Results 61 to 70 of about 1,607,761 (243)

Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology

open access: yesMolecular Oncology, EarlyView.
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié   +13 more
wiley   +1 more source

Le concept de routine dans la socio-anthropologie de la vie quotidienne

open access: yesEspace populations sociétés, 2015
The routine concerns the institutional structuring of time and personal automatisms that everyone put in place, both to protect themselves from threatening uncertainty as to avoid the weight of small permanent decisions, freeing vital energy and possible
Salvador Juan
doaj   +1 more source

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

open access: yesMolecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller   +17 more
wiley   +1 more source

Aperture a cambiamenti nel discorso: il caso di Dario

open access: yesDidattica della Matematica
Usando la prospettiva comognitiva, l’articolo presenta la nozione di profilo di apprendimento matematico e mostra come possa essere identificato attraverso l’analisi di un’intervista.
Chiara Bonadiman, Elena Macchioni
doaj   +1 more source

Charisma and Routine: Shaping the Memory of Brother Richard and Joan of Arc

open access: yesReligions, 2012
The extraordinary life and fate of Joan of Arc are well known; so is her association with the prophetic preacher, Brother Richard, who predicted the Apocalypse. Less well explained is why contemporaries initially took such an interest in this association,
Andrew Brown
doaj   +1 more source

Monitoring of circulating tumor DNA allows early detection of disease relapse in patients with operable breast cancer

open access: yesMolecular Oncology, EarlyView.
Monitoring circulating tumor DNA (ctDNA) in patients with operable breast cancer can reveal disease relapse earlier than radiology in a subset of patients. The failure to detect ctDNA in some patients with recurrent disease suggests that ctDNA could serve as a supplement to other monitoring approaches.
Kristin Løge Aanestad   +35 more
wiley   +1 more source

Is routine histopathology of tonsil specimen necessary?

open access: yesAfrican Journal of Paediatric Surgery, 2011
Background: Tonsillar diseases are common in paediatric and adult otolaryngological practice. These diseases require tonsillectomy. Specimens are subjected to histopathology routinely in my institution for fear of infections and tumour without ...
Agida S Adoga   +2 more
doaj   +1 more source

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

open access: yesMolecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix   +13 more
wiley   +1 more source

Routines of Riparian Women of the Amazon Region: Activities and Roles in the Family, at Work and in the Community

open access: yesInterpersona: An International Journal on Personal Relationships, 2015
The aim of this study was to investigate the perception of the routines of women who live in Amazon riverside communities, identifying the roles and activities related to domestic work, açaí gathering and actions in community associations.
Neuzeli Maria de Almeida Pinto   +2 more
doaj   +1 more source

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

open access: yesMolecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala   +15 more
wiley   +1 more source

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