Results 41 to 50 of about 1,267,417 (323)

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

Some characteristics of matroids through rough sets [PDF]

, 2012
At present, practical application and theoretical discussion of rough sets are two hot problems in computer science. The core concepts of rough set theory are upper and lower approximation operators based on equivalence relations. Matroid, as a branch of
Su, Lirun, Zhu, William
core  

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Roughness in Membership Continuous Function

مجلة المختار للعلوم, 2021
In this paper, we introduce the new definition of rough membership function using continuous function and we discuss several concepts and properties of rough continuous set value functions as new results on rough continuous function and membership ...
Faraj.A. Abdunani, Ahmed.A. Shletiet
doaj   +1 more source

Class Association Rules Mining based Rough Set Method [PDF]

, 2015
This paper investigates the mining of class association rules with rough set approach. In data mining, an association occurs between two set of elements when one element set happen together with another. A class association rule set (CARs) is a subset of
Slimani, Thabet
core  

Production of antibacterial compounds by a Steely hybrid polyketide synthase in Dictyostelium

FEBS Open Bio, EarlyView.
By selecting appropriate production species under optimised culture conditions, new chlorinated dibenzofuran compounds, which previously could not be analysed in sufficient quantities, were identified from cellular slime mould fruiting bodies. The strong antibacterial activity exhibited by these compounds suggests a link to the ecological function of ...
Tomoaki R. Yamashita, Toyonobu Usuki, Robert R. Kay, Tamao Saito   +3 more
wiley   +1 more source

Thrombolytic proteins profiling: High‐throughput activity, selectivity, and resistance assays

FEBS Open Bio, EarlyView.
We present optimized biochemical protocols for evaluating thrombolytic proteins, enabling rapid and robust screening of enzymatic activity, inhibition resistance, and fibrin affinity, stimulation, and selectivity. The outcome translates to key clinical indicators such as biological half‐life and bleeding risk. These assays streamline the development of
Martin Toul, Alan Strunga, Jiri Damborsky, Zbynek Prokop   +3 more
wiley   +1 more source

Granular Space Reduction to a β Multigranulation Fuzzy Rough Set

Abstract and Applied Analysis, 2014
Multigranulation rough set is an extension of classical rough set, and optimistic multigranulation and pessimistic multigranulation are two special cases of it. β multigranulation rough set is a more generalized multigranulation rough set. In this paper,
Junyi Zhou, Shaohui Ma, Jianzhen Li
doaj   +1 more source

Overview of molecular signatures of senescence and associated resources: pros and cons

FEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas, Sylvia Vagena, Pavlos Pantelis, Giorgos Theocharous, Russel Petty, Konstantinos Evangelou, Vassilis G. Gorgoulis   +6 more
wiley   +1 more source

Two kinds of average approximation accuracy

CAAI Transactions on Intelligence Technology
Rough set theory places great importance on approximation accuracy, which is used to gauge how well a rough set model describes a target concept. However, traditional approximation accuracy has limitations since it varies with changes in the target ...
Qingzhao Kong, Wanting Wang, Dongxiao Zhang, Wenbin Zhang   +3 more
doaj   +1 more source