATION

Medical Council, 2016
Rotavirus (RV) infection (RVI) which causes acute gastroenteritis (RVGE) is among the most common infectious diseases in children in both developing and developed countries. Before the name RV was invented, the disease was designated as “toxic dyspepsia”, “our cholera” - “cholera nostra”.
openaire   +3 more sources

Comparative evaluation of the potential impact of rotavirus versus hpv vaccination in GAVI-eligible countries: A preliminary analysis focused on the relative disease burden [PDF]

, 2011
Background Immunization policymakers at global and local levels need to establish priorities among new vaccines competing for limited resources.
Sun-Young Kim, Steven Sweet, Joshua Chang, Sue J Goldie, Kim, Sun-Young   +4 more
core   +1 more source

The rise of companies from emerging markets in global health governance: opportunities and challenges [PDF]

, 2014
The article analyses the involvement of pharmaceutical companies from emerging markets in global health governance. It finds that they play a central role as low-cost suppliers of medicines and vaccines and, increasingly, new technologies.
ANNE ROEMER-MAHLER, Brooks, Brown, Buse, Chaudhuri, Clarke, Cooper Ramo, Drezner, Elbe, Fleury, Gold, Knight, Levy, Meyer, Petryna, Ramamurti, Roemer-Mahler, Schoofs, Wells, Whyte, Williams, Williamson, Youde, Zimmerman   +23 more
core   +1 more source

A Novel Rotavirus Reverse Genetics Platform Supports Flexible Insertion of Exogenous Genes and Enables Rapid Development of a High-Throughput Neutralization Assay

Viruses, 2023
Despite the success of rotavirus vaccines, rotaviruses remain one of the leading causes of diarrheal diseases, resulting in significant childhood morbidity and mortality, especially in low- and middle-income countries. The reverse genetics system enables
Jiajie Wei, Scott Radcliffe, Amanda Pirrone, Meiqing Lu, Yuan Li, Jason Cassaday, William Newhard, Gwendolyn J. Heidecker, William A. Rose II, Xi He, Daniel Freed, Michael Citron, Amy Espeseth, Dai Wang   +13 more
doaj   +1 more source

Factors affecting the vaccination choices of pregnant women for their children. A systematic review of the literature [PDF]

, 2020
In recent years, an increase in vaccine hesitancy has led to a decrease in vaccination coverage in several countries. We conducted a systematic review of studies that assessed knowledge of and attitudes toward pediatric vaccinations, and the vaccination ...
Baccolini, V., De Vito, C., Marzuillo, C., Massimi, A., Nardi, A., Pitini, E., Rosso, A., Villari, P.   +7 more
core   +2 more sources

Diversity Patterns of Domestic Herbivore Viruses in China Reveal Transmission Dynamics with Disease Management Implications

Advanced Science, EarlyView.
This study performs pan‐viromic profiling of 14,529 samples from 5,710 domestic herbivores across five Chinese provinces, establishing the DhCN‐Virome (1,085,360 viral metagenomes). It reveals species/sample‐specific viromic signatures and cross‐species transmission dynamics, aiding unified disease control.
Yue Sun, Yong Li, Bagen Temur, Yuanqing Lin, Yuhang Liu, Le Yi, Zheng Sun, Gang Zhang, Jun Li, Yu Guo, Linchuan Li, Jinshan Cai, Wenliang Tian, Gen Meng, Lingling Jiang, Min Fang, Fuying Ding, Xuezhang Zhou, Changchun Tu, Biao He   +19 more
wiley   +1 more source

Evaluating the potential economic and health impact of rotavirus vaccination in 63 middle-income countries not eligible for Gavi funding: a modelling study

The Lancet Global Health, 2021
Summary: Background: Middle-income countries (MICs) that are not eligible for funding from Gavi, the Vaccine Alliance, have been slow to adopt rotavirus vaccines.
Frédéric Debellut, MSc, Andrew Clark, PhD, Clint Pecenka, PhD, Jacqueline Tate, PhD, Ranju Baral, PhD, Colin Sanderson, ProfPhD, Umesh Parashar, MD, Deborah Atherly, PhD   +7 more
doaj   +1 more source