Results 121 to 130 of about 5,733 (291)

Rocket‐Inspired Sequentially Targeted Nanotherapeutics for Mitochondrial Regulation and Inflammatory Reprogramming in Ischemic Stroke

Advanced Science, EarlyView.
A novel neutrophil‐hitchhiking, rocket‐inspired nanoplatform is developed to cross the blood‐brain barrier for sequential, spatiotemporal drug delivery. By responsive surface transformation in the ischemic penumbra, it precisely targets mitochondria to suppress Drp1‐mediated fission.
He Bai, Zihao Yong, Yang Li, Qingmin Chen, Yong Liu, Xiaomeng Guo, Fukai Li, Shicheng Tang, Zhuo Yang, Yufei Zhang, Ruwei Jie, Xiaohong Lv, Huacheng Wang, Chunming Huang, Liwei Xie, Jianqi Xiao, Qingchun Mu, Longguang Tang   +17 more
wiley   +1 more source

Beyond Traditional Phenolics: Disulfide Bonds for Performance Enhancement of Aerospace Ablation‐Resistant Materials from Processing to Recycling

Advanced Science, EarlyView.
The dynamic disulfide bonds facilitated the development of high‐performance aerospace ablation‐resistant materials. At moderate temperature, the dissociation and recombination of disulfide bonds ensured excellent processability, mechanical properties, and recycling ability of phenolic resin; at high temperature, cleavage of disulfide bonds produced ...
Yu Li, Boyuan Hu, Xiaolong Xing, Huan Yang, Ziqi Zhang, Cheng Bian, Ruixue Bai, Ling Yue, Chengshuang Zhang, Xinli Jing   +9 more
wiley   +1 more source

Roundabouts for safer roads

, 2009
This paper describes guidelines and research results about the design of roundabouts and their effects on traffic safety. After an introduction, the principal geometric elements of a roundabout are discussed in relation to traffic safety.
De Winne, Etienne
core   +1 more source

A Monolithic Janus Hydrogel Pressure Sensor for Wearable Motion and Physiological Monitoring

Advanced Science, EarlyView.
This work reports a monolithic Janus hydrogel pressure sensor featuring integrated conductive PEDOT and insulating PEGDA layers. The fabricated device achieves a rapid response time, a wide operating range, and good cyclic durability. The sensor demonstrates robust performance in tracking dynamic human joint motions, offering a scalable strategy for ...
Syed Atif Ali, Zeeshan Alam Ansari, Reynaldo Carlos Kuizon Montalbo, Hailemichael Ayalew, Yu‐Sheng Hsiao, Chih‐Wei Chu, Hsiao‐hua Yu, Hsiung‐Lin Tu   +7 more
wiley   +1 more source

Accidents at 4-Arm roundabouts

, 1984
Gives the findings of a study of personal injury accidents at a sample of 84 four-arm roundabouts on main roads in the UK. The study included small roundabouts and roundabouts of conventional design, in both 30-40 and 50-70 mile/h speed limit ...
Hall, R.D., Maycock, G.
core   +1 more source

AARS1‐Mediated RUNX3 K193 Lactylation Enhances the Activation and Cytotoxicity of CD8+T Cells in Smoking‐Related Emphysema

Advanced Science, EarlyView.
Exposure to CS causes an elevation of AARS1 levels, which increases the levels of RUNX3 lactylation at the K193 site and increases protein levels of RUNX3 through inhibition of autolysosomal degradation. Elevated RUNX3 levels promote CD8+T cell activation and augment their cytotoxicity, which induces alveolar epithelial cell death and facilitates the ...
Ying Zhu, Jiaheng Lin, Yifan Li, Qiaoqiao Zhou, Min Yu, Cheng Cheng, Kang Chang, Dang Lin, Tao Bian, Yan Wu, Lu Lu, Haibo Xia, Qizhan Liu   +12 more
wiley   +1 more source

Modern Roundabouts for Oregon

00924088404592981998PDFTech ReportOR-RD-98-17RoundaboutsHighway designIntersectionsState of the practiceRoundaboutsdesignintersectionsUnited StatesOregonOregon. Dept. of TransportationTaekratok, ThaweesakOregon. Dept. of Transportation.

core  

Structural Control Over Bicontinuous Emulsions from Solvent‐Transfer Induced Phase Separation Through Nanoparticle Loading

Advanced Science, EarlyView.
The nanoparticle loading enables effective control over the liquid domain size in bicontinuous interfacially jammed emulsion gels (bijels) produced through solvent‐transfer induced phase separation (STrIPS). The relationship between the nanoparticle loading and domain size profiles in STrIPS bijels is resolved through confocal microscopy and explained ...
Jesse M. Steenhoff, Martin F. Haase
wiley   +1 more source

Enhancing Safety of Navigation: Redesigning Precautionary Areas into Roundabouts in Marine Traffic Separation Schemes

Applied Sciences
Roundabouts are widely used in road transport to improve traffic flow and reduce congestion by enabling continuous movement in a circular pattern, minimizing stops, enhancing safety, and reducing delays compared to that of signaled intersections. However,
Joe Ronald Kurniawan Bokau, Gokhan Camliyurt, Antoni Arif Priadi, Youngsoo Park, Daewon Kim   +4 more
doaj   +1 more source

Roundabouts [PDF]

Nature, 2011
openaire   +1 more source