Results 61 to 70 of about 602,649 (335)

Blinatumomab Utilization in Pediatric B‐Cell Acute Lymphoblastic Leukemia: Experience From the Mountain West

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Blinatumomab is a bispecific T‐cell engager approved for the treatment of pediatric B‐cell acute lymphoblastic leukemia (B‐ALL). Outpatient home infusion reduces hospitalization burden and optimizes resource utilization, but is logistically challenging.
Angela Parra del Riego   +10 more
wiley   +1 more source

Relationship between body-roundness index and metabolic syndrome in type 2 diabetes

open access: yesDiabetes, Metabolic Syndrome and Obesity : Targets and Therapy, 2019
Background: The present study evaluated the relationship between body-roundness index (BRI) and metabolic syndrome (MetS) in type 2 diabetes. Methods: A cross-sectional study was conducted on 585 type 2 diabetes in Qinhuangdao.
Bowei Liu   +3 more
semanticscholar   +1 more source

Assessing the effects of mitofusin 2 deficiency in the adult heart using 3D electron tomography [PDF]

open access: yes, 2017
The effects of mitofusin 2 (MFN2) deficiency, on mitochondrial morphology and the mitochondria-junctional sarcoplasmic reticulum (jSR) complex in the adult heart, have been previously investigated using 2D electron microscopy, an approach which is unable
Cabrera-Fuentes, Hector   +12 more
core   +2 more sources

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Study on the Influence of Aggregate Roundness of Reclaimed Asphalt Mixture on Its Road Performance

open access: yesBuildings, 2023
The utilization of reclaimed asphalt mixture, which combines old asphalt reclaimed material (RAP) with new aggregate, holds significant environmental benefits.
Qigui Yi, Nan Ru, Zhaoting Liu
doaj   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

A Magnetic Abrasive Finishing Process with an Auxiliary Magnetic Machining Tool for the Internal Surface Finishing of a Thick-Walled Tube

open access: yesMachines, 2022
This paper proposes a novel magnetic abrasive finishing (MAF) process that uses an auxiliary magnetic machining tool for the internal surface finishing of a thick-walled tube.
Yanzhen Yang   +7 more
doaj   +1 more source

Accuracy of roundness assessment using air gauge with the slot-shaped measuring nozzle

open access: yes, 2020
In the paper, application of the slot-shaped nozzles in the air gauges for the roundness assess-ment is discussed. Novel analysis consisted of manufacturing the slot-shaped nozzles with the outlet surfaces equal to the circular measuring nozzles.
M. Jakubowicz
semanticscholar   +1 more source

Metric trees of generalized roundness one

open access: yes, 2011
Every finite metric tree has generalized roundness strictly greater than one. On the other hand, some countable metric trees have generalized roundness precisely one.
A.N. Dranishnikov   +19 more
core   +1 more source

The Development of a Technological Processor as a Part of a Workpiece Programming System [PDF]

open access: yes, 1981
The cost of turning on NC-lathes is substantially sensative to cutting conditions. The use of optimum cutting conditions is limited by a large number of constraining factors such as chip disposal, chucking possibility, available power, required accuracy ...
Houten, F.J.A.M. van, Kals, H.J.J.
core   +3 more sources

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