Results 71 to 80 of about 208,874 (328)

The RPE Cell and the Immune System

Retinal Pigment Epithelium in Health and Disease, 2019
The RPE cell plays a pivotal role in retinal immunity. In fact, the RPE cell orchestrates both innate and adaptive immunity and contains a plethora of factors to regulate the immune response.
B. Detrick, J. Hooks
semanticscholar   +1 more source

Generation of an Induced Pluripotent Stem Cell‐Derived Alveolar Type II In Vitro Model to Study Influenza A Virus Infection and Drug Treatments

Advanced Healthcare Materials, EarlyView.
Patient‐specific induced pluripotent stem cells (iPSCs) can be differentiated into alveolar type II cells (iAT2s), expanded as 3D alveolospheres, and grown at physiologically relevant air–liquid interface (ALI). This study shows for the first time the infectability of iAT2s by the influenza A virus (IAV) and proves their responsiveness to the well ...
Lena Gauthier, Hristina Koceva, Yann Bachelot, Rosanne W. Koutstaal, Puck B. van Kasteren, Marc Thilo Figge, Christian Eggeling, Alexander Sandy Mosig   +7 more
wiley   +1 more source

Slowed response to peripheral visual stimuli during strenuous exercise [PDF]

, 2016
Recently, we proposed that strenuous exercise impairs peripheral visual perception because visual responses to peripheral visual stimuli were slowed during strenuous exercise.
Akira Kiyonaga, Hiroaki Tanaka, Masahiro Kokubu, Mizuki Sudo, Soichi Ando, Takaaki Komiyama, Yasuki Higaki   +6 more
core   +2 more sources

Zinc Protects Oxidative Stress-Induced RPE Death by Reducing Mitochondrial Damage and Preventing Lysosome Rupture

Oxidative Medicine and Cellular Longevity, 2017
Zinc deficiency is known to increase the risk of the development of age-related macular degeneration (AMD), although the underlying mechanism remains poorly defined.
Dinusha Rajapakse, T. Curtis, Mei Chen, Heping Xu   +3 more
semanticscholar   +1 more source

Improving the Robustness of Visual Teach‐and‐Repeat Navigation Using Drift Error Correction and Event‐Based Vision for Low‐Light Environments

Advanced Robotics Research, EarlyView.
Visual teach‐and‐repeat (VTR) navigation allows robots to learn and follow routes without building a full metric map. We show that navigation accuracy for VTR can be improved by integrating a topological map with error‐drift correction based on stereo vision.
Fuhai Ling, Ze Huang, Tony J. Prescott
wiley   +1 more source

Identification of miRNA signatures during the differentiation of hESCs into retinal pigment epithelial cells. [PDF]

PLoS ONE, 2012
Retinal pigment epithelium (RPE) cells can be obtained through in vitro differentiation of both embryonic stem cells (ESCs) and induced pluripotent stem cells (iPSCs).
Ganlu Hu, Kevin Huang, Juehua Yu, Sailesh Gopalakrishna-Pillai, Jun Kong, He Xu, Zhenshan Liu, Kunshan Zhang, Jun Xu, Yuping Luo, Siguang Li, Yi E Sun, Linda E Iverson, Zhigang Xue, Guoping Fan   +14 more
doaj   +1 more source

Impaired Cargo Clearance in the Retinal Pigment Epithelium (RPE) Underlies Irreversible Blinding Diseases

Cells, 2018
Chronic degeneration of the Retinal Pigment Epithelium (RPE) is a precursor to pathological changes in the outer retina. The RPE monolayer, which lies beneath the neuroretina, daily internalises and digests large volumes of spent photoreceptor outer ...
E. Keeling, A. Lotery, David A. Tumbarello, J. Ratnayaka   +3 more
semanticscholar   +1 more source

Logic‐Gated HSV‐TK/GCV Suicide Gene Circuit for Triple‐Negative Breast Cancer

Advanced Science, EarlyView.
The BRAS comprises two modular genetic components driven by distinct tumor‐specific promoters and a failsafe layer with the NOT gate. This multi‐input logic gate circuit enables precise, specific expression of HSV‐TK in breast cancer cells with hardly expression in normal cell and effectively inhibits tumor growth in a triple‐negative breast cancer ...
Shasha Tang, Yuan Fang, Lingli Jin, Dongyang Liu, Yicheng Liu, Ruijia Zheng, Liyun Yong, Xin Wu, Longliang Qiao, Meiyan Wang, Fengfeng Cai   +10 more
wiley   +1 more source

Effects of two types of distractions on ratings of perceived exertion and affective response during acute high-intensity cycling exercise for fair cardiorespiratory fitness level in men

Journal of Physical Fitness and Sports Medicine
This study examined the effects of distractions on ratings of perceived exertion (RPE) and affective responses during acute high intensity cycling exercises.
Shun Wakatabe, Yoichi Hayashi
doaj   +1 more source

Fenofibrate Ameliorates Retinal Pigment Epithelium Injury Induced by Excessive Fat Through Upregulation of PI3K/AKT Signaling

Drug Design, Development and Therapy, 2023
Xue Wang,1– 3 Xiaomei Liu,2 Radouil Tzekov,4 Chaofeng Yu,1 Jiasong Yang,1,5 Yuliang Feng,1 Yajun Wu,1 Yali Xu,1 Shiying Li,6 Wensheng Li1,5,7 1Aier School of Ophthalmology, Central South University, Changsha, People’s Republic of China; 2Suzhou Institute
Wang X, Liu X, Tzekov R, Yu C, Yang J, Feng Y, Wu Y, Xu Y, Li S, Li W   +9 more
doaj