Results 81 to 90 of about 602,649 (335)

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

The Selection of Cutting Speed to Prevent Deterioration of the Surface in Internal Turning of C45 Steel by Small-Diameter Boring Bars

Machines
The turning of small-diameter deep holes is usually critical when the process of machining is unstable and the use of a special boring bar is often necessary.
Tomáš Vopát, Marcel Kuruc, Boris Pätoprstý, Marek Vozár, František Jurina, Barbora Bočáková, Jozef Peterka, Augustín Görög, Róbert Straka   +8 more
doaj   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source

Improvement of surface roughness in simultaneous two turrets turning with low-frequency vibration

Journal of Advanced Mechanical Design, Systems, and Manufacturing
Low-frequency vibration cutting (VC) is a machining technology wherein a tool periodically vibrates to break cutting chips. However, VC produces tool paths that include air cuts to break up chips, which deteriorates surface roughness and roundness.
Shogo NAKAMURA, Kenichi NAKANISHI, Kenji OHARA, Yoshikatsu NAKAMURA, Chao WANG, Jiahui LIU, Shun TANAKA, Toru KIZAKI, Naohiko SUGITA   +8 more
doaj   +1 more source

Capacity of a body shape index and body roundness index to identify diabetes mellitus in Han Chinese people in Northeast China: a cross‐sectional study

Diabetic Medicine, 2018
To assess the capacity of a body shape index and body roundness index to identify people with diabetes mellitus and those with prediabetes, and to determine whether a body shape index and/or body roundness index is superior to the traditional overall ...
Qian Zhao, Kaixin Zhang, Yong Li, Qing Zhen, Jikang Shi, Yaqin Yu, Y. Tao, Yi Cheng, Yunkai Liu   +8 more
semanticscholar   +1 more source

External localization system for mobile robotics [PDF]

, 2013
We present a fast and precise vision-based software intended for multiple robot localization. The core component of the proposed localization system is an efficient method for black and white circular pattern detection.
Duckett, Tom, Faigl, Jan, Krajnik, Tomas, Mejail, Marta, Nitsche, Matias, Preucil, Libor   +5 more
core   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Towards Compensation for Servo-Control Defects in Coordinate Measuring Machines (CMMs)

Sensors
Coordinate measuring machines (CMMs) are increasingly used in manufacturing, mechanical engineering, and wherever special geometries need to be measured with the utmost precision.
Jean-François Manlay, Abdérafi Charki, Anthony Delamarre   +2 more
doaj   +1 more source

Experimental Investigation on the Geometrical Accuracy of the CNC Multi-Pass Sheet Metal Spinning Process

Journal of Manufacturing and Materials Processing, 2018
The geometrical accuracy of multi-pass sheet metal spinning products is crucial in many applications. Aerospace, petroleum, and chemical industries motivated the development of modern spun components of complicated shapes with special functionality, but ...
Mohamed Abd-Alrazzaq, Mahmoud Ahmed, Mohamed Younes   +2 more
doaj   +1 more source

Classification of Jaw Bone Cysts and Necrosis via the Processing of Orthopantomograms [PDF]

, 2013
The authors analyze the design of a method for automatized evaluation of parameters in orthopantomographic images capturing pathological tissues developed in human jaw bones.
Gescheidtova, E., Kabrda, M., Mikulka, J., Perina, V.   +3 more
core   +1 more source