Results 81 to 90 of about 3,523,664 (305)

Sleep Alters the Velocity of Physiological Brain Pulsations in Humans

Advanced Science, EarlyView.
Sleep alters I/CSF oscillatory flow, driven by increased respiratory (29%) and vasomotor pulsation (21%) velocities, while cardiovascular pulsations decreased by (22%). Velocity is quantified using optical flow analysis of MREG data. Spectral power increases alongside these pulsations (spatial correlation, r = 0.35 and r = 0.39, respectively ...
Ahmed Elabasy, Heta Helakari, Tommi Väyrynen, Zalán Rajna, Niko Huotari, Lauri Raitamaa, Ville Isokoski, Matti Järvelä, Mika Kaakinen, Johanna Piispala, Mika Kallio, Vesa Korhonen, Tapio Seppänen, Vesa Kiviniemi   +13 more
wiley   +1 more source

Study on the reverse design of screw rotor profiles based on a B-spline curve

Advances in Mechanical Engineering, 2019
The female/male screw rotor profile design for a twin screw compressor poses challenges such as frequent parameter modification and a difficult-to-build performance test platform, which affect the efficiency of a rotor profile design.
Shu Cao, Xueming He, Rong Zhang, Junfeng Xiao, Guojiang Shi   +4 more
doaj   +1 more source

Rotor dynamic analysis of a tidal turbine considering fluid–structure interaction under shear flow and waves

International Journal of Naval Architecture and Ocean Engineering, 2019
A rotor dynamic analysis is mandatory for stability and design optimization of submerged propellers and turbines. An accurate simulation requires a proper consideration of fluid-induced reaction forces.
Andre Laß, Matti Schilling, Jitendra Kumar, Frank-Hendrik Wurm   +3 more
doaj   +1 more source

Tailoring Vascular‐Immune Homeostasis via Manganese‐DNA Complex‐Armed Immunogenic Extracellular Vesicles for Pancreatic Cancer Immunotherapy

Advanced Science, EarlyView.
This study demonstrates that Mn2⁺–tumor DNA complexes encapsulated in dendritic cell (DC)– derived immunogenic extracellular vesicles (EVDC@Mn‐DNA) act as a DC‐specific cGAS– STING activator. EVDC@Mn‐DNA treatment enhances intratumoral DC activation, improves tumor vascular function, promotes CD8⁺ T cell activity, and suppresses pancreatic tumor growth,
Xue Jiang, Lihuan Shang, Xiaochun Chen, Xiangzhan Kong, Xiaojuan Wang, Linjia Jiang, Huiying Zhao, Yafeng Zhu, Cheng Huang, Shiyi Deng, Rui Zhang, Minghui Wang, Haoming Lin, Ping‐Pui Wong   +13 more
wiley   +1 more source

NONLIEAR DYNAMIC BEHAVIORS ANALYSIS OF COMPLEX ROTOR-BEARING SYSTEM

Jixie qiangdu, 2015
Aiming at overcoming the deficiency of available methods for revaling the nonlinear dynamic behaviors of complex rotor-bearing system,a fluid-structure method which combined rotor dynamics with computational fluid dynamics based on dynamic mesh is ...
LIN LuSheng, LIU GuiPing, CHEN Yuan
doaj  

Multiphysics Optimization of a High-Speed Permanent Magnet Motor Based on Subspace and Sequential Strategy

Applied Sciences
In the optimization of high-speed permanent magnet motors (HSPMMs), electromagnetic characteristics, rotor stress, rotor dynamics, and temperature characteristics must all be considered simultaneously, and there are numerous optimization parameters for ...
Honglin Yan, Guanghui Du, Wentao Gao, Yanhong Chen, Cunlong Cui, Kai Xu   +5 more
doaj   +1 more source

Extracellular Vesicles of Streptococcus anginosus Mediate Gastritis via Epithelial Barrier Disruption and Macrophage‐driven Inflammation

Advanced Science, EarlyView.
Streptococcus anginosus extracellular vesicles (SA‐EVs) accumulate in gastric tissue, disrupt epithelial tight junctions, and induce gastritis characterized by neutrophil infiltration and elevated cytokines (TNF‐α, IL‐6, IL‐17A). Proteomics identifies TMPC and FBP62 as key SA‐EVs virulence factors; their genetic deletion attenuates inflammation ...
Ying Gong, Lina Duan, Jie Xiao, Yulu Deng, Hongxia Wang, Yajie Zhang, Xiumei Hu, Haifang Wang, Taixue An, Xin Li, Yurong Qiu, Lei Zheng, Haixia Li   +12 more
wiley   +1 more source

Numerical Investigation Using Harmonic and Transient Analysis To Rotor Dynamics

Journal of Engineering, 2016
The rotor dynamics generally deals with vibration of rotating structures. For designing rotors of a high speeds, basically its important to take into account the rotor dynamics characteristics.
Adnan Naji Jameel Al Tamim, Jassim Farij Thijeel Al Draji   +1 more
doaj   +2 more sources

Endocytic Control of Cell‐Autonomous and Non‐Cell‐Autonomous Functions of p53

Advanced Science, EarlyView.
NUMB Ex3‐containing isoforms localize to the plasma membrane, where they recruit p53 through SNX9 and direct it to multivesicular bodies and exosomes. Exported p53 is taken up by neighboring cells and activates nuclear programs, revealing an intercellular, exosome‐based pathway that might help establish a tumor‐suppressive microenvironment.
Roberta Cacciatore, Andrea Basile, Stefano Freddi, Irene Schiano Lomoriello, Carlo Ribelle Zucca, Giuseppe Ciossani, Luigi Scietti, Alessandro Cuomo, Simona Ronzoni, Simone Pelicci, Mario Faretta, Elena Zaccheroni, Giuliana Pelicci, Vittoria Matafora, Angela Bachi, Rosalind Helen Gunby, Salvatore Pece, Sara Sigismund, Letizia Lanzetti, Ivan Nicola Colaluca, Pier Paolo Di Fiore   +20 more
wiley   +1 more source

Logic‐Gated HSV‐TK/GCV Suicide Gene Circuit for Triple‐Negative Breast Cancer

Advanced Science, EarlyView.
The BRAS comprises two modular genetic components driven by distinct tumor‐specific promoters and a failsafe layer with the NOT gate. This multi‐input logic gate circuit enables precise, specific expression of HSV‐TK in breast cancer cells with hardly expression in normal cell and effectively inhibits tumor growth in a triple‐negative breast cancer ...
Shasha Tang, Yuan Fang, Lingli Jin, Dongyang Liu, Yicheng Liu, Ruijia Zheng, Liyun Yong, Xin Wu, Longliang Qiao, Meiyan Wang, Fengfeng Cai   +10 more
wiley   +1 more source