Results 41 to 50 of about 722 (194)

Synergistic Antitumor Effect of Amorphigenin Combined with Cisplatin in Human Lung Adenocarcinoma A549/DDP Cells

open access: yesChinese Journal of Lung Cancer, 2016
Background and objective Amorphigenin, a rotenoid compouns, from seeds of Amorpha fruticosa, has been shown to possess anti-proliferation activities in several cancer cells.
Hongzhen ZHONG   +7 more
doaj   +1 more source

Caeruleanone A, a rotenoid with a new arrangement of the D-ring from the fruits of Millettia caerulea

open access: yes, 2014
Caeruleanone A (1), a novel rotenoid with an unprecedented arrangement of the D-ring, was isolated with another two new analogues, caeruleanones B (2) and C (3), together with 11 known rotenoids from the fruits of Millettia caerulea.
Acuña, Ulyana Muñoz,   +9 more
core   +1 more source

Biopesticides from Amorpha fruticosa, Can We Turn the Dice and Use This Aggressive Invasive Arboreal as Economically Prospective Source of Compounds Capable to Control Pests on Crops? [PDF]

open access: yesResearch Journal of Pharmacognosy
The global decline of pollinators and particularly the decline of bumblebees is a well-proven fact. Their conservation is a leading task in searching for new biopesticides. Amorpha fruticosa L. (Fabaceae) is alien invasive plant in all parts of the world.
Ekaterina Kozuharova   +7 more
doaj   +1 more source

The oxidative ring expansion of spiro-annulated chroman-4-ones: Syntheses of the rotenoid core and related benzoxanthones

open access: yes, 1998
Syntheses of dehydrorotenoid and benzoxanthone units from 2′-hydroxyacetophenone are described which feature a novel migration of spiro-substituted chroman-4-ones during their oxidative ring expansion.
Christopher D. Gabbutt   +7 more
core   +1 more source

Homoisoflavonoids—From Natural Specificity and Biosynthesis to Precision Health‐Promoting Mechanisms

open access: yesFood Frontiers, Volume 7, Issue 3, May 2026.
Homoisoflavonoids are rare flavonoids with a unique bi‐aromatic oxygen‐heterocyclic structure. This review synthesizes their structure–activity relationships in anti‐inflammatory, hypoglycemic, and anticancer contexts. By highlighting their specific natural distribution and outlining biosynthetic pathways, it provides a conceptual framework and ...
Jing Zhang   +4 more
wiley   +1 more source

Spasmolytic Effects of Nonprenylated Rotenoid Constituents of Boerhaavia diffusa Roots

open access: yes, 2006
Boerhaavia diffusa is an Ayurvedic remedy used traditionally for the treatment of a number of diseases, including those affecting the gastrointestinal tract. In the current investigation, a methanol extract obtained from roots of B.
BORRELLI, FRANCESCA   +5 more
core   +1 more source

The Natural Rotenoid Deguelin Ameliorates Diabetic Neuropathy by Decreasing Oxidative Stress and Plasma Glucose Levels in Rats via the Nrf2 Signalling Pathway

open access: yesCellular Physiology and Biochemistry, 2018
Background/Aims: Deguelin is a natural rotenoid that shows anti-inflammatory and antimicrobial activities. Rotenoids prevent oxidative damage and potentiate natural antioxidant activity in diabetic conditions, suggesting utility in treating diabetes and ...
Ji Chen   +5 more
doaj   +1 more source

Micro and Nanoencapsulation of Omega‐3 Fatty Acids: Functional Applications and Future Perspectives in Food Systems

open access: yesFood Safety and Health, Volume 4, Issue 2, Page 280-298, April 2026.
Whey protein‐based microencapsulation for omega‐3 PUFA delivery in food systems. Objective: Enhance oxidative stability & bioavailability of omega‐3 PUFAs using whey protein as an encapsulating agent. Current methods: Spray drying & coacervation—effective but limited by heat sensitivity and encapsulation efficiency. Emerging technologies: Electrospray &
Jihan M. Kassem   +9 more
wiley   +1 more source

The State of Knowledge of the Primary and Secondary Metabolites of the Iris Genus

open access: yesChemistry &Biodiversity, Volume 23, Issue 1, January 2026.
The genus Iris L. (Iridaceae) comprises over 320 species, primarily found in the northern hemisphere. Iris species are important in horticulture, folklore and medicine, and contain a variety of primary and secondary metabolites with significant biological activity.
Olha Mykhailenko   +3 more
wiley   +1 more source

Deguelin Inhibits the Migration and Invasion of U-2 OS Human Osteosarcoma Cells via the Inhibition of Matrix Metalloproteinase-2/-9 in Vitro

open access: yesMolecules, 2014
Osteosarcoma is the most common malignant primary bone tumor in children and young adults and lung metastasis is the main cause of death in those patients. Deguelin, a naturally occurring rotenoid, is known to be an Akt inhibitor and to exhibit cytotoxic
Hung-Sheng Shang   +10 more
doaj   +1 more source

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