Results 231 to 240 of about 64,618 (285)

CRISPR screens in iPSC-derived neurons reveal principles of tau proteostasis. [PDF]

Cell
Samelson AJ, Ariqat N, McKetney J, Rohanitazangi G, Parra Bravo C, Bose RS, Travaglini KJ, Lam VL, Goodness D, Ta T, Dixon G, Marzette E, Jin J, Tian R, Tse E, Abskharon R, Pan HS, Carroll EC, Lawrence RE, Gestwicki JE, Rexach JE, Eisenberg DS, Kanaan NM, Southworth DR, Gross JD, Gan L, Swaney DL, Kampmann M.   +27 more
europepmc   +1 more source

Downregulation of microRNA‐494 drives mitochondrial biogenesis and function in trained muscle

Experimental Physiology, Volume 111, Issue 3, Page 1093-1108, 1 March 2026.
Abstract MicroRNAs (miRNAs) are key regulators of cellular processes, including mitochondrial function and energy metabolism. This study explores the regulation of miR‐494 in skeletal muscle and circulation, investigating its response to exercise training and an acute exercise bout, its association with metabolic disorders, and the effects of ...
Natália Pálešová, Klára Gabrišová, Jana Babulicová, Patrik Krumpolec, Zuzana Kovaničová, Tímea Kurdiová, Salvatore Modica, Christian Wolfrum, Jozef Ukropec, Barbara Ukropcová, Miroslav Baláž   +10 more
wiley   +1 more source

Tubulin hyperacetylation drives HMGB1 nuclear exit via the ROS-PARP1 axis, leading to rotenone-induced G2/M arrest. [PDF]

J Biol Chem
Dutta S, Chakraborty S, Ghosh A, Halder P, Majumder S, Paul R, Nath S, Mukherjee P.   +7 more
europepmc   +1 more source

Early sensorimotor restriction in rats induces age‐dependent mitochondrial alterations in skeletal muscles and brain structures

The Journal of Physiology, Volume 604, Issue 6, Page 2512-2524, 15 March 2026.
Abstract figure legend This study aimed to determine whether early sensorimotor restriction (SMR) alters mitochondrial enzyme activities in rat muscles and brain structures. SMR was induced via immobilizing the hind limbs of pups for 16 h per day during the dark phase from birth to postnatal day (PND) 28.
Mélanie Van Gaever, Olivier Dupuy, Erwan Dupont, Marie‐Hélène Canu, Frederic Daussin   +4 more
wiley   +1 more source

Mitochondrial Metabolic Reprogramming of Cortical Neurons by Prenatal Exposure to Corticosterone: A Shift from ATP Synthesis to Membrane Potential Maintenance. [PDF]

Exp Neurobiol
Amarsanaa K, Badarch M, Kim HY, Kwon OB, Baek EB, Ko EA, Jung SC.   +6 more
europepmc   +1 more source

Role of Septin7 in mitochondrial dynamics and oxidative metabolism in C2C12 skeletal muscle cells

The Journal of Physiology, Volume 604, Issue 5, Page 1971-1994, 1 March 2026.
Abstract figure legend Knockdown of Septin7 alters the expression of markers responsible for mitochondrial dynamics. Members of the electron transport chain are also affected by diminished Septin7 level resulting in functional changes of mitochondrial respiration. Abstract Mitochondria are dynamic organelles that undergo fusion and fission.
Andrea Telek, Ivett Gabriella Szabó, Anikó Keller‐Pintér, Mónika Gönczi, Eliza Guti, László Szabó, Brigitta Tillmann, Zoltán Márton Kohler, László Juhász, Péter Bai, Szilárd Póliska, Zsuzsanna Gaál, László Csernoch, János Fodor   +13 more
wiley   +1 more source

Multi-omics analysis reveals metabolic diversity underlying endothelial cell functions. [PDF]

Life Sci Alliance
Durot S, Doubleday PF, Schulla L, Sabine A, Petrova TV, Zamboni N.   +5 more
europepmc   +1 more source

Concentration-dependent effects of bacterial melanin on new superoxide-producing associates in rat tissues: a rotenone neurotoxic model of parkinson's disease. [PDF]

BMC Pharmacol Toxicol
Danielyan M, Karapetyan K, Simonyan R, Simonyan G, Babayan M, Poghosyan M, Yekmalyan H, Simonyan M, Simonyan K, Nebogova K.   +9 more
europepmc   +1 more source

Infection and herbicide exposure implicate c-Abl kinase in α-Synuclein Ser129 phosphorylation. [PDF]

Cell Commun Signal
Ehsani M, Sun Z, Quevedo-Olmos A, Rösler G, Rasa M, Remes AK, Hedemann N, Müller OJ, Erttmann SF, Holthaus D, Meyer TF.   +10 more
europepmc   +1 more source

Correction: Thomas Broome, S.; Castorina, A. Systemic Rotenone Administration Causes Extra-Nigral Alterations in C57BL/6 Mice. <i>Biomedicines</i> 2022, <i>10</i>, 3174. [PDF]

Biomedicines
Thomas Broome S, Castorina A.
europepmc   +1 more source