Results 71 to 80 of about 722 (194)
Synthesis of deguelin–biotin conjugates and investigation into deguelin’s interactions
Deguelin, a rotenoid, has emerged as an attractive pharmacophore for chemoprevention showing in vivo activity in several xenografts. Recently, several lines of evidence have suggested its mode of action may involve inhibition of HSP90, however binding in
Katarzyna Gorska +9 more
core +1 more source
Two novel rotenoid-like compounds isolated from cubé resin, used as an insecticide and piscicide, have an unprecedented skeleton consisting of a 1,5-benzodioxepin (A and B rings) and a chromone (C and D rings).
John E. Casida (198031) +1 more
core +1 more source
Nonprenylated Rotenoids, a New Class of Potent Breast Cancer Resistance Protein Inhibitors
Two rotenoids isolated from Boerhaavia diffusa (Nyctaginaceae), boeravinones G (1) and H (2), have been found to potently inhibit the drug efflux activity of breast cancer resistance protein (BCRP/ABCG2), a multidrug transporter responsible for cancer ...
Sira Macalou (2495500) +6 more
core +1 more source
STUDIES TOWARD TOTAL SYNTHESIS OF (-)-DEGUELIN
Deguelin, as a rotenoid, has emerged as an attractive pharmacophore for chemprevention due to its effectiveness for both in vitro and in vivo models.
Li, Bao
core
Rotenoids from Boerhaavia diffusa as Potential Anti-inflammatory Agents
Five new (2, 3, 5, 7, and 9) and four known rotenoids (1, 4, 6, and 8) were isolated from a methanol extract of Boerhaavia diffusa roots. The structures of the new rotenoids were elucidated by spectroscopic data interpretation. The 70% ethanol extract, a
Amit Srivastava (23227) +5 more
core +1 more source
Antiplasmodial and larvicidal flavonoids from Derris trifoliate
From the dichloromethane-methanol (1:1) extract of the seed pods of Derris trifoliata, a new flavanone derivative (S)-lupinifolin 4´-methyl ether was isolated. In addition, the known flavonoids lupinifolin and rotenone were identified.
Abiy Yenesew +9 more
doaj
Expedient syntheses of the rotenoid and thiorotenoid systems
A simple four-step synthesis of a 6,6-disubstituted 6a,12a-dihydro-6H,12H-[1]benzopyrano[3,4,-b]-[1]benzopyran-12-one 6 from a chroman-4-one 3 is described.
Gabbutt, Christopher D. +2 more
core +1 more source
Deguelin induces apoptosis in colorectal cancer cells by activating the p38 MAPK pathway
Liubo Chen,1,2,* Kai Jiang,1,2,* Haiyan Chen,1,3,* Yang Tang,1,2 Xinyi Zhou,1,2 Yinuo Tan,1,4 Ying Yuan,1,4 Qian Xiao,1,2 Kefeng Ding1,2 1Cancer Institute (Key Laboratory of Cancer Prevention and Intervention, China National Ministry of Education, Key ...
Chen L +8 more
doaj
New Class of Tyrosinase Inhibitors, Rotenoids, from Amorpha fruticosa. [PDF]
Moon SW +5 more
europepmc +1 more source
Variation in Rotenone and Deguelin Contents among Strains across Four Tephrosia Species and Their Activities against Aphids and Whiteflies. [PDF]
Zhang P +5 more
europepmc +1 more source

