Results 71 to 80 of about 722 (194)

Synthesis of deguelin–biotin conjugates and investigation into deguelin’s interactions

open access: yes, 2012
Deguelin, a rotenoid, has emerged as an attractive pharmacophore for chemoprevention showing in vivo activity in several xenografts. Recently, several lines of evidence have suggested its mode of action may involve inhibition of HSP90, however binding in
Katarzyna Gorska   +9 more
core   +1 more source

Novel Bioactive Cubé Insecticide Constituents:  Isolation and Preparation of 13-homo-13-Oxa-6a,12a-dehydrorotenoids

open access: yes, 2016
Two novel rotenoid-like compounds isolated from cubé resin, used as an insecticide and piscicide, have an unprecedented skeleton consisting of a 1,5-benzodioxepin (A and B rings) and a chromone (C and D rings).
John E. Casida (198031)   +1 more
core   +1 more source

Nonprenylated Rotenoids, a New Class of Potent Breast Cancer Resistance Protein Inhibitors

open access: yes, 2016
Two rotenoids isolated from Boerhaavia diffusa (Nyctaginaceae), boeravinones G (1) and H (2), have been found to potently inhibit the drug efflux activity of breast cancer resistance protein (BCRP/ABCG2), a multidrug transporter responsible for cancer ...
Sira Macalou (2495500)   +6 more
core   +1 more source

STUDIES TOWARD TOTAL SYNTHESIS OF (-)-DEGUELIN

open access: yes, 2013
Deguelin, as a rotenoid, has emerged as an attractive pharmacophore for chemprevention due to its effectiveness for both in vitro and in vivo models.
Li, Bao
core  

Rotenoids from Boerhaavia diffusa as Potential Anti-inflammatory Agents

open access: yes, 2016
Five new (2, 3, 5, 7, and 9) and four known rotenoids (1, 4, 6, and 8) were isolated from a methanol extract of Boerhaavia diffusa roots. The structures of the new rotenoids were elucidated by spectroscopic data interpretation. The 70% ethanol extract, a
Amit Srivastava (23227)   +5 more
core   +1 more source

Antiplasmodial and larvicidal flavonoids from Derris trifoliate

open access: yesBulletin of the Chemical Society of Ethiopia, 2009
From the dichloromethane-methanol (1:1) extract of the seed pods of Derris trifoliata, a new flavanone derivative (S)-lupinifolin 4´-methyl ether was isolated. In addition, the known flavonoids lupinifolin and rotenone were identified.
Abiy Yenesew   +9 more
doaj  

Expedient syntheses of the rotenoid and thiorotenoid systems

open access: yes, 1994
A simple four-step synthesis of a 6,6-disubstituted 6a,12a-dihydro-6H,12H-[1]benzopyrano[3,4,-b]-[1]benzopyran-12-one 6 from a chroman-4-one 3 is described.
Gabbutt, Christopher D.   +2 more
core   +1 more source

Deguelin induces apoptosis in colorectal cancer cells by activating the p38 MAPK pathway

open access: yesCancer Management and Research, 2018
Liubo Chen,1,2,* Kai Jiang,1,2,* Haiyan Chen,1,3,* Yang Tang,1,2 Xinyi Zhou,1,2 Yinuo Tan,1,4 Ying Yuan,1,4 Qian Xiao,1,2 Kefeng Ding1,2 1Cancer Institute (Key Laboratory of Cancer Prevention and Intervention, China National Ministry of Education, Key ...
Chen L   +8 more
doaj  

New Class of Tyrosinase Inhibitors, Rotenoids, from Amorpha fruticosa. [PDF]

open access: yesACS Omega, 2023
Moon SW   +5 more
europepmc   +1 more source

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