Results 211 to 220 of about 77,663 (265)
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Transplantation of the RPE in AMD
Progress in Retinal and Eye Research, 2007The retinal pigment epithelium (RPE) maintains retinal function as the metabolic gatekeeper between photoreceptors (PRs) and the choriocapillaries. The RPE and Bruch's membrane (BM) suffer cumulative damage over lifetime, which is thought to induce age-related macular degeneration (AMD) in susceptible individuals.
Susanne, Binder +3 more
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Progress in Retinal and Eye Research, 2007
In close interaction with photoreceptors, the retinal pigment epithelium (RPE) plays an essential role for visual function. The analysis of RPE functions, specifically ion channel functions, provides a basis to understand many degenerative diseases of the retina.
Sönke, Wimmers +2 more
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In close interaction with photoreceptors, the retinal pigment epithelium (RPE) plays an essential role for visual function. The analysis of RPE functions, specifically ion channel functions, provides a basis to understand many degenerative diseases of the retina.
Sönke, Wimmers +2 more
openaire +2 more sources
The RPEs of RBCs and other DSGEs
Journal of Economic Dynamics and Control, 2021zbMATH Open Web Interface contents unavailable due to conflicting licenses.
David Evans +2 more
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Filamentous RPE Hyperplasia in Combined Hamartoma of the Retina and RPE
JAMA OphthalmologyThis case report describes a diagnosis of combined hamartoma of the retina and retinal pigment epithelium (RPE) with filamentous RPE hyperplasia in a female child with a history of amblyopia, myopia, and exotropia of the affected eye.
Jason, Fan +2 more
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A2E, a Fluorophore of RPE Lipofuscin: Can It Cause RPE Degeneration?
2003In atrophic age-related macular degeneration (AMD) and Stargardt disease, the death of retinal pigment epithelial (RPE) cell death leads to photoreceptor cell degeneration and visual impairment. Nevertheless, the cause of RPE atrophy is poorly understood.
Janet R, Sparrow +7 more
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2020
Laser is widely used for treatment of retinal diseases. A laser induces retinal tissue reactions both in vitro and in vivo and is therefore used in multiple research and clinical applications. For a better understanding, it is important to understand and distinguish between different laser-tissue interactions.
Claus von der Burchard, Johann Roider
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Laser is widely used for treatment of retinal diseases. A laser induces retinal tissue reactions both in vitro and in vivo and is therefore used in multiple research and clinical applications. For a better understanding, it is important to understand and distinguish between different laser-tissue interactions.
Claus von der Burchard, Johann Roider
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Oxidative damage and protection of the RPE
Progress in Retinal and Eye Research, 2000This review provides a model for the role of oxidative stress in the etiology of age-related macular degeneration (AMD). Epidemiological studies of diet, environmental and behavioral risk factors suggest that oxidative stress is a contributing factor of AMD.
J, Cai +4 more
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2020
The RPE represents one of the two major cell types in the retina that have been targeted by gene therapy, next to the photoreceptors. Following subretinal delivery, viral vectors, such as adeno-associated virus (AAV), lentivirus or adenovirus based vectors, or nanoparticles deliver genetic material into this cell type, allowing robust and long term ...
Knut Stieger, Birgit Lorenz
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The RPE represents one of the two major cell types in the retina that have been targeted by gene therapy, next to the photoreceptors. Following subretinal delivery, viral vectors, such as adeno-associated virus (AAV), lentivirus or adenovirus based vectors, or nanoparticles deliver genetic material into this cell type, allowing robust and long term ...
Knut Stieger, Birgit Lorenz
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Acta Ophthalmologica, 2015
SummaryThe retinal pigment epithelium (RPE)/ photoreceptor complex constitutes the choroid, bruch's membrane and the photoreceptor outer segments. The RPE interacts with bruch's membrane and the photoreceptors, which it faces across the subretinal space. In these interactions the RPE acts as three types of cell ‐ epithelium, macrophage, and glia. There
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SummaryThe retinal pigment epithelium (RPE)/ photoreceptor complex constitutes the choroid, bruch's membrane and the photoreceptor outer segments. The RPE interacts with bruch's membrane and the photoreceptors, which it faces across the subretinal space. In these interactions the RPE acts as three types of cell ‐ epithelium, macrophage, and glia. There
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Acta Ophthalmologica Scandinavica, 2007
Abstract Purpose: Most cellular proteins are continuously synthesized and degraded within the life‐span of a cell. Two major systems take care of protein degradation in eukaryotic cells: the proteasomes, which degrade the vast majority of long‐ and short‐lived normal and abnormal intracellular proteins and the lysosomes, which degrade membrane and ...
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Abstract Purpose: Most cellular proteins are continuously synthesized and degraded within the life‐span of a cell. Two major systems take care of protein degradation in eukaryotic cells: the proteasomes, which degrade the vast majority of long‐ and short‐lived normal and abnormal intracellular proteins and the lysosomes, which degrade membrane and ...
openaire +1 more source