Results 121 to 130 of about 1,483 (262)

Radiation‐Induced Tumor‐Intrinsic LTβR N‐Glycosylation Suppresses Pyroptosis Through TRIM28‐Mediated PCBP2 SUMOylation to Promote Gastric Cancer Radioresistance

open access: yesAdvanced Science, EarlyView.
Radiotherapy triggers LTβR N‐glycosylation, enhancing its overall protein stability and nuclear retention. This accumulation drives TRIM28‐mediated PCBP2 SUMOylation, suppressing pyroptosis and conferring gastric cancer radioresistance. Therapeutically, a targeted nanoplatform (cRGD‐Lipo@EMD) effectively disrupts this regulatory axis, offering a highly
Weijie Zang   +8 more
wiley   +1 more source

Tandem Duplication‐Driven Neofunctionalization of UDP‐Glycosyltransferases Shapes the Diversification of Triterpenoid Saponins in the Cucurbitaceae

open access: yesAdvanced Science, EarlyView.
We present a chromosome‐level genome assembly of Siraitia grosvenorii and, through comparative genomics, uncover a conserved UGT73 tandem array driving triterpenoid saponin diversification in Cucurbitaceae. Crystalized SgUGT73AM30 further reveals the regioselectivity mechanism underlying its catalytic activity.
Guangyi Wang   +13 more
wiley   +1 more source

Round a Roundabout

open access: yes, 2018
Vanaf 21 september 2018 is in CCHA drie maanden lang het retrospectief Patrick Ceyssens. Van kijken naar beelddenken te zien (later tijdens het IMPACT Festival ook met Round a roundabout #2). Er verschijnt een bijbehorend boek waarmee met behulp van een app allerlei beelden op de smartphone en de iPad zijn op te roepen.
GIELIS, Sofie   +2 more
openaire   +1 more source

ZrO2 Aerogel‐Supported Pd Nanoparticles for Photothermal CO2 Reduction

open access: yesAdvanced Science, EarlyView.
Nanoparticle‐based aerogels are promising catalysts for photothermal reactions due to optical transparency, high surface area, and low thermal conductivity. Here, we present deposition of Pd nanoparticles on ZrO2 aerogel granules by a wet‐impregnation approach.
David Kiwic   +3 more
wiley   +1 more source

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