Results 31 to 40 of about 74,456 (268)

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

FEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour, Christine Volmert, Valentina Piano   +2 more
wiley   +1 more source

Fenofibrate Ameliorates Retinal Pigment Epithelium Injury Induced by Excessive Fat Through Upregulation of PI3K/AKT Signaling

Drug Design, Development and Therapy, 2023
Xue Wang,1– 3 Xiaomei Liu,2 Radouil Tzekov,4 Chaofeng Yu,1 Jiasong Yang,1,5 Yuliang Feng,1 Yajun Wu,1 Yali Xu,1 Shiying Li,6 Wensheng Li1,5,7 1Aier School of Ophthalmology, Central South University, Changsha, People’s Republic of China; 2Suzhou Institute
Wang X, Liu X, Tzekov R, Yu C, Yang J, Feng Y, Wu Y, Xu Y, Li S, Li W   +9 more
doaj  

Does Long‐Term Lower Extremity Strength Training in Adults With Knee Osteoarthritis and Varus Alignment Reduce Knee Joint Loading During Gait?

Arthritis Care &Research, EarlyView.
Objective We examined whether 18 months of strength training in individuals with knee varus alignment and medial tibiofemoral osteoarthritis (OA) reduced knee joint loads during walking compared to an attention control group. Methods This study was a secondary analysis of a randomized clinical trial that compared the effects of strength training to a ...
Stephen P. Messier, Matthew N. Vigliotti, Paige E. Rice, Brian Pietrosimone, Shannon L. Mihalko, Edward H. Ip, Richard F. Loeser, David J. Hunter, Ali Guermazi, Ryan Hill, Santiago Saldana, Kim L. Bennell, Paul DeVita   +12 more
wiley   +1 more source

Effect of Progressive Fatigue on Session RPE [PDF]

Journal of Functional Morphology and Kinesiology, 2020
Rating of perceived exertion (RPE) and session RPE (sRPE) are reliable tools for predicting exercise intensity and are alternatives to more technological and physiological measurements, such as blood lactate (HLa) concentration, oxygen consumption and heart rate (HR).
Fusco A., Sustercich W., Edgerton K., Cortis C., Jaime S. J., Mikat R. P., Porcari J. P., Foster C.   +7 more
openaire   +3 more sources

Multidimensional Cellular Micro‐Compartments to Model Invasive Lobular Carcinoma Dormancy

Advanced Healthcare Materials, EarlyView.
Invasive lobular carcinoma (ILC) is an understudied subtype of breast cancer that is susceptible to late recurrences. In this study, micro‐compartmentalization techniques spanning multiple dimensions, including 2D, pseudo‐3D, and 3D, are integrated to uncover the mechanisms underlying ILC dormancy, revealing the central role of p27Kip1.
Xilal Y. Rima, Sarmila Majumder, Divya S. Patel, Chunyu Hu, Hong Li, Xin Huang, Kim Truc Nguyen, Jacob Doon‐Ralls, Chiranth K. Nagaraj, Mangesh D. Hade, Setty M. Magaña, Eswar Shankar, Xiaoli Zhang, Daniel G. Stover, Bhuvaneswari Ramaswamy, Eduardo Reátegui   +15 more
wiley   +1 more source

Comparative study on nutrient availability and growth of tomato (Lycopersicon esculentum) seedlings in soils amended with palm oil mill effluent and rubber processing effluents

Cogent Food & Agriculture, 2020
This study investigates the effect of the palm oil mill effluent (POME) and rubber processing effluent (RPE) on some soil properties and growth of tomato (Lycopersicum esculentum) seedlings.
M. Maliki, E. U. Ikhuoria, S. O. Omorogbe, M. O. Ekebafe   +3 more
doaj   +1 more source

Engineering Concentration‐Dependent Intravitreal Mobility via Cyclic Arginine‐Enriched Nanocarrier Surface Modification: In Vivo Proof‐of‐Concept in a Porcine Large Animal Model

Advanced Healthcare Materials, EarlyView.
In this study, Hammer et al. highlight cyclic‐arginine surface engineering as a highly biocompatible, controllable, and concentration‐dependent regulator of intravitreal nanoparticle mobility in vivo in a translational large animal model. The cyclic arginine surface‐modification supports the development of next‐generation biomaterials for long‐acting ...
Maximilian Hammer, Bryan Calder Ackermann, Anna Stoß, Niklas Junker, Ludwig Geisweid, Sabrina Wohlfart, Jonathan Herth, Simon William Pohl, Manuel Ben Böhmann, André Schulz, Victor Aristide Augustin, Gerd Uwe Auffarth, Philipp Uhl   +12 more
wiley   +1 more source

Regulated secretion of complement factor H by RPE and its role in RPE migration [PDF]

Graefe's Archive for Clinical and Experimental Ophthalmology, 2009
Variants in the gene for complement factor H (CFH) have been implicated as a major risk factor for the development of age-related macular degeneration (AMD). Little is known, however, about the factors regulating local expression and secretion of CFH by retinal pigment epithelial cells (RPE).Cultured human early passage RPE cells, highly differentiated,
Yeong Hoon, Kim, Shikun, He, Satoru, Kase, Mizuki, Kitamura, Stephen J, Ryan, David R, Hinton   +5 more
openaire   +2 more sources

Inhibition of VEGF‐Induced Angiogenesis and Vascular Leakage by Bicistronic Co‐Expression of Aflibercept and COMP‐Ang1

Advanced Healthcare Materials, EarlyView.
A bicistronic rAAV8 vector encoding Aflibercept (Afb) and COMP‐cAng1 simultaneously coordinates VEGF clearance and Tie2‐mediated vessel maturation. In a 3D angiogenesis‐on‐a‐chip model, rAAV8‐Afb/cAng1 effectively reverses pathological barrier breakdown under clinical disease‐mimicking challenges.
Bong‐Kyu Kim, Jaehong Min, Sang‐Hee Park, Subeen Shin, Sangbin Yu, Jeong‐Eun Park, Sujin Kim, Wooju Park, Jihoon Ko, Sunjong Kwon   +9 more
wiley   +1 more source

A Conservatıve Treatment Approach In A Sceletal Class III Case. A Case Report

Turkish Journal of Orthodontics, 1995
Rapid maxillary expansion (R.M.E.) has a special place in orthodontic treatments. It is based on the principle of opening of the sutura palatina media. Among indications of the R.M.E. were collaps due to maxillary deficency, nasal insufficiency and cleft
Enis Güray, Ali İhya Karaman
doaj   +1 more source