Results 151 to 160 of about 3,625,328 (233)

ROX (Respiratory rate–OXygenation) index to predict early response to high‐flow nasal cannula therapy in infants with viral bronchiolitis

open access: yes
International audienceAbstract Introduction High‐flow nasal cannula (HFNC) is commonly used as first step respiratory support in infants with moderate‐to‐severe acute viral bronchiolitis (AVB).
Brosssier, David   +8 more
core   +1 more source

Does Living with a Wild River Improve Mental Health and Well‐Being? A Case Study of Blue‐Space Interaction and Stress Reduction in Southern Albania

open access: yesTijdschrift voor Economische en Sociale Geografie, EarlyView.
Abstract The effect of natural blue space on subjective well‐being and self‐perceived stress among residents of Përmet, Albania (N = 203), with 80.3 per cent of whom reside within 1 km of the Vjosa River was examined. Three exposure indicators – visit frequency, proximity and time spent in the river surroundings – were focused on using the PYER ...
Elena Kokthi   +3 more
wiley   +1 more source

Heat treatment combined with hybrid exercises retraining mitigates cellular markers of protein turnover after hindlimb suspension in male mice: A pilot study

open access: yesExperimental Physiology, EarlyView.
Abstract Recent evidence suggests that heat treatment (HT) and resistance training can limit skeletal muscle mass loss during immobilization. However, the effects of repeated HT sessions combined with hybrid exercises (EX), which promote both endurance and resistance responses, on muscle protein turnover following hindlimb unloading (HU) remain ...
Tom Normand‐Gravier   +9 more
wiley   +1 more source

Mitochondrial capacities and quality control following short‐ and long‐term weight restoration after simulated anorexia nervosa

open access: yesExperimental Physiology, EarlyView.
Abstract Anorexia nervosa (AN) is a psychiatric disorder characterized by prolonged caloric restriction and skeletal muscle atrophy. Mitochondrial health is a key mediator of muscle function, yet the role of mitochondria during AN and following weight regain has not been investigated. The objective of this study was to evaluate mitochondrial capacities
Megan E. Rosa‐Caldwell   +12 more
wiley   +1 more source

Placental mitochondrial metabolic adaptation maintains cellular energy balance in pregnancy complicated by gestational hypoxia

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Placental mitochondrial adaptation to gestational hypoxia. Hypoxic pregnancy in sheep increases placental insulin like growth factor 2 (IGF2) signalling (1), which is associated with a shift in capacity away from β‐oxidation (2) and complex I‐mediated respiration (3), while maintaining total oxidative phosphorylation capacity (4).
Wen Tong   +18 more
wiley   +1 more source

Genetic and Pharmacologic Inhibition of Myostatin Restores Muscle Mass in a Dynamin 2‐Related Centronuclear Myopathy Mouse Model

open access: yesJournal of Cachexia, Sarcopenia and Muscle, Volume 17, Issue 5, October 2026.
ABSTRACT Background Autosomal dominant centronuclear myopathy (ADCNM), most commonly caused by mutations in the dynamin 2 (DNM2) gene, is a rare congenital myopathy characterized by progressive muscle weakness and atrophy. Myostatin, a key negative regulator of skeletal muscle mass, has shown therapeutic potential in several models of neuromuscular ...
Durieux Anne‐Cécile   +20 more
wiley   +1 more source

Mitochondrial Respiration in Peripheral Blood Cells Links to Metabolic Flexibility and Physical Performance in Ageing

open access: yesJournal of Cachexia, Sarcopenia and Muscle, Volume 17, Issue 5, October 2026.
ABSTRACT Background Age‐related declines in energy metabolism, muscle strength and physical performance have been linked to lower mitochondrial respiratory capacity. Peripheral blood mononuclear cell (PBMC) respiration offers a minimally invasive marker of systemic bioenergetics, yet its relationship to whole‐body metabolic flexibility remains unclear.
Donna Li   +9 more
wiley   +1 more source

Prognostication of COVID-19 patients using ROX index and CURB-65 score - A retrospective observational study. [PDF]

open access: yesJ Family Med Prim Care, 2022
Arora P   +7 more
europepmc   +1 more source

ATP Release and Purinergic Signaling Potentiate β‐Adrenergic Effects on Brown Adipocytes

open access: yesActa Physiologica, Volume 242, Issue 10, October 2026.
ABSTRACT Aim Brown adipose tissue (BAT) specializes in energy consumption and thermogenesis in response to cold stress. Brown adipocytes (BA) express purinergic receptors, yet little is known about the source of extracellular ATP and the role of purinergic signaling, and the potential interaction with β‐adrenergic signaling.
Marco Tozzi   +8 more
wiley   +1 more source

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