Results 41 to 50 of about 208,874 (328)

Geographic atrophy of the macula

open access: yesDelta Journal of Ophthalmology, 2015
Geographic atrophy of the macula is a late form of dry AMD. Changes found on optical coherence tomography imaging (OCT) include Retinal Pigment Epithelium (RPE) atrophic changes and window defects, with a pronounced photorecetor layer damage.
Alaa M Fadel
doaj   +1 more source

The Intersection of Serine Metabolism and Cellular Dysfunction in Retinal Degeneration

open access: yesCells, 2020
In the past, the importance of serine to pathologic or physiologic anomalies was inadequately addressed. Omics research has significantly advanced in the last two decades, and metabolomic data of various tissues has finally brought serine metabolism to ...
Tirthankar Sinha   +3 more
doaj   +1 more source

A requirement for STAG2 in replication fork progression creates a targetable synthetic lethality in cohesin-mutant cancers. [PDF]

open access: yes, 2019
Cohesin is a multiprotein ring that is responsible for cohesion of sister chromatids and formation of DNA loops to regulate gene expression. Genomic analyses have identified that the cohesin subunit STAG2 is frequently inactivated by mutations in cancer.
Ashworth, Alan   +4 more
core   +2 more sources

Impaired ABCA1/ABCG1-mediated lipid efflux in the mouse retinal pigment epithelium (RPE) leads to retinal degeneration

open access: yeseLife, 2019
Age-related macular degeneration (AMD) is a progressive disease of the retinal pigment epithelium (RPE) and the retina leading to loss of central vision.
F. Storti   +21 more
semanticscholar   +1 more source

A comparison of the effects of Carbohydrate and Carbohydrate-Protein supplements on Performance and Selected Immune markers during intermittent soccer activities [PDF]

open access: yesفیزیولوژی ورزش و فعالیت بدنی, 2010
Background and Aim: The main purpose of this study a comparison of the effects of Carbohydrate andCarbohydrate-Protein supplements on Performance and Selected Immune markers during intermittent socceractivities. Materials and Methods: Towenty four soccer
هادی قائدی   +4 more
doaj   +1 more source

Inspiratory muscle training and its effect on indices of physiological and perceived stress during incremental walking exercise in normobaric hypoxia [PDF]

open access: yes, 2014
This study evaluated the effects of inspiratory muscle training (IMT) on inspiratory muscle fatigue (IMF) and physiological and perceptual responses during trekking-specific exercise. An 8-week IMT program was completed by 21 males (age 32.4 ± 9.61 years,
Bartesaghi, M   +8 more
core   +1 more source

Carbohydrate supplementation and psychophysiological responses during moderate exercise in hypoxia

open access: yesJournal of the International Society of Sports Nutrition, 2020
Background Rating of Perceived Exertion (RPE) is a subjective scale to monitor overload and fatigue during exercise. Hypoxia may worsen the perception of fatigue, compromising the self-reported perception of effort and increasing RPE.
E. Tavares-Silva   +5 more
doaj   +1 more source

Support Your Recovery Needs (SYRN) – a systemic approach to improve sport performance

open access: yesBiomedical Human Kinetics, 2023
Study aim: The aim of this study was to present the Support Your Recovery Needs (SYRN) recovery system based on scientifically confirmed methods, addressing the needs of athletes based on their subjective feelings of fatigue after training or competition.
Adamczyk Jakub Grzegorz
doaj   +1 more source

In-season training load quantification of one-, two- and three-game week schedules in a top European professional soccer team [PDF]

open access: yes, 2019
Top European soccer teams that play in UEFA competitions often participate in one, two- or three-games per week. Therefore, it is necessary to ensure optimal match-day performance and full recovery.
Brito, João   +7 more
core   +1 more source

Oxidative stress-mediated TXNIP loss causes RPE dysfunction

open access: yesExperimental and Molecular Medicine, 2019
The disruption of the retinal pigment epithelium (RPE), for example, through oxidative damage, is a common factor underlying age-related macular degeneration (AMD).
Min Ji Cho   +11 more
semanticscholar   +1 more source

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