The Environmental Exposome and Age-Related Macular Degeneration: Oxidative Stress as a Molecular Link. [PDF]
Antioxidants (Basel)Mimura T, Noma H.
europepmc +1 more source
Diabetic Medicine, EarlyView.Abstract Introduction Older adults with diabetes have an increased risk of falls due to neuropathy, impaired bone health and cardiovascular disease, resulting in significant morbidity and mortality. Conventional fall‐prevention programmes primarily target strength and balance, while cognitive‐motor integration, essential for safe mobility in complex ...
Aksayan Arunanthy Mahalingasivam +4 more
wiley +1 more source
Brazilian Red Propolis Extract-Loaded Colloidal Systems Derived from Microemulsion Compositions: Physicochemical, Antioxidant, and Antileishmanial Properties. [PDF]
PharmaceuticsCosta SPM +9 more
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Rethinking diabetic retinopathy: Homeostatic mechanisms for retinal clearance
Diabetic Medicine, EarlyView.In the healthy retina, balanced production and clearance of metabolic waste and fluid maintain retinal homeostasis and normal visual function. Diabetes disrupts this balance, increasing the accumulation of metabolic waste products, including advanced glycation end products (AGEs) and advanced lipoxidation end products (ALEs), while impairing waste and ...
Karis Little +7 more
wiley +1 more source
The FEBS Journal, EarlyView.Vitamin B6 is a critical molecule for plant metabolism and development. Rsr4‐1, a loss‐of‐function mutant in a vitamin B6 biosynthesis gene, has a distinct short root phenotype. Here we describe five novel suppressor mutants with an rsr4‐1 background that have normalized root growth and distinct phenotypic and molecular characteristics, representing a ...
Marcelina Parra +4 more
wiley +1 more source
Timeline of Achieving a Differentiated RPE Phenotype and Specialised Metabolism of ARPE-19 Cells Under Physiologically Relevant-Inducing Culture Conditions. [PDF]
CellsMatei IV +5 more
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Relative Peer Quality and 10‐K Readability
Journal of Business Finance &Accounting, EarlyView.ABSTRACT This study examines the impact of the relative managerial quality of executives’ compensation peers on the readability of narrative disclosures in focal firms’ 10‐K reports. We use the fraction of peers with greater managerial ability scores than the reporting firm to measure the reporting firm's relative peer quality (RPQ).
Xiaohua (Stephen) Wu +2 more
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Journal of Diabetes Investigation, EarlyView.ABSTRACT Objective To explore the expression of the deubiquitinase (DUB) USP25 in diabetic retinopathy (DR) and its mechanistic role in regulating ferroptosis. Methods Bioinformatics was used to screen for DR‐related DUB candidate genes. USP25 expression was validated in a streptozotocin‐induced diabetic mouse model and high glucose (HG)‐treated ARPE ...
Yanjun Gao +3 more
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SEMA3A in Proliferative Vitreoretinopathy: Exogenous Activity, Endogenous Regulation, and the MicroRNA Hypothesis. [PDF]
BiomedicinesWang B, Li S, Cao Y, Sun A, Li M, Qu J.
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20th Anniversary of human‐induced pluripotent stem cells and the role of microscopy
Journal of Microscopy, EarlyView.Abstract It has been 20 years since the pioneering work of Shinya Yamanaka and Kazutoshi Takahashi at Kyoto University led to the first successful generation of induced pluripotent stem cells (iPSCs) from mouse embryonic and adult fibroblast cells. iPSCs have the capacity to differentiate into any type of cell in the human body, and as such, they have ...
Philomena Hallford +3 more
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