Results 51 to 60 of about 154,884 (290)

From Rounding Error Estimation to Automatic Correction with Automatic Differentiation [PDF]

, 2000
Using automatic differentiation (AD) to estimate the propagation of rounding errors in numerical algorithms is classic. We propose a new application of AD to roundoff analysis providing an automatic correction of the first order effect of the elementary ...
Langlois, Philippe
core   +1 more source

Liapunov Exponents and the Reversibility of Molecular Dynamics Algorithms [PDF]

, 1997
We study the phenomenon of lack of reversibility in molecular dynamics algorithms for the case of Wilson's lattice QCD. We demonstrate that the classical equations of motion that are employed in these algorithms are chaotic in nature.
Andreas Jaster, Benettin, Brower, Chuan Liu, Duane, Edwards, Gottlieb, Horowitz, Horowitz, Horowitz, Jansen, Jansen, Jansen, Karl Jansen, Liapunov, Lichtenberg, Oseledec   +16 more
core   +3 more sources

Differential regulation of ZFAS1 splice variants by endoplasmic reticulum stress in hepatocyte cell lines

FEBS Open Bio, EarlyView.
ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand, Paulina Lau, Ruth McPherson   +2 more
wiley   +1 more source

HIV‐1 establishes immediate latency in T cells expressing the viral Nef protein

FEBS Open Bio, EarlyView.
Nef is a viral protein often omitted from HIV‐1 reporter viruses. Consequently, its role in viral latency is unclear. We developed three novel dual reporter HIV‐1 derivatives that express Nef and allow for detection of latent and productive infection. Using these reporters, we show that Nef does not affect the establishment of immediate viral latency ...
Cindy Lam, Ivan Sadowski
wiley   +1 more source

Number Formats, Error Mitigation, and Scope for 16‐Bit Arithmetics in Weather and Climate Modeling Analyzed With a Shallow Water Model

Journal of Advances in Modeling Earth Systems, 2020
The need for high‐precision calculations with 64‐bit or 32‐bit floating‐point arithmetic for weather and climate models is questioned. Lower‐precision numbers can accelerate simulations and are increasingly supported by modern computing hardware.
M. Klöwer, P. D. Düben, T. N. Palmer
doaj   +1 more source

Performance Prediction and Geometry Optimization for Application of Pump as Turbine: A Review

Frontiers in Energy Research, 2022
Pump as Turbine (PAT) is a technically and economically effective technology to utilize small/mini/micro/pico hydropower, especially in rural areas. There are two main subjects that influence the selection and application of PAT.
Ming Liu, Lei Tan, Shuliang Cao
doaj   +1 more source

The PHMC algorithm for simulations of dynamical fermions: I -- description and properties [PDF]

, 1998
We give a detailed description of the so-called Polynomial Hybrid Monte Carlo (PHMC) algorithm. The effects of the correction factor, which is introduced to render the algorithm exact, are discussed, stressing their relevance for the statistical ...
Alexandrou, Borrelli, Brower, Bunk, de Forcrand, de Forcrand, Duane, Edwards, Fox, Frezzotti, Frezzotti, Frezzotti, Gottlieb, Jansen, Jansen, Jansen, Jansen, Jansen, Jansen, Jegerlehner, Kalkreuter, Karl Jansen, Luscher, Lüscher, Lüscher, Lüscher, Lüscher, Lüscher, Montvay, Peardon, Press, Roberto Frezzotti, Sexton, Sheikholeslami, Sint, Symanzik, Symanzik, Symanzik, Wilson   +38 more
core   +2 more sources

Development of human monoclonal antibodies against TARM1 by yeast display

FEBS Open Bio, EarlyView.
Human monoclonal antibodies against TARM1 are generated by yeast display‐guided selection. These antibodies bind to soluble and cell‐surface forms of TARM1. Also, these antibodies exhibit agonistic activity in the NFAT‐GFP reporter assay, indicating that TARM1 signaling can be functionally modulated by antibodies and suggesting TARM1 as a potential ...
Rikio Yabe, Mayumi Saeki, Masaaki Hashiguchi, Sayaka Ono, Kazuhisa Aoki, Hidetaka Tanno   +5 more
wiley   +1 more source

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

FEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen, Qianqian Cui, Zhongyun Lan, Yingjun Wang, Shuaiying Zhao, Wenxuan Feng, Yunfeng Liu, Qiting Huang, Dongna Zhang, Jianfeng Xu   +9 more
wiley   +1 more source

MI Double Feature: Multiple Imputation to Address Nonresponse and Rounding Errors in Income Questions

Austrian Journal of Statistics, 2015
Obtaining reliable income information in surveys is difficult for two reasons. On the one hand, many survey respondents consider income to be sensitive information and thus are reluctant to answer questions regarding their income.
Joerg Drechsler, Hans Kiesl, Matthias Speidel   +2 more
doaj   +1 more source