Results 61 to 70 of about 3,578,337 (334)

Examination of the Circle Spline Routine [PDF]

open access: yes, 1985
The Circle Spline routine is currently being used for generating both two and three dimensional spline curves. It was developed for use in ESCHER, a mesh generating routine written to provide a computationally simple and efficient method for building ...
Dolin, R. M., Jaeger, D. L.
core   +1 more source

Redox‐dependent binding and conformational equilibria govern the fluorescence decay of NAD(P)H in living cells

open access: yesFEBS Letters, EarlyView.
In this work, we reveal how different enzyme binding configurations influence the fluorescence decay of NAD(P)H in live cells using time‐resolved anisotropy imaging and fluorescence lifetime imaging microscopy (FLIM). Mathematical modelling shows that the redox states of the NAD and NADP pools govern these configurations, shaping their fluorescence ...
Thomas S. Blacker   +8 more
wiley   +1 more source

Evaluation of Four Rapid Antigen Tests for Detection of SARS-CoV-2 virus

open access: yesOman Medical Journal, 2021
Objectives: Considering the increasing, significant burden that coronavirus disease 2019 (COVID-19) imposes on the healthcare system, the need for simple, rapid, and affordable diagnostic tests to support the existing costly and demanding polymerase ...
Sulaiman Al-Alawi   +8 more
doaj   +1 more source

Modeling material failure with a vectorized routine [PDF]

open access: yes, 1984
The computational aspects of modelling material failure in structural wood members are presented with particular reference to vector processing aspects.
Cramer, S. M., Goodman, J. R.
core   +1 more source

Randomised controlled trial and economic evaluation of a chest pain observation unit compared with routine care [PDF]

open access: yes, 2004
Objectives To measure the effectiveness and cost effectiveness of providing care in a chest pain observation unit compared with routine care for patients with acute, undifferentiated chest pain.
Angelini, K.   +11 more
core   +2 more sources

Neutrophil deficiency increases T cell numbers at the site of tissue injury in mice

open access: yesFEBS Letters, EarlyView.
In wild‐type mice, injury or acute inflammation induces neutrophil influx followed by macrophage accumulation. Mcl1ΔMyelo (neutrophil‐deficient) mice lack neutrophils, and in response to muscle injury show fewer macrophages and exhibit strikingly elevated T‐cell numbers, primarily non‐conventional “double‐negative” (DN) αβ and γδ T cells.
Hajnalka Halász   +6 more
wiley   +1 more source

An Individual in Society: Self-Identification Processes in Modern Concepts of Identity

open access: yesJournal of Modern Science, 2018
Objectives Paper contains analysis of several sociological, social-psychological and philosophical concepts of individual identity from the last quarter of 20th c. and the turn of 21st c.
Kateryna Novikova
doaj   +1 more source

Incorporating Naloxone Education Into Routine Primary Care [PDF]

open access: yes, 2018
Opioid overdoses are a growing public health concern in Vermont and nationwide. Naloxone can save the life of someone who overdoses, if those around them know how to use it.
Goldberg, Eli
core   +1 more source

A working model for cytoplasmic assembly of H/ACA snoRNPs

open access: yesFEBS Letters, EarlyView.
Dyskerin is the component of nuclear H/ACA ribonucleoproteins (RNPs) endowed with pseudouridine synthase catalytic activity. Two isoforms of human dyskerin have been characterized: the abundant Iso1, mainly nuclear, and the shorter Iso3, mainly cytoplasmic but occasionally imported into nuclei.
Alberto Angrisani, Maria Furia
wiley   +1 more source

C9orf72 ALS‐causing mutations lead to mislocalization and aggregation of nucleoporin Nup107 into stress granules

open access: yesFEBS Letters, EarlyView.
Mutations in the C9orf72 gene represent the most common genetic cause of amyotrophic lateral sclerosis (ALS), a fatal neurodegenerative disease. Using patient‐derived neurons and C. elegans models, we find that the nucleoporin Nup107 is dysregulated in C9orf72‐associated ALS. Conversely, reducing Nup107 levels mitigates disease‐related changes.
Saygın Bilican   +7 more
wiley   +1 more source

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