Results 31 to 40 of about 137,298 (354)
Not All Stressors Are Equal: Mechanism of Stressors on RPE Cell Degeneration
Frontiers in Cell and Developmental Biology, 2020 Age-related macular degeneration (AMD) is a major cause of irreversible blindness among the elderly population. Dysfunction and degeneration of the retinal pigment epithelial (RPE) layer in the retina underscore the pathogenesis of both dry and wet AMD ...
Yao Tong, Shusheng Wang
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Redox Biology, 2019 Age-related macular degeneration (AMD) is the leading cause of vision loss in the western world. Recent evidence suggests that RPE and photoreceptors have an interconnected metabolism and that mitochondrial damage in RPE is a trigger for degeneration in ...
Emily E. Brown +4 more
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Stem Cell Reports, 2020 Summary Recent trials of retinal pigment epithelium (RPE) transplantation for the treatment of disorders such as age-related macular degeneration have been promising. However, limitations of existing strategies include the uncertain survival of RPE cells
Zengping Liu +14 more
semanticscholar +1 more source
Autophagy in the eye: from physiology to pathophysiology
Autophagy Reports, 2023 Autophagy is a catabolic self-degradative pathway that promotes the degradation and recycling of intracellular material through the lysosomal compartment. Although first believed to function in conditions of nutritional stress, autophagy is emerging as a
Paloma B. Liton +15 more
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The Intersection of Serine Metabolism and Cellular Dysfunction in Retinal Degeneration
Cells, 2020 In the past, the importance of serine to pathologic or physiologic anomalies was inadequately addressed. Omics research has significantly advanced in the last two decades, and metabolomic data of various tissues has finally brought serine metabolism to ...
Tirthankar Sinha +3 more
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Frontiers in Neuroscience, 2017 Purpose: The aim of this review is to (1) retrieve all data validating the Session-rating of perceived exertion (RPE)-method using various criteria, (2) highlight the rationale of this method and its ecological usefulness, and (3) describe factors that ...
M. Haddad +4 more
semanticscholar +1 more source
Development-related mitochondrial properties of retinal pigment epithelium cells derived from hEROs [PDF]
International Journal of Ophthalmology, 2021 AIM: To explore the temporal mitochondrial characteristics of retinal pigment epithelium (RPE) cells obtained from human embryonic stem cells (hESC)-derived retinal organoids (hEROs-RPE), to verify the optimal period for using hEROs-RPE as donor cells ...
Hao-Jue Xu +3 more
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A comparison of the effects of Carbohydrate and Carbohydrate-Protein supplements on Performance and Selected Immune markers during intermittent soccer activities [PDF]
فیزیولوژی ورزش و فعالیت بدنی, 2010 Background and Aim: The main purpose of this study a comparison of the effects of Carbohydrate andCarbohydrate-Protein supplements on Performance and Selected Immune markers during intermittent socceractivities. Materials and Methods: Towenty four soccer
هادی قائدی +4 more
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Dysfunctional autophagy in RPE, a contributing factor in age-related macular degeneration
Cell Death and Disease, 2017 Age-related macular degeneration (AMD) is a devastating neurodegenerative disease and a major cause of blindness in the developed world. Owing to its complexity and the lack of an adequate human model that recapitulates key aspects of the disease, the ...
N. Golestaneh +4 more
semanticscholar +1 more source
Biological effects of cigarette smoke in cultured human retinal pigment epithelial cells. [PDF]
, 2012 The goal of the present study was to determine whether treatment with cigarette smoke extract (CSE) induces cell loss, cellular senescence, and extracellular matrix (ECM) synthesis in primary human retinal pigment epithelial (RPE) cells. Primary cultured
Johannes Burger +8 more
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