Results 41 to 50 of about 5,725 (291)

Case studies of landscape and environmental impact evaluation of roundabouts [PDF]

open access: yes, 2011
This paper is a follow-up to a previous one that presented a new method for evaluating the landscape and environmental impact of roundabouts borrowed from building technology and based on the needs, requirements and performance expected from an object ...
MUSSONE, LORENZO   +3 more
core  

Bridging the gap: a genetically validated avian chorioallantoic membrane platform for investigation of spontaneous circulating tumor cells

open access: yesMolecular Oncology, EarlyView.
We established the avian chorioallantoic membrane (CAM) assay as a scalable in vivo model for studying circulating tumor cells (CTCs). Human gastrointestinal tumors spontaneously released genetically validated CTCs that were detected across multiple platforms, demonstrating that the CAM model provides an accessible tool for investigating early cancer ...
Dennis Roth   +17 more
wiley   +1 more source

Analyses of maximum-speed path definition at single-lane roundabouts

open access: yesJournal of Traffic and Transportation Engineering (English ed. Online), 2018
The process of designing roundabouts is an iterative process through which, in several checks, the design elements of a roundabout get optimized. Existing regulations for roundabouts involve swept path analyses, sight distance analyses and speed analyses
Sanja Šurdonja   +2 more
doaj   +1 more source

Investigating pedestrian injury crashes on modern roundabouts in Addis Ababa, Ethiopia [PDF]

open access: yes, 2015
Pedestrian crashes are one of the major road safety problems in developing countries representing about 40% of total fatal crashes in low income countries.
Haque, Md. Mazharul   +3 more
core   +2 more sources

Treatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease

open access: yesFEBS Open Bio, EarlyView.
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill   +6 more
wiley   +1 more source

Evaluating the effect of γ‐oryzanol on MASLD pathology using a medaka fish model

open access: yesFEBS Open Bio, EarlyView.
This study explores a liver disease called MASLD, which is increasing worldwide and can lead to serious damage. Researchers used medaka fish instead of rodents to test a food compound, γ‐oryzanol. Fish fed this compound had less liver fat and healthier gut bacteria.
Yukako Ito   +7 more
wiley   +1 more source

Identification of Risk Factors Associated with Fatal Intersection Crashes and Assessment of the In-Service Safety Performance of Signalized Intersections and Roundabouts in Abu Dhabi

open access: yesSafety, 2021
Several research studies conducted in North America and Europe have consistently shown that converting signalized intersections into roundabouts leads to safety benefits.
Dina Mustafa Mohammad Awadalla   +1 more
doaj   +1 more source

In silico and in vitro exploration of a tyrosinase for biocatalytic production of catechols

open access: yesFEBS Open Bio, EarlyView.
Tyrosinase from Ralstonia pseudosolanacearum is a promising biocatalyst for producing valuable catechols from monophenol substrates. This tyrosinase is uniquely suited to this due to its high monophenolase : diphenolase ratio. We combined in silico docking and in vivo kinetic characterisation of this tyrosinase with 11 industrially relevant monophenols,
James Britton   +6 more
wiley   +1 more source

Analysis of drivers’ errors at roundabouts in Morocco

open access: yesMATEC Web of Conferences, 2017
Roundabouts have increased in a significant way in recent years in Moroccan cities as they have been seen as a solution to congestion problems and traffic safety issues.
Moutchou Fatiha, Cherkaoui Abdelghani
doaj   +1 more source

A minimal cellulosome‐like system in Cellulosilyticum lentocellum

open access: yesFEBS Open Bio, EarlyView.
Cellulose‐degrading bacteria typically use cellulosomes, large multi‐enzyme complexes on a scaffold protein. In Cellulosilyticum lentocellum, we characterise a far smaller arrangement, a single scaffold bound to one cellulase through a single cohesin‐dockerin interaction.
John Allan   +2 more
wiley   +1 more source

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