Results 51 to 60 of about 131,052 (322)

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

open access: yesFEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang   +9 more
wiley   +1 more source

Outlier detection based energy efficient and reliable routing protocol using deep learning algorithm

open access: yesCognitive Computation and Systems, 2023
Wireless sensor network have also played a vital role in the observation and management of agricultural land in terms of climate, water usage, crops, etc.
P. Jasmine Lizy, N. Chenthalir Indra
doaj   +1 more source

Short‐term actions of epigalocatechin‐3‐gallate in the liver: a mechanistic insight into hypoglycemic and potential toxic effects

open access: yesFEBS Open Bio, EarlyView.
Epigallocatechin‐3‐gallate (EGCG) acutely inhibited gluconeogenesis and enhanced glycolysis, glycogenolysis, and fatty acid oxidation in perfused rat livers. Mechanistic assays revealed mitochondrial uncoupling, inhibition of pyruvate carboxylation and glucose‐6‐phosphatase, shift of NADH/NAD+ ratios toward oxidation, and loss of membrane integrity ...
Carla Indianara Bonetti   +8 more
wiley   +1 more source

Autophagosome marker, LC3, is released extracellularly via several distinct pathways

open access: yesFEBS Open Bio, EarlyView.
This study establishes a novel HiBiT‐tagging system for ultrasensitive detection of LC3, revealing multiple pathways for its extracellular secretion. It demonstrates that LC3 is released via both autophagy‐dependent and ‐independent mechanisms, including a novel route for nonlipidated LC3‐I.
Koki Saito   +3 more
wiley   +1 more source

A Secure Link State Routing Protocol for NDN

open access: yesIEEE Access, 2018
The Named-data Link State Routing protocol (NLSR) is a protocol for intra-domain routing in Named Data Networking (NDN). It is an application level protocol similar to many IP routing protocols, but NLSR uses NDN's interest/data packets to disseminate ...
Lan Wang   +5 more
doaj   +1 more source

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

open access: yesFEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani   +6 more
wiley   +1 more source

Novel ASON routing implementation

open access: yesTongxin xuebao, 2006
An OSPF-based ASON routing implementation was proposed.In the implementation a wavelength LSA and network node LSA were extended to distribute wavelength and topology information.The topology was discovered automatically and routing messages were ...
LI Jian   +3 more
doaj   +2 more sources

Pioglitazone plus (−)‐epigallocatechin gallate: a novel approach to enhance osteogenic performance in aged bone marrow mesenchymal stem cells

open access: yesFEBS Open Bio, EarlyView.
Aged human bmMSCs are seeded in the scaffold. Osteoblastic induction can slightly increase cell's bone‐forming activity to produce bone‐like tissues, shown as the sporadic xylenol orange‐stained spots (the lower left image). Notably, pioglitazone plus EGCG co‐treatment dramatically increases cell's bone‐forming activity and bone‐like tissue production (
Ching‐Yun Chen   +6 more
wiley   +1 more source

Using the redistribution between routing protocols to find best route

open access: yesمجلة علوم ذي قار, 2019
Routers can forward packets through an internetwork by maintaining routing information in a database called a routing table. The routing table typically contains the address of all known networks and routing information about that network such as ...
Aqeel Hamad
doaj  

Analisa Proses Routing Ripv1, Ripv2, Ripng, antara Model Ipv4 dengan Ipv6 pada Jaringan Data PT. Pertamina Ru II Dumai [PDF]

open access: yes, 2016
The development of telecommunications today make the need for communication of data quickly and efficiently is also one of his company besar.IPv4 scale to support 32-bit addressing and developed IPv6 supports up to 128 -bit addressing and also developed ...
Adhil, I. F. (Irsan)   +2 more
core  

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