Results 51 to 60 of about 197,009 (283)
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Impact of Groove Manufacturing Errors on Aircraft Skin-Friction Reduction
AerospaceThis study systematically investigates the effects of manufacturing errors on the drag reduction performance of micro-grooves fabricated using roll-to-roll hot embossing technology.
Zhaoliang Dou, Yue Du, Fengbin Liu
doaj +1 more source
FEBS Open Bio, EarlyView.CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point +7 more
wiley +1 more source
Addressing limited weight resolution in a fully optical neuromorphic reservoir computing readout
Scientific Reports, 2021 Using optical hardware for neuromorphic computing has become more and more popular recently, due to its efficient high-speed data processing capabilities and low power consumption. However, there are still some remaining obstacles to realizing the vision
Chonghuai Ma +3 more
doaj +1 more source
FEBS Open Bio, EarlyView.ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand +2 more
wiley +1 more source
Lost-minimum post-training parameter quantization method for convolutional neural network
Tongxin xuebao, 2022 To solve the problem that that no dataset is available for model quantization in data-sensitive scenarios, a model quantization method without using data sets was proposed.Firstly, according to the parameters of batch normalized layer and the ...
Fan ZHANG +3 more
doaj +2 more sources
A COMPARISON OF PRE-ROUNDING AND POST-ROUNDING FLOATING POINT DIVIDE ORDERS [PDF]
, 2008 This paper addresses the advantages and disadvantages of pre-rounding vs. post-rounding in a floating-point register. In this day when high speed computers with long registers are the norm, one may think that a rounding scheme is nearly irrelevant ...
Kettler, Paul C.
core
HIV‐1 establishes immediate latency in T cells expressing the viral Nef protein
FEBS Open Bio, EarlyView.Nef is a viral protein often omitted from HIV‐1 reporter viruses. Consequently, its role in viral latency is unclear. We developed three novel dual reporter HIV‐1 derivatives that express Nef and allow for detection of latent and productive infection. Using these reporters, we show that Nef does not affect the establishment of immediate viral latency ...
Cindy Lam, Ivan Sadowski
wiley +1 more source
A Note on the Perturbation of arithmetic expressions
مجلة بغداد للعلوم, 2016 In this paper we present the theoretical foundation of forward error analysis of numerical algorithms under;• Approximations in "built-in" functions.• Rounding errors in arithmetic floating-point operations.• Perturbations of data.The error analysis is ...
Baghdad Science Journal
doaj +1 more source
Development of human monoclonal antibodies against TARM1 by yeast display
FEBS Open Bio, EarlyView.Human monoclonal antibodies against TARM1 are generated by yeast display‐guided selection. These antibodies bind to soluble and cell‐surface forms of TARM1. Also, these antibodies exhibit agonistic activity in the NFAT‐GFP reporter assay, indicating that TARM1 signaling can be functionally modulated by antibodies and suggesting TARM1 as a potential ...
Rikio Yabe +5 more
wiley +1 more source