Results 71 to 80 of about 74,456 (268)

The Influence of Playing Position and Contextual Factors on Soccer Players’ Match Differential Ratings of Perceived Exertion: A Preliminary Investigation

Sports, 2018
(1) Background: Differential RPE (dRPE) separates scores for breathlessness (RPE-B), leg muscle exertion (RPE-L) and technical/cognitive exertion (RPE-T).
Steve Barrett, Shaun McLaren, Iain Spears, Patrick Ward, Matthew Weston   +4 more
doaj   +1 more source

Homogenous Cell Transplantation Trials in Parkinson's Disease: A Systematic Review and Meta‐Analysis

Movement Disorders Clinical Practice, EarlyView.
Abstract Background The transplantation of homogenous cells has emerged as an investigational strategy for Parkinson's disease (PD), offering an alternative to symptomatic treatment. Objective We performed a systematic review and meta‐analysis to assess its clinical efficacy and safety.
Nolan Reinisch, Athena Mancini, Adham Elsherbini, Jason Yuen, Andres Lozano   +4 more
wiley   +1 more source

Low‐contrast visual acuity versus low‐luminance visual acuity in choroideremia

Clinical and Experimental Optometry, EarlyView., 2020
Clinical relevance Choroideremia is a progressive X‐linked inherited rod‐cone dystrophy. Patients present with nyctalopia and progressive visual field loss, but visual acuity remains well preserved early on. This study showed that low‐luminance visual acuity may be a useful clinical outcome measure during earlier disease stages.
Laura J Wood, Jasleen K Jolly, Colm D Andrews, Iain R Wilson, Doron Hickey, Jasmina Cehajic‐Kapetanovic, Robert E MacLaren   +6 more
wiley   +1 more source

Key Interventions in Friedreich's Ataxia and Their Impact on Patient Outcomes: A Systematic Review

Movement Disorders, EarlyView.
Abstract Friedreich's ataxia (FA) is a rare neurodegenerative disease with multisystemic symptoms that requires multidisciplinary care. This systematic review summarizes available pharmacological and nonpharmacological interventions, their outcomes, and alignment with patient‐centered care domains, as well as their impact on these domains.
Dorota Sarwinska, Maresa Buchholz, Audrey Iskandar, Marcus Grobe‐Einsler, Thomas Klockgether, Jennifer Faber, Bernhard Michalowsky   +6 more
wiley   +1 more source

Regeneration of the zebrafish retinal pigment epithelium after widespread genetic ablation.

PLoS Genetics, 2019
The retinal pigment epithelium (RPE) is a specialized monolayer of pigmented cells within the eye that is critical for maintaining visual system function.
Nicholas J Hanovice, Lyndsay L Leach, Kayleigh Slater, Ana E Gabriel, Dwight Romanovicz, Enhua Shao, Ross Collery, Edward A Burton, Kira L Lathrop, Brian A Link, Jeffrey M Gross   +10 more
doaj   +1 more source

Identification of miRNA signatures during the differentiation of hESCs into retinal pigment epithelial cells.

PLoS ONE, 2012
Retinal pigment epithelium (RPE) cells can be obtained through in vitro differentiation of both embryonic stem cells (ESCs) and induced pluripotent stem cells (iPSCs).
Ganlu Hu, Kevin Huang, Juehua Yu, Sailesh Gopalakrishna-Pillai, Jun Kong, He Xu, Zhenshan Liu, Kunshan Zhang, Jun Xu, Yuping Luo, Siguang Li, Yi E Sun, Linda E Iverson, Zhigang Xue, Guoping Fan   +14 more
doaj   +1 more source

Navigating the Complexity: A Comprehensive Review of GSK‐3 Inhibition in Regenerative Medicine

Medicinal Research Reviews, EarlyView.
ABSTRACT Glycogen synthase kinase‐3 (GSK‐3) is a central regulator of numerous cellular signaling pathways, with critical roles in metabolism, proliferation, differentiation, and tissue regeneration. This review explores the multifaceted effects of pharmacological GSK‐3 inhibition across multiple body districts, focusing on its highly context‐dependent
Davide Schiroli, Alessia Merra, Chiara Marraccini, Lucia Merolle, Graziella Pellegrini, Eleonora Maurizi   +5 more
wiley   +1 more source

Implications of a twelve-week aerobic exercise on functional work capacity in HIV positive clients on antiretroviral therapy

Turkish Journal of Kinesiology
The implications of aerobic exercise on functional work capacity of Human Immunodeficiency Virus (HIV) positive clients on antiretroviral therapy (ART) in Uganda have been established.
Mwebaze Nicholas, Mshilla Maghanga, Edward Ojuka, Constance A.n. Nsibambi   +3 more
doaj   +1 more source

First genome sequence of a European Alternaria brassicae isolate and genes involved in early development of alternaria leaf spot on Brassica juncea

Pest Management Science, EarlyView.
This article reports the first genome sequence of a UK Alternaria brassicae isolate. Dual RNA‐sequencing profiling of A. brassicae‐infected Brassica juncea leaves identified differentially expressed genes involved in pathogenicity and host response pathways in moderately resistant Sej‐2 (2) and moderately susceptible Pusa Jaikisan cultivars.
Kevin M. King, Graham McLaughlin, Chinthani S. Karandeni Dewage, Zedi Gao, David J. Hughes, Jonathan S. West, Henrik U. Stotz   +6 more
wiley   +1 more source

Temporal dynamics of co‐inoculation of Leptosphaeria maculans and Leptosphaeria biglobosa determine interspecific competition and disease development on oilseed rape

Pest Management Science, EarlyView.
This study provides evidence that the timing of co‐inoculation of Leptosphaeria maculans and Leptosphaeria biglobosa determine the outcome of interspecific competition and disease development on their host oilseed rape. Abstract BACKGROUND Phoma stem canker is one of the most economically damaging diseases of oilseed rape, caused by co‐existing fungal ...
Evren Bingol, Chinthani S. Karandeni Dewage, Aiming Qi, Faye Ritchie, Bruce DL Fitt, Yong‐Ju Huang   +5 more
wiley   +1 more source