Results 41 to 50 of about 154,884 (290)

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

open access: yesMolecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix   +13 more
wiley   +1 more source

Fast and accurate evaluation of Wigner 3j, 6j, and 9j symbols using prime factorisation and multi-word integer arithmetic [PDF]

open access: yes, 2015
We present an efficient implementation for the evaluation of Wigner 3j, 6j, and 9j symbols. These represent numerical transformation coefficients that are used in the quantum theory of angular momentum.
Forssén, C., Johansson, H. T.
core   +2 more sources

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

Quasirandom Load Balancing

open access: yes, 2012
We propose a simple distributed algorithm for balancing indivisible tokens on graphs. The algorithm is completely deterministic, though it tries to imitate (and enhance) a random algorithm by keeping the accumulated rounding errors as small as possible.
Lovász L.   +5 more
core   +2 more sources

A Generic Library for Floating-Point Numbers and Its Application to Exact Computing [PDF]

open access: yes, 2001
International audienceIn this paper we present a general library to reason about floating-point numbers within the Coq system. Most of the results of the library are proved for an arbitrary floating-point format and an arbitrary base.
Daumas, Marc   +2 more
core   +3 more sources

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Impact of Groove Manufacturing Errors on Aircraft Skin-Friction Reduction

open access: yesAerospace
This study systematically investigates the effects of manufacturing errors on the drag reduction performance of micro-grooves fabricated using roll-to-roll hot embossing technology.
Zhaoliang Dou, Yue Du, Fengbin Liu
doaj   +1 more source

A non-local method for robustness analysis of floating point programs [PDF]

open access: yesElectronic Proceedings in Theoretical Computer Science, 2012
Robustness is a standard correctness property which intuitively means that if the input to the program changes less than a fixed small amount then the output changes only slightly.
Ivan Gazeau   +2 more
doaj   +1 more source

Another approach to Runge-Kutta methods [PDF]

open access: yes, 2004
The condition equations are derived by the introduction of a system of equivalent differential equations, avoiding the usual formalism with trees and elementary differentials.
Traas, C.R.
core   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

open access: yesFEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point   +7 more
wiley   +1 more source

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