Geographic atrophy of the macula
Geographic atrophy of the macula is a late form of dry AMD. Changes found on optical coherence tomography imaging (OCT) include Retinal Pigment Epithelium (RPE) atrophic changes and window defects, with a pronounced photorecetor layer damage.
Alaa M Fadel
doaj +1 more source
The Intersection of Serine Metabolism and Cellular Dysfunction in Retinal Degeneration
In the past, the importance of serine to pathologic or physiologic anomalies was inadequately addressed. Omics research has significantly advanced in the last two decades, and metabolomic data of various tissues has finally brought serine metabolism to ...
Tirthankar Sinha +3 more
doaj +1 more source
A requirement for STAG2 in replication fork progression creates a targetable synthetic lethality in cohesin-mutant cancers. [PDF]
Cohesin is a multiprotein ring that is responsible for cohesion of sister chromatids and formation of DNA loops to regulate gene expression. Genomic analyses have identified that the cohesin subunit STAG2 is frequently inactivated by mutations in cancer.
Ashworth, Alan +4 more
core +2 more sources
Age-related macular degeneration (AMD) is a progressive disease of the retinal pigment epithelium (RPE) and the retina leading to loss of central vision.
F. Storti +21 more
semanticscholar +1 more source
A comparison of the effects of Carbohydrate and Carbohydrate-Protein supplements on Performance and Selected Immune markers during intermittent soccer activities [PDF]
Background and Aim: The main purpose of this study a comparison of the effects of Carbohydrate andCarbohydrate-Protein supplements on Performance and Selected Immune markers during intermittent socceractivities. Materials and Methods: Towenty four soccer
هادی قائدی +4 more
doaj +1 more source
Inspiratory muscle training and its effect on indices of physiological and perceived stress during incremental walking exercise in normobaric hypoxia [PDF]
This study evaluated the effects of inspiratory muscle training (IMT) on inspiratory muscle fatigue (IMF) and physiological and perceptual responses during trekking-specific exercise. An 8-week IMT program was completed by 21 males (age 32.4 ± 9.61 years,
Bartesaghi, M +8 more
core +1 more source
Carbohydrate supplementation and psychophysiological responses during moderate exercise in hypoxia
Background Rating of Perceived Exertion (RPE) is a subjective scale to monitor overload and fatigue during exercise. Hypoxia may worsen the perception of fatigue, compromising the self-reported perception of effort and increasing RPE.
E. Tavares-Silva +5 more
doaj +1 more source
Support Your Recovery Needs (SYRN) – a systemic approach to improve sport performance
Study aim: The aim of this study was to present the Support Your Recovery Needs (SYRN) recovery system based on scientifically confirmed methods, addressing the needs of athletes based on their subjective feelings of fatigue after training or competition.
Adamczyk Jakub Grzegorz
doaj +1 more source
In-season training load quantification of one-, two- and three-game week schedules in a top European professional soccer team [PDF]
Top European soccer teams that play in UEFA competitions often participate in one, two- or three-games per week. Therefore, it is necessary to ensure optimal match-day performance and full recovery.
Brito, João +7 more
core +1 more source
Oxidative stress-mediated TXNIP loss causes RPE dysfunction
The disruption of the retinal pigment epithelium (RPE), for example, through oxidative damage, is a common factor underlying age-related macular degeneration (AMD).
Min Ji Cho +11 more
semanticscholar +1 more source

